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BRENDA support

Ligand isoascorbic acid

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Basic Ligand Information

Molecular Structure
Picture of isoascorbic acid (click for magnification)
Molecular Formula
BRENDA Name
InChIKey
C6H8O6
isoascorbic acid
CIWBSHSKHKDKBQ-MVHIGOERSA-N
Synonyms:
2-dehydroisoascorbate, isoascorbate

Roles as Enzyme Ligand

Substrate in Enzyme-catalyzed Reactions (1 result)

EC NUMBER
REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
alpha-cyclodextrin + isoascorbic acid = L-isoascorbic acid-2-O-alpha-D-glucoside + L-isoascorbic acid-2-O-alpha-D-oligoglucoside
show the reaction diagram
-

Product in Enzyme-catalyzed Reactions (4 results)

EC NUMBER
REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
NADH + monodehydroisoascorbate = NAD+ + isoascorbate
show the reaction diagram
-
GSH + isodehydroascorbate = GSSG + isoascorbate
show the reaction diagram
-

Enzyme Cofactor/Cosubstrate (1 result)

EC NUMBER
COMMENTARY
LITERATURE
ENZYME 3D STRUCTURE
may substitute for ascorbate, 75% of the efficiency of ascorbate
-

Activator in Enzyme-catalyzed Reactions (4 results)

EC NUMBER
COMMENTARY
LITERATURE
ENZYME 3D STRUCTURE
increase of activity
-
partial activation
-
prevents degradation of tetrapyrroles by reactive oxygen species
-

Inhibitor in Enzyme-catalyzed Reactions (8 results)

EC NUMBER
COMMENTARY
LITERATURE
ENZYME 3D STRUCTURE
competitive inhibitor
-

3D Structure of Enzyme-Ligand-Complex (PDB) (1 result)

EC NUMBER
ENZYME 3D STRUCTURE

Enzyme Kinetic Parameters

IC50 Value (13 results)

EC NUMBER
IC50 VALUE
IC50 VALUE MAXIMUM
COMMENTARY
LITERATURE

References & Links

Links to other databases for isoascorbic acid

ChEBI
PubChem
ChEBI
PubChem