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-
Molecular weight estimations of some pyrimidine-metabolizing enzymes from pea cotyledons by gel filtration
1971
Murray, M.G.; Ross, C.
Phytochemistry
10
2645-2648
Inhibitors of glyoxalase enzymes
1980
Oray, B.; Norton, S.J.
Biochem. Biophys. Res. Commun.
95
624-629
-
Manganese-dependent production, and properties, of 5'-nucleotidase by alkalophilic Bacillus No. A-59
1989
Ikura, Y.; Horikoshi, K.
Agric. Biol. Chem.
53
645-649
High Km soluble 5'-nucleotidase from human placenta. Properties and allosteric regulation by IMP and ATP
1988
Spychala, J.; Madrid-Marina, V.; Fox, I.H.
J. Biol. Chem.
263
18759-18765
Purification of bovine liver cytosolic 5'-nucleotidase. Kinetic and structural studies as compared to the membrane isoenzyme
1988
Zekri, M.; Harb, J.; Bernard, S.; Meflah, K.
Eur. J. Biochem.
172
93-99
Properties of the membrane-bound 5'-nucleotidase and utilization of extracellular ATP in Vibrio parahaemolyticus
1987
Sakai, Y.; Toda, K.; Mitani, Y.; Tsuda, M.; Shinoda, S.; Tsuchiya, T.
J. Gen. Microbiol.
133
2751-2757
Purification, characterization and cellular localization of 5'-nucleotidase from Torpedo electric organ
1987
Grondal, E.J.M.; Zimmermann, H.
Biochem. J.
245
805-810
Properties of cytosol 5-nucleotidase and its role in purine nucleotide metabolism
1986
Tsushima, K.
Adv. Enzyme Regul.
25
181-200
-
Purification and properties of 5'-nucleotidase from cod muscle
1986
Yamamoto, H.; Tomioka, K.; Kawai, H.; Endo, K.
Agric. Biol. Chem.
50
1123-1129
-
Purification and characterization of a 5'-nucleotidase from Zea mays microsomes
1986
Carter, S.G.; Tipton, C.L.
Phytochemistry
25
33-37
Human placental cytoplasmic 5'-nucleotidase. Kinetic properties and inhibition
1986
Madrid-Marina, V.; Fox, I.H.
J. Biol. Chem.
261
444-452
Isolation and kinetic properties of 5'-nucleotidase from guinea-pig skeletal muscle
1985
Camici, M.; Fini, C.; Ipata, P.L.
Biochim. Biophys. Acta
840
6-12
-
Purification and some properties of an extracellular halophilic 5'-nucleotidase from a moderate halophile, Micrococcus varians subsp. Halophilus
1984
Onishi, H.; Kobayashi, T.; Kamekura, M.
FEMS Microbiol. Lett.
24
303-306
Purification and properties of bovine liver plasma membrane 5' nucleotidase
1983
Harb, J.; Meflah, K.; Duflos, Y.; Bernard, S.
Eur. J. Biochem.
137
131-138
5'-Nucleotidase from rat heart
1981
Naito, Y.; Lowenstein, J.M.
Biochemistry
20
5188-5194
Purification and properties of 5'-nucleotidase from the membrane of Vibrio costicola, a moderately halophilic bacterium
1981
Bengis-Garber, C.; Kushner, D.J.
J. Bacteriol.
146
24-32
Purification and some properties of cytosol 5'-nucleotidase from rat liver
1981
Itoh, R.
Biochim. Biophys. Acta
657
402-410
Kinetic properties of cytosol 5'-nucleotidase from chicken liver
1978
Itoh, R.; Usami, C.; Nishino, T.; Tsushima, K.
Biochim. Biophys. Acta
526
154-162
Purification of rat liver 5'-nucleotidase as a complex with sphingomyelin
1974
Widnell, C.C.
Methods Enzymol.
32
368-374
-
A 5'-nucleotidase from Neurospora crassa
1974
Olson, A.C.; Fraser, M.J.
