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Strictosidine glucosidase from suspension cultured cells of Tabernaemontana divaricata
1996
Luijendijk, T.J.C.; Nowak, A.; Verpoorte, R.
Phytochemistry
41
1451-1456
-
Purification and characterization of strictosidine beta-D-glucosidase from Catharanthus roseus cell suspension cultures
1998
Luijendijk, T.J.C.; Stevens, L.H.; Verpoorte, R.
Plant Physiol. Biochem.
36
419-425
-
New strictosidine beta-glucosidase from Strychnos mellodora
2000
Brandt, V.; Geerlings, A.; Tits, M.; Delaude, C.; van der Heijden, R.; Verpoorte, R.; Angenot, L.
Plant Physiol. Biochem.
38
187-192
Subcellular localization of tryptophan decarboxylase, strictosidine synthase and strictosidine glucosidase in suspension cultured cells of Catharanthus roseus and Tabernaemontana divaricata
1993
Stevens, L.H.; Blom, T.J.M.; Verpoorte, R.
Plant Cell Rep.
12
573-576
Molecular cloning and analysis of strictosidine beta-D-glucosidase, an enzyme in terpenoid indole alkaloid biosynthesis in Catharanthus roseus
2000
Geerlings, A.; Martinez-Lozano Ibanez, M.; Memlink, J.; van der Heijden, R.; Verpoorte, R.
J. Biol. Chem.
275
3051-3056
Glucosidases involved in indole alkaloid biosynthesis of Catharanthus cell culture
1980
Hemscheid, T.; Zenk, M.H.
FEBS Lett.
110
187-191
Heterologous expression of the plant proteins strictosidine synthase and berberine bridge enzyme in insect cell culture
1994
Kutchan, T.M.; Bock, A.; Dittrich, H.
Phytochemistry
35
353-360
Molecular cloning and functional bacterial expression of a plant glucosidase specifically involved in alkaloid biosynthesis
2000
Warzecha, H.; Gerasimenko, I.; Kutchan, T.M.; Stockigt, J.
Phytochemistry
54
657-666
Purification and properties of strictosidine synthase, the key enzyme in indole alkaloid formation
1979
Treimer, J.F.; Zenk, M.H.
Eur. J. Biochem.
101
225-233
Purification and properties of strictosidine synthetase (an enzyme condensing tryptamine and secologanin) from Catharanthus roseus cultured cell
1979
Mizukami, H.; Nordlov, H.; Lee, S.L.; Scott, A.I.
Biochemistry
18
3760-3763
-
Strictosidine synthase from cell cultrues of Apocynaceae plants
1979
Treimer, J.F.; Zenk, M.H.
FEBS Lett.
97
159-162
Immobilization of strictosidine synthase from Catharanthus cell cultures and preparative synthesis of strictosidine
1982
Pfitzner, U.; Zenk, M.H.
Planta Med.
46
10-14
-
Tryptophan decarboxylase, strictosidine synthase and alkaloid production by Cinchona ledgerinana suspension cultures
1987
Skinner, S.E.; Walton, N.J.; Robins, R.J.; Rhodes, M.J.C.
Phytochemistry
26
721-725
-
Isoation and immobilization of strictosidine synthase
1987
Pfitzner, U.; Zenk, M.H.
Methods Enzymol.
136
342-350
-
Homogeneous strictosidine synthase from cell suspension cultures of Rauvolfia serpentina
1988
Hampp, N.; Zenk, M.H.
Phytochemistry
27
3811-3815
Assay of trictosidine synthase from plant cell cultures by high-performance liquid chromatography
1989
Pennings, E.J.M.; Van den Bosch, R.A.; Van der Heijden, R.; Stevens, L.H.; Duine, J.A.; Verpoorte, R.
Anal. Biochem.
176
412-415
Purification of an indole alkaloid biosynthetic enzyme, strictosidine synthase, from a recombinant strain of Escherichia coli
1992
Roessner, C.A.; Devagupta, R.; Hasan, M.; Williams, H.J.; Scott, A.I.
Protein Expr. Purif.
3
295-300
Strictosidine synthase from Rauvolfia serpentina: analysis of a gene involved in indole alkaloid biosynthesis
1992
Bracher, D.; Kutchan, T.M.
Arch. Biochem. Biophys.
294
717-723
-
Purification and characterization of strictosidine synthase from a suspension culture of Cinchona robusta
1993
Stevens, L.H.; Giroud, C.; Pennings, E.J.M.; Verpoorte, R.
Phytochemistry
33
99-106
Strictosidine synthase from Catharanthus roseus: purification and characterization of multiple forms
1995
de Waal, A.; Meijer, A.H.; Verpoorte, R.
Biochem. J.
306
571-580
Suspension cultured transgenic cells of Nicotiana tabacum expressing tryptophan decarboxylase and strictosidine synthase cDNAs from Catharanthus roseus produce strictosidine upon secologanin feeding.
1997
Hallard, D.; Van der Heijden, R.; Verpoorte, R.; Lopes Cardoso, M.I.; Pasquali, G.; Memelink, J.; Hoge, J.H.C.
Plant Cell Rep.
17
50-54
Effects of over-expression of strictosidine synthase and tryptophan decarboxylase on alkaloid production by cell cultures of Catharanthus roseus
1998
Canel, C.; Lopes-Cardoso, M.I.; Whitmer, S.; van der Fits, L.; Pasquali, G.; van der Heijden, R.; Hoge, J.H.; Verpoorte, R.
