Ligand (6E)-8-hydroxylinalool
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Basic Ligand Information
Molecular Structure

C10H18O2
(6E)-8-hydroxylinalool
NSMIMJYEKVSYMT-RMKNXTFCSA-N
(E)-3,7--Dimethylocta-1,6-dien-3,8-diol, (E)-3,7-Dimethylocta-1,6-dien-3,8-diol, (E)-3,7-dimethylocta-1,6-diene-3,8-diol, 8-hydroxy-linalool
Roles as Enzyme Ligand
In Vivo Product in Enzyme-catalyzed Reactions (1 result)
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3,7-dimethylocta-1,6-dien-3-ol + [reduced NADPH-hemoprotein reductase] + O2 = (E)-3,7-dimethylocta-1,6-dien-3,8-diol + [oxidized NADPH-hemoprotein reductase] + H2O
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Substrate in Enzyme-catalyzed Reactions (2 results)
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(6E)-8-hydroxylinalool + [reduced NADPH-hemoprotein reductase] + O2 = (6E)-8-oxolinalool + [oxidized NADPH-hemoprotein reductase] + H2O
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(E)-3,7-dimethylocta-1,6-dien-3,8-diol + [reduced NADPH-hemoprotein reductase] + O2 = 8-oxolinalool + [oxidized NADPH-hemoprotein reductase] + H2O
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Product in Enzyme-catalyzed Reactions (4 results)
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linalool + NADH + O2 = (6E)-8-hydroxylinalool + NAD+ + H2O
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linalool + [reduced NADPH-hemoprotein reductase] + O2 = (6E)-8-hydroxylinalool + [oxidized NADPH-hemoprotein reductase] + H2O
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3,7-dimethylocta-1,6-dien-3-ol + [reduced NADPH-hemoprotein reductase] + O2 = (E)-3,7-dimethylocta-1,6-dien-3,8-diol + [oxidized NADPH-hemoprotein reductase] + H2O
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linalool + O2 + reduced putidaredoxin = 8-hydroxy-linalool + oxidized putidaredoxin + H2O
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Enzyme Kinetic Parameters
References & Links
Literature References (2)
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Chemical probes into the active centre of a heme thiolate monoxygenase
1984
Bhattacharyya, P.K.; Samanta, T.B.; Ullah, A.H.J.; Gunsalus, I.C.
Proc. Indian Acad. Sci. Chem. Sci.
93
1289-1304
Protein components of a cytochrome P-450 linalool 8-methyl hydroxylase
1990
Ullah, A.H.J.; Murray, R.I.; Bhattacharyya, P.K.; Wagner, G.C.; Gunsalus, I.C.
J. Biol. Chem.
265
1345-1351
Links to other databases for (6E)-8-hydroxylinalool