Biochim. Biophys. Acta
334
156-167
Properties of a 5'-nucleotidase purified from mouse liver plasma membranes
1973
Evans, W.H.; Gurd, J.W.
Biochem. J.
133
189-199
Properties of 5'-nucleotidase from avian heart
1972
Gibson, W.B.; Drummond, G.I.
Biochemistry
11
223-229
-
Nucleotide phosphomonoesterases
1971
Drummond, G.I.; Yamamoto, M.
The Enzymes, 3rd Ed. (Boyer, P. D. , ed. )
4
337-354
-
Purification to homogeneity and characterization of plasma membrane and Golgi apparatus-specific 5'-adenosine monophosphatases from peanut cotyledons
1996
Gupta, A.; Sharma, C.B.
Plant Sci.
117
65-74
Isolation and characterization of the ecto-5'-nucleotidase from a rat glioblastoma cell line
1992
Turnay, J.; Olmo, N.; Navarro, J.M.; Gavilanes, J.G.; Lizarbe, M.A.
Mol. Cell. Biol.
117
23-33
Purification and properties of membrane-bound 5'-nucleotidase from black rockfish (Sebastes inermis) muscle
1993
Marseno, D.W.; Hori, K.; Miyazawa, K.
J. Agric. Food Chem.
41
863-869
Purification and properties of cytosol 5'-nucleotidase from black rockfish (Sebastes inermis) muscle
1993
Marseno, D.W.; Hori, K.; Miyazawa, K.
J. Agric. Food Chem.
41
1208-1212
Soluble 5'-nucleotidase from thyroid gland partial purification and properties
1996
Niedzwiecka, J.; Jaroszewicz, L.
Biochem. Biophys. Res. Commun.
221
471-476
Purification and characterization of 5'-nucleotidase/FAD pyrophosphatase from human placenta
1997
Lee, R.S.F.; Ford, H.C.
Methods Enzymol.
280
424-436
Partial purification and properties of an AMP-specific 5'-nucleotidase from pigeon heart
1990
Skladanowski, A.C.; Newby, A.C.
Biochem. J.
268
117-122
A low-Km 5'-nucleotidase from rat brain cytosolic fraction: purification, kinetic properties, and description of regulation by a novel factor that increases sensitivity to inhibition by ATP and ADP
1996
Orford, M.R.; Saggerson, E.D.
J. Neurochem.
67
795-804
A comparison of the properties of 5'-nucleotidase purified from the cytosolic and synaptic plasma membrane fractions of rat forebrain
1991
Lai, K.M.; Wong, P.C.L.
Int. J. Biochem.
23
1123-1130
Biochemical properties of 5'-nucleotidase from mouse skeletal muscle
1998
Martinez-Martinez, A.; Flores-Flores, C.; Campoy, F.J.; Munoz-Delgado, E.; Fini, C.; Vidal, C.J.
Biochim. Biophys. Acta
1386
16-28
-
High-performance liquid chromatographic assay of potato tuber 3'-nucleotidase
1987
Nguyen, T.T.; Palcic, M.M.; Hadziyev, D.
J. Chromatogr.
391
257-265
-
Purification and characterization of nucleases from tea leaves
1982
Imagawa, H.; Toryu, H.; Ozawa, T.; Takino, Y.
Agric. Biol. Chem.
46
1261-1269
Studies on 3-nucleotidase-nuclease from potato tubers. II. Further studies on substrate specificity and mode of action
1973
Suno, M.; Nomura, A.; Mizuno, Y.
J. Biochem.
73
1291-1297
Purification and properties of 3'-nucleotidase of Leishmania donovani
1992
Gbenle, G.O.; Dwyer, D.M.
Biochem. J.
285
41-46
An inducible 3'-nucleotidase/nuclease from the trypanosomatid Crithidia luciliae. Purification and characterization
1990
Neubert, T.A.; Gottlieb, M.
J. Biol. Chem.
265
7236-7242
Characterization of a filtrable 3'-nucleotidase of Leishmania donovani
1993
Gbenle, G.O.
