Ligand benzoyl-L-Arg

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Basic Ligand Information

Molecular Structure
Picture of benzoyl-L-Arg (click for magnification)
Molecular Formula
BRENDA Name
InChIKey
C13H18N4O3
benzoyl-L-Arg
RSYYQCDERUOEFI-JTQLQIEISA-N
Synonyms:
alpha-N-benzoyl-Arg, alpha-N-benzoyl-L-Arg, alpha-N-benzoyl-L-arginine, benzoyl-Arg, benzoyl-arginine, benzoyl-argininic acid, benzoyl-L-arginine, benzoylarginine, Bz-L-Arg, L-Bz-Arg, N-alpha-benzoyl-Arg, N-alpha-benzoyl-L-Arg, N-alpha-benzoyl-L-arginine, N-benzoyl-L-Arg, N-benzoyl-L-arginine, N2-benzoyl-L-arginine, Nalpha-benzoyl-Arg, Nalpha-benzoyl-L-Arg, Nalpha-benzoyl-L-arginine

Roles as Enzyme Ligand

Substrate in Enzyme-catalyzed Reactions (14 results)

EC NUMBER
LITERATURE
REACTION DIAGRAM
REACTION
ENZYME 3D STRUCTURE
show the reaction diagram
benzoyl-argininic acid + H2O = ?
-
show the reaction diagram
Nalpha-benzoyl-L-arginine + H2O = ?
-
show the reaction diagram
benzoyl-L-Arg + ethanol = benzoyl-L-Arg ethyl ester + H2O
-
show the reaction diagram
Nalpha-benzoyl-L-Arg + H2O = benzoic acid + L-Arg
-
show the reaction diagram
N-benzoyl-L-arginine + H2O = benzoate + L-arginine
-

Product in Enzyme-catalyzed Reactions (115 results)

EC NUMBER
LITERATURE
REACTION DIAGRAM
REACTION
ENZYME 3D STRUCTURE
-
show the reaction diagram
benzoyl-Arg-p-nitroanilide + H2O = benzoyl-Arg + p-nitroaniline
-
-
show the reaction diagram
benzoyl-Arg-4-nitroanilide + H2O = benzoyl-Arg + 4-nitrolaniline
-
-
show the reaction diagram
N-benzoyl-L-arginine ethyl ester + H2O = N-benzoyl-L-arginine + ethanol
-
-
show the reaction diagram
benzoyl-L-arginine-4-methylcoumaryl-7-amide + H2O = benzoyl-L-arginine + 7-amino-4-methylcoumarin
-
-
show the reaction diagram
N-benzoyl-L-arginine-p-nitroanilide + H2O = N-benzoyl-L-arginine + p-nitroaniline
-
-
show the reaction diagram
Nalpha-Benzoyl-L-Arg ethyl ester + H2O = Nalpha-Benzoyl-L-Arg + ethanol
-
-
show the reaction diagram
benzoyl arginine ethyl ester + H2O = benzoyl-Arg + ethanol
-
show the reaction diagram
benzoyl-Arg-4-methylcoumaryl-7-amide + H2O = benzoyl-Arg + 7-amino-4-methylcoumarin
-
-
show the reaction diagram
Benzoyl-L-Arg methyl ester + H2O = Benzoyl-L-Arg + methanol
-
-
show the reaction diagram
benzoyl-Arg ethyl ester + H2O = benzoyl-Arg + ethanol
-
-
show the reaction diagram
benzoyl-Arg 4-nitroanilide + H2O = benzoyl-Arg + 4-nitroaniline
-
-
show the reaction diagram
benzoyl-Arg 4-nitroanilide + H2O = benzoyl-Arg + 4-nitroaniline
-
-
show the reaction diagram
Benzoyl-L-Arg ethyl ester + H2O = Benzoyl-L-Arg + ethanol
-
-
show the reaction diagram
Benzoyl-L-Arg ethyl ester + H2O = Benzoyl-L-Arg + ethanol
-
-
show the reaction diagram
Nalpha-benzoyl-L-Arg 4-nitroanilide + H2O = Nalpha-benzoyl-L-Arg + 4-nitroaniline
-
-
show the reaction diagram
benzoyl-Arg ethyl ester + H2O = benzoyl-Arg + ethanol
-
-
show the reaction diagram
N-alpha-benzoyl-L-arginine-p-nitroanilide + H2O = N-alpha-benzoyl-L-arginine + p-nitroaniline
-
-
show the reaction diagram
Benzoyl-L-Arg ethyl ester + H2O = Benzoyl-L-Arg + ethanol
-
-
show the reaction diagram
benzoyl-Arg-amido-4-methyl-coumarin + H2O = benzoyl-Arg + 7-amino-4-methylcoumarin
-
-
show the reaction diagram
benzoyl-L-arginine p-nitroanilide + H2O = benzoyl-L-arginine + 4-nitroaniline
-
show the reaction diagram
benzoyl-Arg-4-methylcoumaryl-7-amide + H2O = benzoyl-Arg + 7-amino-4-methylcoumarin
-
-
show the reaction diagram
Benzoyl-Arg 4-methylcoumarin 7-amide + H2O = Benzoyl-Arg + 7-amino-4-methylcoumarin
-
-
show the reaction diagram
Nalpha-benzoyl-L-arginine-7-amido-4-methylcoumarin + H2O = Nalpha-benzoyl-L-arginine + 7-amino-4-methylcoumarin
-
show the reaction diagram
benzoyl-Arg-Ala-Ala-Phe-p-aminobenzoate = benzoyl-Arg + Ala-Ala-Phe-p-aminobenzoate
-
-
show the reaction diagram
N-alpha-benzoyl-arginine p-nitroanilide + H2O = N-alpha-benzoyl-Arg + 4-nitroaniline
-

