Ligand benzyloxycarbonyl-Phe

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Basic Ligand Information

Molecular Structure
Picture of benzyloxycarbonyl-Phe (click for magnification)
Molecular Formula
BRENDA Name
InChIKey
C17H17NO4
benzyloxycarbonyl-Phe
RRONHWAVOYADJL-HNNXBMFYSA-N
Synonyms:
benzyloxycarbonyl-L-Phe, benzyloxycarbonyl-L-phenylalanine, carbobenzoxy-L-Phe, carbobenzoxy-Phe, carboxybenzoyl-Phe, N-(benzyloxycarbonyl)-L-Phe, N-benzyloxycarbonyl-L-Phe, N-carbobenzoxy-L-Phe, N-carbobenzoxyphenylalanine, N-carbobenzyloxy-Phe, N-carbobenzyloxyphenylalanine, N-CBZ-L-phenylalanine, Nalpha-benzyloxycarbonyl-L-Phe, Nalpha-benzyloxycarbonyl-Phe, Nalpha-carbobenzoxy-Phe, Z-L-phenylalanine, Z-Phe, Z-Phe-OH, Z-phenylalanine

Roles as Enzyme Ligand

Substrate in Enzyme-catalyzed Reactions (5 results)

EC NUMBER
REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
N-(Benzyloxycarbonyl)-L-Phe + L-Phe methyl ester = N-(Benzyloxycarbonyl)-L-Phe-L-Phe methyl ester + H2O
show the reaction diagram
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N-CBZ-L-phenylalanine + H2O = ? + L-phenylalanine
show the reaction diagram
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Nalpha-benzyloxycarbonyl-L-Phe + H2O = benzyl alcohol + CO2 + L-Phe
show the reaction diagram
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Product in Enzyme-catalyzed Reactions (39 results)

EC NUMBER
REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
N-carbobenzyloxy-Phe-tRNA + H2O = N-carbobenzyloxy-Phe + tRNA
show the reaction diagram
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benzyloxycarbonyl-Phe-Leu + H2O = benzyloxycarbonyl-Phe + L-leucine
show the reaction diagram
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benzyloxycarbonyl-Phe-Leu + H2O = benzyloxycarbonyl-Phe + Leu
show the reaction diagram
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Carbobenzoxy-Phe-Tyr + H2O = Carbobenzoxy-Phe + Tyr
show the reaction diagram
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benzyloxycarbonyl-Phe-Ala + H2O = benzyloxycarbonyl-Phe + Ala
show the reaction diagram
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benzyloxycarbonyl-Phe-Leu + H2O = benzyloxycarbonyl-Phe + Leu
show the reaction diagram
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benzyloxycarbonyl-Phe-4-nitrophenyl ester + H2O = benzyloxycarbonyl-Phe + 4-nitrophenol
show the reaction diagram
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benzyloxycarbonyl-Phe 4-nitrophenyl ester + H2O = benzyloxycarbonyl-Phe + 4-nitrophenol
show the reaction diagram
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Nalpha-carbobenzoxy-Phe p-nitrophenyl ester + H2O = Nalpha-carbobenzoxy-Phe + 4-nitrophenol
show the reaction diagram
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benzyloxycarbonyl-Phe 4-nitrophenyl ester + H2O = benzyloxycarbonyl-Phe + 4-nitrophenol
show the reaction diagram
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Benzyloxycarbonyl-Phe-Tyr + H2O = Benzyloxycarbonyl-Phe + Tyr
show the reaction diagram
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Z-Phe-Xaa-Ala-Ala + H2O = Z-Phe + Xaa-Ala-Ala
show the reaction diagram
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Benzyloxycarbonyl-Phe-Xaa-Ala + H2O = Benzyloxycarbonyl-Phe + Xaa-Ala
show the reaction diagram
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benzyloxycarbonyl-Phe-Arg-4-methylcoumarin 7-amide + H2O = benzyloxycarbonyl-Phe + Arg-4-methylcoumarin 7-amide
show the reaction diagram
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Inhibitor in Enzyme-catalyzed Reactions (7 results)

EC NUMBER
COMMENTARY
LITERATURE
ENZYME 3D STRUCTURE
inhibition of prekallikrein activation
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benzyloxycarbonyl-Gly-Leu-Ala-Ala as substrate
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Enzyme Kinetic Parameters

kcat Value (Turnover Number) (3 results)

EC NUMBER
TURNOVER NUMBER [1/S]
TURNOVER NUMBER MAXIMUM [1/S]
COMMENTARY
LITERATURE
3.4
-
pH 6.5, 60°C

KM Value (3 results)

EC NUMBER
KM VALUE [MM]
KM VALUE MAXIMUM [MM]
COMMENTARY
LITERATURE
0.31
-
pH 6.5, 60°C

Ki Value (6 results)

EC NUMBER
KI VALUE [MM]
KI VALUE MAXIMUM [MM]
COMMENTARY
LITERATURE
5
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at pH 7.5 and 25°C, with furylacryloyl-glycyl-L-leucyl-L-alanine as substrate

References & Links

Links to other databases for benzyloxycarbonyl-Phe

ChEBI
PubChem
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PubChem