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Ligand a [methyl-Co(III) methanol-specific corrinoid protein]

Basic Ligand Information

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Roles as Enzyme Ligand

In Vivo Substrate in Enzyme-catalyzed Reactions (2 results)

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Show Natural Substrate (2 entries)

EC NUMBER

PROVEN IN VIVO REACTION

REACTION DIAGRAM

LITERATURE

ENZYME 3D STRUCTURE

2.1.1.246

a [methyl-Co(III) methanol-specific corrinoid protein] + coenzyme M = methyl-CoM + a [Co(I) methanol-specific corrinoid protein]

717559, 717562, 717561, 717563, 717753

-

2.1.1.246

a [methyl-Co(III) methanol-specific corrinoid protein] + CoM = methyl-CoM + a [Co(I) methanol-specific corrinoid protein]

756274

-

2.1.1.246

2 entries

In Vivo Product in Enzyme-catalyzed Reactions (1 result)

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Show Natural Product (1 entry)

EC NUMBER

PROVEN IN VIVO REACTION

REACTION DIAGRAM

LITERATURE

ENZYME 3D STRUCTURE

2.1.1.90

methanol + a [Co(I) methanol-specific corrinoid protein] = a [methyl-Co(III) methanol-specific corrinoid protein] + H2O

0

-

Substrate in Enzyme-catalyzed Reactions (3 results)

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Show Substrate (3 entries)

EC NUMBER

REACTION

REACTION DIAGRAM

LITERATURE

ENZYME 3D STRUCTURE

2.1.1.246

a [methyl-Co(III) methanol-specific corrinoid protein] + 3-mercaptopropanoic acid = methyl-3-mercaptopropanoic acid + a [Co(I) methanol-specific corrinoid protein]

717753

-

2.1.1.246

a [methyl-Co(III) methanol-specific corrinoid protein] + coenzyme M = methyl-CoM + a [Co(I) methanol-specific corrinoid protein]

717559, 717562, 717561, 717563, 717753

-

2.1.1.246

a [methyl-Co(III) methanol-specific corrinoid protein] + CoM = methyl-CoM + a [Co(I) methanol-specific corrinoid protein]

756274

-

2.1.1.246

3 entries

Product in Enzyme-catalyzed Reactions (1 result)

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Show Product (1 entry)

EC NUMBER

REACTION

REACTION DIAGRAM

LITERATURE

ENZYME 3D STRUCTURE

2.1.1.90

methanol + a [Co(I) methanol-specific corrinoid protein] = a [methyl-Co(III) methanol-specific corrinoid protein] + H2O

0

-

Enzyme Kinetic Parameters

References & Links

Literature References (6)

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Show Reference (6 entries)

BRENDA REFERENCE ID

PUBMED ID

TITLE

YEAR

AUTHORS

JOURNAL

VOLUME

PAGES

717559

9654068

Methanol:coenzyme M methyltransferase from Methanosarcina barkeri - identification of the active-site histidine in the corrinoid-harboring subunit MtaC by site-directed mutagenesis

1998

Sauer, K.; Thauer, R.K.

Eur. J. Biochem.

253

698-705

717561

10215883

Methanol:coenzyme M methyltransferase from Methanosarcina barkeri - substitution of the corrinoid harbouring subunit MtaC by free cob(I)alamin

1999

Sauer, K.; Thauer, R.K.

Eur. J. Biochem.

261

674-681

717562

10785368

Methyl-coenzyme M formation in methanogenic archaea. Involvement of zinc in coenzyme M activation

2000

Sauer, K.; Thauer, R.K.

Eur. J. Biochem.

267

2498-2504

717563

11985589

The role of zinc in the methylation of the coenzyme M thiol group in methanol:coenzyme M methyltransferase from Methanosarcina barkeri: new insights from X-ray absorption spectroscopy

2002

Krüer, M.; Haumann, M.; Meyer-Klaucke, W.; Thauer, R.; Dau, H.

Eur. J. Biochem.

269

2117-2123

717753

8702528

Methylcobamide:coenzyme M methyltransferase isozymes from Methanosarcina barkeri. Physicochemical characterization, cloning, sequence analysis, and heterologous gene expression

1996

LeClerc, G.M.; Grahame, D.A.

J. Biol. Chem.

271

18725-18731

756274

28556629

In vitro methanol production from methyl coenzyme M using the Methanosarcina barkeri MtaABC protein complex

2017

Dong, M.; Gonzalez, T.; Klems, M.; Steinberg, L.; Chen, W.; Papoutsakis, E.; Bahnson, B.

Biotechnol. Prog.

33

1243-1249

Links to other databases for a [methyl-Co(III) methanol-specific corrinoid protein]

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