Ligand pantothenate

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Basic Ligand Information

Molecular Structure
Picture of pantothenate (click for magnification)
Molecular Formula
BRENDA Name
InChIKey
C9H17NO5
pantothenate
GHOKWGTUZJEAQD-ZETCQYMHSA-N
Synonyms:
(R)-pantothenate, D-pantothenate, pantothenic acid


Show all pahtways known for Show all BRENDA pathways known for pantothenate

Roles as Enzyme Ligand

In Vivo Substrate in Enzyme-catalyzed Reactions (53 results)

EC NUMBER
PROVEN IN VIVO REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
pantothenic acid + H2O = ?
show the reaction diagram
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In Vivo Product in Enzyme-catalyzed Reactions (5 results)

EC NUMBER
PROVEN IN VIVO REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
ATP + (R)-pantoate + beta-alanine = AMP + diphosphate + (R)-pantothenate
show the reaction diagram
ATP + (R)-pantoate + beta-alanine = ADP + phosphate + (R)-pantothenate
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Substrate in Enzyme-catalyzed Reactions (278 results)

EC NUMBER
REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
ATP + pantothenate = ADP + 4'-phosphopantothenate
show the reaction diagram
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Product in Enzyme-catalyzed Reactions (20 results)

EC NUMBER
REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
ketopantoate + ? = pantothenate + ?
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pantetheine + O2 = pantothenate + cysteamine
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ATP + (R)-pantoate + beta-alanine = ADP + phosphate + (R)-pantothenate
show the reaction diagram
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Activator in Enzyme-catalyzed Reactions (1 result)

EC NUMBER
COMMENTARY
LITERATURE
ENZYME 3D STRUCTURE
contains 3.5 mol pantothenate per mol of enzyme in the acyl-carrier-protein gamma-subunit
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Inhibitor in Enzyme-catalyzed Reactions (19 results)

EC NUMBER
COMMENTARY
LITERATURE
ENZYME 3D STRUCTURE
0.5 mM or above
-
50 mM, 60% inhibition
-
strong product inhibition
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3D Structure of Enzyme-Ligand-Complex (PDB) (14 results)

Enzyme Kinetic Parameters

kcat Value (Turnover Number) (9 results)

EC NUMBER
TURNOVER NUMBER [1/S]
TURNOVER NUMBER MAXIMUM [1/S]
COMMENTARY
LITERATURE
0.21
-
42°C

KM Value (39 results)

EC NUMBER
KM VALUE [MM]
KM VALUE MAXIMUM [MM]
COMMENTARY
LITERATURE
1.3
-
42°C

Ki Value (3 results)

EC NUMBER
KI VALUE [MM]
KI VALUE MAXIMUM [MM]
COMMENTARY
LITERATURE

References & Links

Links to other databases for pantothenate

ChEBI
PubChem
ChEBI
PubChem