Biochim. Biophys. Acta
1203
162-167
Purification and characterization of 3'-nucleotidase/nuclease from promastigotes of Leishmania donovani
1991
Campbell, T.A.; Zlotnick, G.W.; Neubert, T.A.; Sacci, J.B.; Gottlieb, M.
Mol. Biochem. Parasitol.
47
109-117
Purification and chacterization of a nuclease (3'-nucleotidase) from Penicillium sp.
1990
Kazama, H.; Tabat, N.; Ohgi, K.; Irie, M.
Chem. Pharm. Bull.
38
3081-3085
Further studies on the specificity of the minor ribonuclease from Aspergillus saitoi
1976
Irie, M.; Ohgi, K.
J. Biochem.
80
39-43
Periplasmic nonspecific acid phosphatase II from Salmonella typhimurium LT2. Crystallization, detergent reactivation, and phosphotransferase activity
1988
Uerkvitz, W.
J. Biol. Chem.
263
15823-15830
S1 nuclease of Aspergillus oryzae: characterization of the associated phosphomonoesterase activity
1981
Oleson, A.E.; Hoganson, E.D.
Arch. Biochem. Biophys.
211
478-484
-
Single-strand-specific nucleases
1982
Shishido, K.; Ando, T.
Cold Spring Harbor Monogr. Ser.
14
155-185
S1 nuclease of Aspergillus oryzae: a glycoprotein with an associated nucleatidase activity
1980
Oleson, A.E.; Sasakuma, M.
Arch. Biochem. Biophys.
204
361-370
Studies of the 2:3-cyclic nucleotide phosphodiesterase of Haemophilus influenzae
1985
Anderson, B.M.; Kahn, D.W.; Anderson, C.D.
J. Gen. Microbiol.
131
2041-2045
Cytidine 5-monophosphosialic acid hydrolase. Subcellular location and properties
1974
Kean, E.L.; Bighouse, K.J.
J. Biol. Chem.
249
7813-7823
-
Nature of enzymes that catalyze the cleavage of the N-glycosidic bond of pyrimidine ribonucleosides in some filamentous fungi
1987
Allam, A.M.; Hassan, M.M.; Ghanem, B.S.; Elzainy, T.A.
Biochem. Syst. Ecol.
15
515-517
-
Purine salvage enzymes in man and Leishmania donovani
1980
Krenitsky, T.A.; Koszalka, G.W.; Tuttle, J.V.; Adamczyk, D.L.; Elion, G.B.; Marr, J.J.
Adv. Exp. Med. Biol.
122
51-56
Nucleosidases from Leishmania donovani. Pyrimidine ribonucleosidase, purine ribonucleosidase, and a novel purine 2-deoxyribonucleosidase
1979
Koszalka, G.W.; Krenitsky, T.A.
J. Biol. Chem.
254
8185-8193
Purification and properties of nucleoside hydrolase from Pseudomonas fluorescens
1967
Terada, M.; Tatibana, M.; Hayaishi, O.
J. Biol. Chem.
242
5578-5585
Partial purification and characterization of S-adenosylhomocysteine hydrolase isolated from Saccharomyces cerevisiae
1972
Knudsen, R.C.; Yall, I.
J. Bacteriol.
112
569-575
-
La desoxycytidine aminohydrolase des feuilles de Zea mays
1974
Le Floc`h, F.; Guillot, A.
Phytochemistry
13
2503-2509
The role of deoxycytidine-metabolizing enzymes in the cytotoxicity induced by 3'-amino-2',3'-dideoxycytidine and cytosine arabinoside
1992
Mancini, W.R.
Cancer Chemother. Pharmacol.
30
139-144
Role of deoxycytidine kinase (dCK), thymidine kinase 2 (TK2), and deoxycytidine deaminase (dCDA) in the antitumour activity of gemcitabine (dFdC)
1998
Kroep, J.R.; van Moorsel, C.J.A.; Veerman, G.; Voorn, D.A.; Schultz, R.M.; Worzalla, J.F.; Tanzer, L.R.; Merriman, R.L.; Pinedo, H.M.; Peters, G.J.