Inhibitor in Enzyme-catalyzed Reactions (5 results)

COMMENTARY
EC NUMBER
LITERATURE
ENZYME 3D STRUCTURE
with benzoyl-Gly-Arg as substrate
-
product inhibition
-
competitive
-

Enzyme Kinetic Parameters

kcat Value (Turnover Number) (11 results)

COMMENTARY
EC NUMBER
LITERATURE
TURNOVER NUMBER [1/S]
TURNOVER NUMBER MAXIMUM [1/S]
at pH 6.5 and 35°C
3.63
-
37°C
3.35
-
at pH 7.6 and 37°C
0.63
-
native enzyme
1.11
-
pH 7.6, 55°C, peptidylarginine deiminase 1
pH 7.6, 55°C, peptidylarginine deiminase 2
3.15
-
pH 7.6, 55°C, peptidylarginine deiminase 3
0.79
-
recombinant enzyme
1.41
-
in 50 mM CHES/HCl, pH 9.5 containing 10 mM dithiothreitol, at 37°C
0.12
-
in 50 mM K+-HEPES (pH 7.5), at 25°C
2.5
-

KM Value (11 results)

COMMENTARY
EC NUMBER
KM VALUE [MM]
KM VALUE MAXIMUM [MM]
LITERATURE
at pH 6.5 and 35°C
0.014
-
-
0.0029
-
37°C
0.41
-
at pH 7.5 and 37°C
0.41
-
at pH 7.6 and 37°C
1.6
-
native enzyme
2.28
-
pH 7.6, 55°C, peptidylarginine deiminase 1
0.38
-
pH 7.6, 55°C, peptidylarginine deiminase 2
1.49
-
pH 7.6, 55°C, peptidylarginine deiminase 3
33.6
-
recombinant enzyme
2.58
-
in 50 mM CHES/HCl, pH 9.5 containing 10 mM dithiothreitol, at 37°C
0.01
0.02

References & Links

Links to other databases for benzoyl-L-Arg

ChEBI
PubChem
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PubChem