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Ligand 5-[(prop-2-en-1-yl)oxy]-2-(pyrrolidin-1-yl)quinoline Please wait a moment until all data is loaded. This message will disappear when all data is loaded.
Basic Ligand Information
C1 6 H1 8 N2 O
5-[(prop-2-en-1-yl)oxy]-2-(pyrrolidin-1-yl)quinoline
LQEMJTVBSHSJNA-UHFFFAOYSA-N
Roles as Enzyme Ligand
Inhibitor in Enzyme-catalyzed Reactions (1 result)
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SETDB1 SET domain inhibitor, inhibits SETDB1 activity and H3K9me3 expression, and improves motor function and neuropathological symptoms with minimal toxicity in mouse HD models
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Enzyme Kinetic Parameters
References & Links Literature References (1)
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SETDB1, an H3K9-specific methyltransferase An attractive epigenetic target to combat cancer
2024
Prashanth, S.; Radha Maniswami, R.; Rajajeyabalachandran, G.; Jegatheesan, S.K.
Drug Discov. Today
29
103982
Links to other databases for 5-[(prop-2-en-1-yl)oxy]-2-(pyrrolidin-1-yl)quinoline