Adv. Exp. Med. Biol.
431
657-660
-
Guanosine deaminase and guanine deaminase from tea leaves
1994
Negishi, O.; Ozawa, T.; Imagawa, H.
Biosci. Biotechnol. Biochem.
58
1277-1281
Cytidine deaminase from Escherichia coli. Purification, properties and inhibition by the potential transition state analog 3,4,5,6-tetrahydrouridine
1971
Cohen, R.M.; Wolfenden, R.
J. Biol. Chem.
246
7561-7565
The purification and properties of cytidine deaminase from Escherichia coli
1973
Hosono, H.; Kuno, S.
J. Biochem.
74
797-803
On the interaction of 3,4,5,6-tetrahydrouridine with human liver cytidine deaminase
1975
Wentworth, D.F.; Wolfenden, R.
Biochemistry
14
5099-5105
The action of bacterial cytidine deaminase on 5,6-dihydrocytidine
1975
Evans, B.E.; Mitchell, G.N.; Wolfenden, R.
Biochemistry
14
621-624
Cytidine deaminases (from Escherichia coli and human liver)
1978
Wentworth, D.F.; Wolfenden, R.
Methods Enzymol.
51
401-407
Characteristics of cytidine aminohydrolase activity in Trypanosoma cruzi and Crithidia fasciculata
1984
Kidder, G.W.
J. Protozool.
31
298-300
Cytidine deaminase from Escherichia coli B. Purification and enzymatic and molecular properties
1985
Vita, A.; Amici, A.; Cacciamani, T.; Lanciotti, M.; Magni, G.
Biochemistry
24
6020-6024
-
Preparation of analogues of cytosine and 2-pyrimidinone nucleosides and their effect on bacterial (Escherichia coli A19) cytidine aminohydrolase
1985
Holy, A.; Ludzisa, A.; Votruba, I.; Sediva, K.
Collect. Czech. Chem. Commun.
50
393-417
On the role of cytidine deaminase in cellular metabolism
1986
Nygaard, P.
Adv. Exp. Med. Biol.
195B
415-420
-
Purification and properties of Escherichia coli cytidine deaminase by amplification of the cdd gene
1991
Kwon, T.K.; Lee, S.Y.; Kim, J.G.; Song, B.H.; Hong, S.D.
Mol. Cells
1
281-286
Purification of human cytidine deaminase: Molecular and enzymatic characterization and inhibition by synthetic pyrimidine analogs
1991
Cacciamani, T.; Vita, A.; Cristalli, G.; Vincenzetti, S.; Natalini, P.; Ruggieri, S.; Amici, A.; Magni, G.
Arch. Biochem. Biophys.
290
285-292
Recombinant human cytidine deaminase: Expression, purification, and characterization
1996
Vincenzetti, S.; Cambi, A.; Neuhard, J.; Garattini, E.; Vita, A.
Protein Expr. Purif.
8
247-253
Cloning, expression, and purification of cytidine deaminase from Arabidopsis thaliana
1999
Vincenzetti, S.; Cambi, A.; Neuhard, J.; Schnorr, K.; Grelloni, M.; Vita, A.
Protein Expr. Purif.
15
8-15
A prokaryotic-type cytidine deaminase from Arabidopsis thaliana gene expression and functional characterization
1999
Faivre-Nitschke, E.; Grienenberger, J.M.; Gualberto, J.M.
Eur. J. Biochem.
263
896-903
Purification and properties of a unique nucleotide pyrophosphatase/phosphodiesterase I that accumulates in soybean leaves in response to fruit removal
1995
Salvucci, M.E.; Crafts-Brandner, S.J.
Plant Physiol.
108
1269-1276
Novel activity of potato nucleotide pyrophosphatase
1976
Kole, R.; Sierakowska, H.; Shugar, D.