Planta
205
414-419
The promoter of the strictosidine synthase gene from periwinkle confers elicitor-inducible expression in transgenic tobacco and binds nuclear factors GT-1 and GBF
1999
Pasquali, G.; Erven, A.S.; Ouwerkerk, P.B.; Menke, F.L.; Memelink, J.
Plant Mol. Biol.
39
1299-1310
-
Effect of precursor feeding on alkaloid accumulation by a strictosidine synthase over-expressing transgenic cell line S1 of Catharanthus roseus
2002
Whitmer, S.; van der Heijden, R.; Verpoorte, R.
Plant Cell Tissue Organ Cult.
69
85-93
Metabolite profiling of alkaloids and strictosidine synthase activity in camptothecin producing plants
2003
Yamazaki, Y.; Urano, A.; Sudo, H.; Kitajima, M.; Takayama, H.; Yamazaki, M.; Aimi, N.; Saito, K.
Phytochemistry
62
461-470
Heterologous expression of a Rauvolfia cDNA encoding strictosidine glucosidase, a biosynthetic key to over 2000 monoterpenoid indole alkaloids
2002
Gerasimenko, I.; Sheludko, Y.; Ma, X.; Stockigt, J.
Eur. J. Biochem.
269
2204-2213
localization of tabersonine 16-hydroxylase and 16-OH tabersonine-16-O-methyltransferase to leaf epidermal cells defines them as a major site of precursor biosynthesis in the vindoline pathway in Catharanthus roseus
2005
Murata, J.; De Luca, V.
Plant J.
44
581-594
Substrate specificity and diastereoselectivity of strictosidine glucosidase, a key enzyme in monoterpene indole alkaloid biosynthesis
2007
Yerkes, N.; Wu, J.X.; McCoy, E.; Galan, M.C.; Chen, S.; OConnor, S.E.
Bioorg. Med. Chem. Lett.
18
3095-3098
Redesign of a central enzyme in alkaloid biosynthesis
2006
Chen, S.; Galan, M.C.; Coltharp, C.; OConnor, S.E.
Chem. Biol.
13
1137-1141
Rapid identification of enzyme variants for reengineered alkaloid biosynthesis in periwinkle
2007
Bernhardt, P.; McCoy, E.; OConnor, S.E.
Chem. Biol.
14
888-897
Structure-based engineering of strictosidine synthase: auxiliary for alkaloid libraries
2007
Loris, E.A.; Panjikar, S.; Ruppert, M.; Barleben, L.; Unger, M.; Schuebel, H.; Stoeckigt, J.
Chem. Biol.
14
979-985
Strictosidine synthase: mechanism of a Pictet-Spengler catalyzing enzyme
2008
Maresh, J.J.; Giddings, L.A.; Friedrich, A.; Loris, E.A.; Panjikar, S.; Trout, B.L.; Stoeckigt, J.; Peters, B.; OConnor, S.E.
J. Am. Chem. Soc.
130
710-723
-
The molecular architecture of major enzymes from ajmaline biosynthetic pathway
2007
Stoeckigt, J.; Panjikar, S.; Ruppert, M.; Barleben, L.; Ma, X.; Loris, E.; Hill, M.
Phytochem. Rev.
6
15-34
The new beta-D-glucosidase in terpenoid-isoquinoline alkaloid biosynthesis in Psychotria ipecacuanha
2008
Nomura, T.; Quesada, A.L.; Kutchan, T.M.
J. Biol. Chem.
283
34650-34659
Influence of cellular differentiation and elicitation on intermediate and late steps of terpenoid indole alkaloid biosynthesis in Catharanthus roseus
2010
Shukla, A.K.; Shasany, A.K.; Verma, R.K.; Gupta, M.M.; Mathur, A.K.; Khanuja, S.P.
Protoplasma
242
35-47
Structures of alkaloid biosynthetic glucosidases decode substrate specificity
2012
Xia, L.; Ruppert, M.; Wang, M.; Panjikar, S.; Lin, H.; Rajendran, C.; Barleben, L.; Stoeckigt, J.
ACS Chem. Biol.
7
226-234
Strictosidine activation in Apocynaceae: Towards a nuclear time bomb?
2010
Guirimand, G.; Courdavault, V.; Lanoue, A.; Mahroug, S.; Guihur, A.; Blanc, N.; Giglioli-Guivarch, N.; St-Pierre, B.; Burlat, V.
BMC Plant Biol.
10
182
Strictosidine-related enzymes involved in the alkaloid biosynthesis of Uncaria tomentosa root cultures grown under oxidative stress
2013
Vera-Reyes, I.; Huerta-Heredia, A.A.; Ponce-Noyola, T.; Flores-Sanchez, I.J.; Esparza-Garcia, F.; Cerda-Garcia-Rojas, C.M.; Trejo-Tapia, G.; Ramos-Valdivia, A.C.
Biotechnol. Prog.
29
621-630
Expression patterns of genes involved in the defense and stress response of Spiroplasma citri infected Madagascar periwinkle Catharanthus roseus
2012
Nejat, N.; Vadamalai, G.; Dickinson, M.
Int. J. Mol. Sci.
13
2301-2313
Ligand structures of synthetic deoxa-pyranosylamines with raucaffricine and strictosidine glucosidases provide structural insights into their binding and inhibitory behaviours
2015
Xia, L.; Lin, H.; Staniek, A.; Panjikar, S.; Ruppert, M.; Hilgers, P.; Williardt, J.; Rajendran, C.; Wang, M.; Warzecha, H.; Jäger, V.; Stöckigt, J.
J. Enzyme Inhib. Med. Chem.
30
472-478
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