Ligand L-4-hydroxythreonine

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Basic Ligand Information

Molecular Structure
Picture of L-4-hydroxythreonine (click for magnification)
Molecular Formula
BRENDA Name
InChIKey
C4H9NO4
L-4-hydroxythreonine
JBNUARFQOCGDRK-GBXIJSLDSA-N
Synonyms:
4-hydroxy-L-threonine, L-threo-3-hydroxyhomoserine
Pathway Source
Pathways

Roles as Enzyme Ligand

In Vivo Product in Enzyme-catalyzed Reactions (1 result)

EC NUMBER
PROVEN IN VIVO REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
glycine + glycolaldehyde = L-4-hydroxythreonine
show the reaction diagram
-
-

Substrate in Enzyme-catalyzed Reactions (3 results)

EC NUMBER
REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
ATP + 4-hydroxy-L-threonine = ADP + 4-phospho-L-threonine
show the reaction diagram
-
ATP + 4-hydroxy-L-threonine = ADP + 4-phospho-L-threonine
show the reaction diagram
-
L-4-hydroxythreonine = glycine + glycolaldehyde
show the reaction diagram
-

Product in Enzyme-catalyzed Reactions (1 result)

EC NUMBER
REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
glycine + glycolaldehyde = L-4-hydroxythreonine
show the reaction diagram
-
-

Inhibitor in Enzyme-catalyzed Reactions (2 results)

EC NUMBER
COMMENTARY
LITERATURE
ENZYME 3D STRUCTURE

Enzyme Kinetic Parameters

kcat Value (Turnover Number) (4 results)

EC NUMBER
TURNOVER NUMBER [1/S]
TURNOVER NUMBER MAXIMUM [1/S]
COMMENTARY
LITERATURE
41
-
pH 8.0, 25°C
1.44
-
pH 8.0, 25°C

KM Value (4 results)

EC NUMBER
KM VALUE [MM]
KM VALUE MAXIMUM [MM]
COMMENTARY
LITERATURE
44
-
pH 8.0, 25°C
0.027
-
pH 8.0, 25°C

Ki Value (1 result)

EC NUMBER
KI VALUE [MM]
KI VALUE MAXIMUM [MM]
COMMENTARY
LITERATURE
0.006
-
-

References & Links

Links to other databases for L-4-hydroxythreonine

ChEBI
PubChem
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PubChem