Biochim. Biophys. Acta
438
540-550
-
Properties of a new enzyme, nucleoside oxidase, from Pseudomonas maltophilia LB-86
1989
Isono, Y.; Sudo, T.; Hoshino, M.
Agric. Biol. Chem.
53
1671-1677
Nuceloside oxidase, a hydrogen peroxide-forming oxidase, from Flavobacterium meningosepticum
1997
Koga, S.; Ogawa, J.; Cheng, L.Y.; Choi, Y.M.; Yamada, H.; Shimizu, S.
Appl. Environ. Microbiol.
63
4282-4286
-
Purification and properties of purine nucleosidase from N2-fixing nodules of cowpea (Vigna unguiculata)
1989
Atkins, C.A.; Shelp, B.J.; Storer, P.J.
J. Plant Physiol.
134
447-452
Nucleoside hydrolase from Crithidia fasciculata. Metabolic role, purification, specificity, and kinetic mechanism
1991
Parkin, D.W.; Horenstein, B.A.; Abdulah, D.R.; Estupinan, B.; Schramm, V.L.
J. Biol. Chem.
266
20658-20665
Purine-specific nucleoside N-ribohydrolase from Trypanosoma brucei brucei
1996
Parkin, D.W.
J. Biol. Chem.
271
21713-21719
Purification and properties of a bacterial riboside riboside hydrolase
1956
Takagi, Y.; Horecker, B.L.
J. Biol. Chem.
225
77-86
-
Uridine nucleosidase from malt
1987
Lee, W.J.
J. Am. Soc. Brew. Chem.
45
131-135
Uridine nucleosidase from yeast
1978
Magni, G.
Methods Enzymol.
51
290-296
Baker's yeast uridine nucleosidase is a regulatory copper containing protein
1976
Magni, G.; Natalini, P.; Ruggieri, S.; Vita, A.
Biochem. Biophys. Res. Commun.
69
724-730
Baker's yeast uridine nucleosidase. II. Enzymatic and kinetic properties
1974
Vita, A.; Natalini, P.; Ipata, P.L.; Magni, G.
Boll. Soc. Ital. Biol. Sper.
50
1077-1083
Baker's yeast uridine nucleosidase. I. Purification to homogeneity
1974
Corradetti, E.; Natalini, P.; Ipata, P.L.; Magni, G.
Boll. Soc. Ital. Biol. Sper.
50
1070-1076
Bakers yeast uridine nucleosidase. Purification, composition, and physical and enzymatic properties
1975
Magni, G.; Fioretti, E.; Ipata, P.L.; Natalini, P.
J. Biol. Chem.
250
9-13
Partial purification and properties of uridine nucleosidase from Baker's yeast
1971
Raggi-Ranieri, M.; Ipata, P.L.
Ital. J. Biochem.
20
27-43
Purification and properties of uridine hydrolase from mung-bean (Phaseolus radiatus) seedlings
1967
Achar, B.S.; Vaidyanathan, C.S.
Arch. Biochem. Biophys.
119
356-362
New insights into the pyrimidine salvage pathway of Saccharomyces cerevisiae: requirement of six genes for cytidine metabolism
1999
Kurtz, J.E.; Exinger, F.; Erbs, P.; Jund, R.
Curr. Genet.
36
130-136
Polyol metabolism by a caries-conductive Streptococcus: Purification and properties of a nicotinamide adenine dinucleotide-dependent mannitol-1-phosphate dehydrogenase
1977
Brown, A.T.; Bowles, R.D.
Infect. Immun.
16
163-173
Identification of two alpha-ketoglutarate-dependent dioxygenases in extracts of Rhodotorula glutinis catalyzing deoxyuridine hydroxylation
1985
Stubbe, J.
J. Biol. Chem.
260
9972-9975
Purification, properties and partial amino acid sequence of the blood-group-A-gene-associated alpha-3-N-acetylgalactosaminyltransferase from human gut mucosal tissue
1990
Navaratnam, N.; Findlay, J.B.C.; Keen, J.N.; Watkins, W.M.
