Ligand D-mannitol 1-phosphate

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Basic Ligand Information

Molecular Structure
Picture of D-mannitol 1-phosphate (click for magnification)
Molecular Formula
BRENDA Name
InChIKey
C6H15O9P
D-mannitol 1-phosphate
GACTWZZMVMUKNG-KVTDHHQDSA-N
Synonyms:
D-mannitol-1-phosphate, D-mannitol-6-phosphate, D-mannitol 1-phosphate[side 2], D-mannitol 6-phosphate, D-mannitol phosphate, mannitol-1-phosphate, mannitol 1-phosphate, mannitol 6-phosphate


Show all pahtways known for Show all BRENDA pathways known for D-mannitol 1-phosphate

Roles as Enzyme Ligand

In Vivo Substrate in Enzyme-catalyzed Reactions (6 results)

EC NUMBER
PROVEN IN VIVO REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
D-mannitol 1-phosphate + NADP+ = D-mannose 6-phosphate + NADPH + H+
show the reaction diagram
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[protein]-L-histidine + D-mannitol 1-phosphate[side 2] = [protein]-Npi-phospho-L-histidine + D-mannitol[side 1]
show the reaction diagram
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In Vivo Product in Enzyme-catalyzed Reactions (7 results)

EC NUMBER
PROVEN IN VIVO REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
D-mannose 6-phosphate + NADPH = D-mannitol 1-phosphate + NADP+
show the reaction diagram
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Substrate in Enzyme-catalyzed Reactions (18 results)

EC NUMBER
REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
mannitol 1-phosphate + NAD+ = ?
show the reaction diagram
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D-mannitol 1-phosphate + NADP+ = D-mannose 6-phosphate + NADPH + H+
show the reaction diagram
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[protein]-L-histidine + D-mannitol 1-phosphate[side 2] = [protein]-Npi-phospho-L-histidine + D-mannitol[side 1]
show the reaction diagram
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D-mannitol 6-phosphate + H2O = D-mannitol + phosphate
show the reaction diagram
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mannitol 1-phosphate + H2O = mannitol + phosphate
show the reaction diagram
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mannitol-1-phosphate + H2O = D-mannitol + phosphate
show the reaction diagram
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Product in Enzyme-catalyzed Reactions (10 results)

EC NUMBER
REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
phosphohistidinoprotein + D-mannitol = histidine-containing protein + D-mannitol phosphate
show the reaction diagram
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Inhibitor in Enzyme-catalyzed Reactions (8 results)

EC NUMBER
COMMENTARY
LITERATURE
ENZYME 3D STRUCTURE
competitive inhibition with respect to D-fructose 6-phosphate, noncompetitive inhibition with respect to NADH
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strong substrate inhibition at pH 7.0
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Enzyme Kinetic Parameters

kcat Value (Turnover Number) (4 results)

EC NUMBER
TURNOVER NUMBER [1/S]
TURNOVER NUMBER MAXIMUM [1/S]
COMMENTARY
LITERATURE
0.015
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at pH 7.5 and 30°C

KM Value (22 results)

EC NUMBER
KM VALUE [MM]
KM VALUE MAXIMUM [MM]
COMMENTARY
LITERATURE
45
-
-
50
-
-
0.82
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References & Links

Links to other databases for D-mannitol 1-phosphate

ChEBI
PubChem
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PubChem