Ligand arachidoyl-CoA

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Basic Ligand Information

Molecular Structure
Picture of arachidoyl-CoA (click for magnification)
Molecular Formula
BRENDA Name
InChIKey
C41H74N7O17P3S
arachidoyl-CoA
JYLSVNBJLYCSSW-IBYUJNRCSA-N
Synonyms:
arachidoyl-coenzyme A, eicosanoyl-CoA, icosanoyl-CoA, n-icosanoyl-CoA

Roles as Enzyme Ligand

In Vivo Substrate in Enzyme-catalyzed Reactions (8 results)

EC NUMBER
PROVEN IN VIVO REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
icosanoyl-CoA + 2 ferrocytochrome b5 + O2 + 2 H+ = (Z)-icos-5-enoyl-CoA + 2 ferricytochrome b5 + 2 H2O
show the reaction diagram
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eicosanoyl-CoA + 4 methylmalonyl-CoA + 8 NADPH + 8 H+ = tetramethyl-branched mycocerosoyl-CoA + 4 CoA + 4 CO2 + 8 NADP+ + 4 H2O
show the reaction diagram
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sphingosine + eicosanoyl-CoA = N-eicosanoylsphingosine + CoA
show the reaction diagram
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In Vivo Product in Enzyme-catalyzed Reactions (1 result)

EC NUMBER
PROVEN IN VIVO REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
trans-2-eicosenoyl-CoA + NADPH = eicosanoyl-CoA + NADP+
show the reaction diagram
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Substrate in Enzyme-catalyzed Reactions (67 results)

EC NUMBER
REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
icosanoyl-CoA + 2 ferrocytochrome b5 + O2 + 2 H+ = (Z)-icos-5-enoyl-CoA + 2 ferricytochrome b5 + 2 H2O
show the reaction diagram
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arachidoyl-CoA + 2 NADPH + 2 H+ = arachidol + 2 NADP+ + coenzyme A
show the reaction diagram
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eicosanoyl-CoA + NADPH = eicosanal + CoA + NADP+
show the reaction diagram
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arachidoyl-CoA + O2 = 2-trans-eicosenoyl-CoA + H2O2
show the reaction diagram
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arachidoyl-CoA + oxidized electron transfer flavoprotein = ? + reduced electron transfer flavoprotein
show the reaction diagram
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arachidoyl-CoA + sn-glycerol 3-phosphate = CoA + 1-arachidoyl-sn-glycerol 3-phosphate
show the reaction diagram
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arachidoyl-CoA + malonyl-[acyl-carrier protein] = 3-oxo-docosanoyl-[acyl-carrier protein] + CoA + CO2
show the reaction diagram
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arachidoyl-CoA + malonyl-CoA = ?
show the reaction diagram
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arachidoyl-CoA + L-carnitine = CoA + L-arachidoylcarnitine
show the reaction diagram
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arachidoyl-CoA + sn-2-monooleoylglycerol = CoA + 1-arachidoyl-2-oleoylglycerol
show the reaction diagram
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arachidoyl-CoA + dihydrosphingosine = N-(arachidoyl)-dihydrosphingosine + CoA
show the reaction diagram
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dihydroxyacetone phosphate + arachidoyl-CoA = 1-arachidoyl-glycerone phosphate + CoA
show the reaction diagram
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arachidoyl-CoA + L-serine = CoA + 2-amino-1-hydroxydocosan-3-one + CO2
show the reaction diagram
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Product in Enzyme-catalyzed Reactions (2 results)

EC NUMBER
REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
trans-2-eicosenoyl-CoA + NADPH = eicosanoyl-CoA + NADP+
show the reaction diagram
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ATP + eicosanoate + CoA = AMP + diphosphate + eicosanoyl-CoA
show the reaction diagram
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Inhibitor in Enzyme-catalyzed Reactions (2 results)

EC NUMBER
COMMENTARY
LITERATURE
ENZYME 3D STRUCTURE
86% residual activity at 0.1 mM
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Enzyme Kinetic Parameters

kcat Value (Turnover Number) (1 result)

EC NUMBER
TURNOVER NUMBER [1/S]
TURNOVER NUMBER MAXIMUM [1/S]
COMMENTARY
LITERATURE
0.27
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pH 7.5, 25°C, determined using the 5,5'-dithiobis(2-nitrobenzoic acid) spectrophotometric assay

KM Value (8 results)

EC NUMBER
KM VALUE [MM]
KM VALUE MAXIMUM [MM]
COMMENTARY
LITERATURE
0.0335
-
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References & Links

Links to other databases for arachidoyl-CoA

ChEBI
PubChem
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PubChem