Ligand N-stearoylethanolamine
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Basic Ligand Information
Molecular Structure

C20H41NO2
N-stearoylethanolamine
OTGQIQQTPXJQRG-UHFFFAOYSA-N
N-(2-hydroxyethyl)octadecanamide, N-Octadecanoylethanolamine, N-stearoylethanolamide
Roles as Enzyme Ligand
In Vivo Substrate in Enzyme-catalyzed Reactions (1 result)
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N-stearoylethanolamide + H2O = stearate + ethanolamine
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Substrate in Enzyme-catalyzed Reactions (3 results)
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N-octadecanoylethanolamine + H2O = octadecanoic acid + ethanolamine
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N-stearoylethanolamide + H2O = stearate + ethanolamine
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N-(2-hydroxyethyl)octadecanamide + H2O = ?
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Product in Enzyme-catalyzed Reactions (3 results)
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N-stearoyl-1,2-dioleoyl-phosphatidylethanolamine + H2O = N-stearoylethanolamine + 1,2-dioleoyl-sn-glycerol 3-phosphate
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N-stearoyl-1,2-dioleoylphosphatidylethanolamine + H2O = N-stearoylethanolamine + 1,2-dioleoyl-sn-glycerol 3-phosphate
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N-stearoylphosphatidylethanolamine + H2O = N-stearoylethanolamine + phosphatidate
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Inhibitor in Enzyme-catalyzed Reactions (1 result)
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0.005 mM, 14% loss of activity
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Enzyme Kinetic Parameters
References & Links
Literature References (4)
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Properties of rat liver N-acylethanolamine amidohydrolase
1985
Schmid, P.C.; Zuzarte-Augustin, M.L.; Schmid, H.H.O.
J. Biol. Chem.
260
14145-14149
Substrate specificity and stereoselectivity of rat brain microsomal anandamide amidohydrolase
1999
Lang, W.; Qin, C.; Lin, S.; Khanolkar, A.D.; Goutopoulos, A.; Fan, P.; Abouzid, K.; Meng, Z.; Biegel, D.; Makriyannis, A.
J. Med. Chem.
42
898-902
Radiochromatographic assay of N-acyl-phosphatidylethanolamine-specific phospholipase D activity
2005
Fezza, F.; Gasperi, V.; Mazzei, C.; Maccarrone, M.
Anal. Biochem.
339
113-120
Development of new inhibitors for N-acylethanolamine-hydrolyzing acid amidase as promising tool against bladder cancer
2017
Vago, R.; Bettiga, A.; Salonia, A.; Ciuffreda, P.; Ottria, R.
Bioorg. Med. Chem.
25
1242-1249
Links to other databases for N-stearoylethanolamine