Biochem. J.
271
93-98
Solubilization and partial characterization of UDP-N-acetylgalactosamine: globoside alpha-N-acetylgalactosaminyltransferase from dog spleen microsomes
1977
Ishibashi, T.; Ohkubo, I.; Makita, A.
Biochim. Biophys. Acta
484
24-34
Effects of uridine nucleotides and nucleotide pyrophosphatase on glycolipid alpha and beta-N-acetylgalactosaminyltransferase activities in guinea pig microsomes
1976
Ishibashi, T.; Atsuta, T.; Makita, A.
Biochim. Biophys. Acta
429
759-767
-
Properties of nucleoside phosphorylase from Enterobacter aerogenes
1985
Utagawa, T.; Morisawa, H.; Yamanaka, S.; Yamazaki, A.; Yoshinaga, F.; Hirose, Y.
Agric. Biol. Chem.
49
3239-3246
Purification and characterization of purine nucleoside phosphorylase and pyrimidine nucleoside phosphorylase from Bacillus stearothermophilus TH 6-2
1996
Hamamoto, T.; Noguchi, T.; Midorikawa, Y.
Biosci. Biotechnol. Biochem.
60
1179-1180
Orotate phosphoribosyltransferase: orotidylate decarboxylase (Ehrlich ascites cell)
1978
Jones, M.E.; Kavipurapu, P.R.; Traut, T.W.
Methods Enzymol.
51
155-167
Functional expression of a multisubstrate deoxyribonucleoside kinase from Drosophila melanogaster and its C-terminal deletion mutants
2000
Munch-Petersen, B.; Knecht, W.; Lenz, C.; Sondergaard, L.; Piskur, J.
J. Biol. Chem.
275
6673-6679
Identification of residues involved in the specificity and regulation of the highly efficient multisubstrate deoxyribonucleoside kinase from Drosophila melanogaster
2000
Knecht, W.; Munch-Petersen, B.; Piskur, J.
J. Mol. Biol.
301
827-837
Deoxyribosyl transfer. I. Thymidine phosphorylase and nucleoside deoxyribosyltransferase in normal and malignant tissues
1964
Zimmerman, M.; Seidenberg, J.
J. Biol. Chem.
239
2618-2621
Purification and characterization of uridine (thymidine) phosphorylase from Giardia lamblia
1988
Lee, C.S.; Jimenez, B.M.; O'Sullivan, W.J.
Mol. Biochem. Parasitol.
30
271-287
Partial purification of a thymidine phosphorylase from human gastric cancer
1986
Sugata, S.; Kono, A.; Hara, Y.; Karube, Y.; Matsushima, Y.
Chem. Pharm. Bull.
34
1219-1222
Purification and properties of thymidine phosphorylase from Salmonella typhimurium
1975
Blank, J.G.; Hoffee, P.A.
Arch. Biochem. Biophys.
168
259-265
Purification and characterization of uridine and thymidine phosphorylase from Lactobacillus casei
1990
Avraham, Y.; Grossowicz, N.; Yashphe, J.
Biochim. Biophys. Acta
1040
287-293
-
Thymidine phosphorylase and uridine phosphorylase of Lactobacillus casei
1988
Avraham, Y.; Yashphe, J.; Grossowicz, N.
FEMS Microbiol. Lett.
56
29-34
Differences in activities and substrate specificity of human and murine pyrimidine nucleoside phosphorylases: implications for chemotherapy with 5-fluoropyrimidines
1993
el Kouni, M.H.; el Kouni, M.M.; Naguib, F.N.
Cancer Res.
53
3687-3693
Expression, characterization, and detection of human uridine phosphorylase and identification of variant uridine phosphorolytic activity in selected human tumors
1998
Liu, M.; Cao, D.; Russell, R.; Handschumacher, R.E.; Pizzorno, G.
Cancer Res.
58
5418-5424
Uridine and deoxyuridine phosphorylases from Ehrlich ascites tumor
1961
Pontis, H.; Degerstedt, G.; Reichard, P.
