Ligand 7,8-dihydroneopterin 3'-triphosphate

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Basic Ligand Information

Molecular Structure
Picture of 7,8-dihydroneopterin 3'-triphosphate (click for magnification)
Molecular Formula
BRENDA Name
InChIKey
C9H16N5O13P3
7,8-dihydroneopterin 3'-triphosphate
DGGUVLXVLHAAGT-XINAWCOVSA-N
Synonyms:
1'-3H-dihydroneopterin triphosphate, 2-amino-4-hydroxy-6-(erythro-1,2,3-trihydroxypropyl)-dihydropteridine triphosphate, 2-amino-4-hydroxy-6-(erythro-1,2,3-trihydroxypropyl)dihydropteridine triphosphate, 2-amino-4-hydroxy-6-(erythro-1,2,3-trihydroxypropyl)dihydropteridinetriphosphate, 6-(L-erythro-1,2-dihydroxypropyl 3-triphosphate)-7,8-dihydropterin, 6-[(1S,2R)-1,2-dihydroxy-3-triphosphooxypropyl]-7,8-dihydropterin, 7,8-dihydroneopterin triphosphate, dihydroneopterin triphosphate


Show all pahtways known for Show all BRENDA pathways known for 7,8-dihydroneopterin 3'-triphosphate

Roles as Enzyme Ligand

In Vivo Substrate in Enzyme-catalyzed Reactions (8 results)

EC NUMBER
PROVEN IN VIVO REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
7,8-dihydroneopterin 3'-triphosphate + H2O = 7,8-dihydroneopterin 3'-phosphate + diphosphate
show the reaction diagram
-
7,8-dihydroneopterin 3'-triphosphate + H2O = 6-carboxy-5,6,7,8-tetrahydropterin + acetaldehyde + triphosphate
show the reaction diagram
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7,8-dihydroneopterin 3'-triphosphate = 6-(hydroxymethyl)-7,8-dihydropterin + glycolaldehyde triphosphate
show the reaction diagram
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7,8-dihydroneopterin 3'-triphosphate = 7,8-dihydromonapterin 3'-triphosphate
show the reaction diagram
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In Vivo Product in Enzyme-catalyzed Reactions (4 results)

EC NUMBER
PROVEN IN VIVO REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE

Substrate in Enzyme-catalyzed Reactions (13 results)

EC NUMBER
REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
dihydroneopterin triphosphate + glutathione = ?
show the reaction diagram
-
7,8-dihydroneopterin 3'-triphosphate + H2O = 7,8-dihydroneopterin 3'-phosphate + diphosphate
show the reaction diagram
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7,8-dihydroneopterin 3'-triphosphate = 6-(hydroxymethyl)-7,8-dihydropterin + glycolaldehyde triphosphate
show the reaction diagram
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7,8-dihydroneopterin 3'-triphosphate = 7,8-dihydromonapterin 3'-triphosphate
show the reaction diagram
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7,8-dihydroneopterin triphosphate = 7,8-dihydromonapterin triphosphate
show the reaction diagram
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Product in Enzyme-catalyzed Reactions (5 results)

EC NUMBER
REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE

Enzyme Kinetic Parameters

kcat Value (Turnover Number) (9 results)

EC NUMBER
TURNOVER NUMBER [1/S]
TURNOVER NUMBER MAXIMUM [1/S]
COMMENTARY
LITERATURE

KM Value (39 results)

EC NUMBER
KM VALUE [MM]
KM VALUE MAXIMUM [MM]
COMMENTARY
LITERATURE
0.0085
-
-
0.013
-
pH 6.2, 37°C, recombinant enzyme
0.013
-
pH 8.0, 55°C

References & Links

Links to other databases for 7,8-dihydroneopterin 3'-triphosphate

ChEBI
PubChem
ChEBI
PubChem