Biochim. Biophys. Acta
51
138-147
Pyrimidine metabolism. II. Enzymatic pathways of uracil anabolism
1957
Canellakis, E.S.
J. Biol. Chem.
227
329-338
Pyrimidine acyclonucleosides, inhibitors of uridine phosphorylase
1981
Niedzwicki, J.G.; El Kouni, M.H.; Chu, S.H.; Cha, S.
Biochem. Pharmacol.
30
2097-2101
Uridine phosphorylase from Novikoff rat hepatoma cells: purification, kinetic properties, and its role in uracil anabolism
1985
McIvor, R.S.; Wohlhueter, R.M.; Plagemann, P.P.G.
J. Cell. Physiol.
122
397-404
New analogues of benzylacyclouridines, specific and potent inhibitors of uridine phosphorylase from human and mouse livers
1987
Naguib, F.N.M.; El Kouni, M.H.; Chu, S.H.; Cha, S.
Biochem. Pharmacol.
36
2195-2201
-
Purification and kinetic characterization of uridine phosphorylase from Dictyostelium discoiderm
1989
Albe, K.R.; Wright, B.E.
Exp. Mycol.
13
13-19
Uridine phosphorylase from Escherichia coli B.: kinetic studies on the mechanism of catalysis
1983
Vita, A.; Huang, C.Y.; Magni, G.
Arch. Biochem. Biophys.
226
687-692
Uridine phosphorylase from Escherichia coli. Kinetic properties and mechanism
1976
Krenitsky, T.A.
Biochim. Biophys. Acta
429
352-358
-
Acyclonucleoside analogues consisting of 5- and 5,6-substituted uracils and different acylic chains: inhibitory properties vs purified E. coli uridine phosphorylase
1987
Drabikowska, A.K.; Lissowska, L.; Draminski, M.; Zgit-Wroblewska, L.; Shugar, D.
Z. Naturforsch. C
42c
288-296
Uridine phosphorylase from rat liver
1978
Yamada, E.W.
Methods Enzymol.
51
423-431
Uridine phosphorylase from Escherichia coli. Physical and chemical characterization
1977
Leer, J.C.; Hammer-Jespersen, K.; Schwartz, M.
Eur. J. Biochem.
75
217-224
Uridine phosphorylase from Schistosoma mansoni
1988
El Kouni, M.H.; Fardos, N.M.; Naguib, F.N.M.; Niedzwicki, J.G.; Iltzsch, M.H.; Cha, S.
J. Biol. Chem.
263
6081-6086
Purification and substrate specificity of pyrimidine nucleoside phosphorylase from Haemophilus influenzae
1971
Scocca, J.J.
J. Biol. Chem.
246
6606-6610
Uridine phosphorylase from Acholeplasma laidlawii: purification and kinetic properties
1983
McIvor, R.S.; Wohlhueter, R.M.; Plagemann, P.G.W.
J. Bacteriol.
156
198-204
Uridine phosphorylase from Hymenolepis diminuta (Cestoda): kinetics and inhibition by pyrimidine nucleoside analogs
1996
Drabikowska, A.K.
Acta Biochim. Pol.
43
733-741
Complete inactivation of Escherichia coli uridine phosphorylase by modification of Asp5 with Woodward's reagent K
1995
Komissarov, A.A.; Romanova, D.V.; Debabov, V.G.
J. Biol. Chem.
270
10050-10055
Saccharomyces cerevisiae URH1 (encoding uridine-cytidine N-ribohydrolase): functional complementation by a nucleoside hydrolase from a protozoan parasite and by a mammalian uridine phosphorylase
2002
Mitterbauer, R.; Karl, T.; Adam, G.
Appl. Environ. Microbiol.
68
1336-1343
Isolation and initial characterization of the uridine phosphorylase from Salmonella typhimurium
1998
Molchan, O.K.; Dmitrieva, N.A.; Romanova, D.V.; Lopes, L.E.; Debabov, V.G.; Mironov, A.S.
Biochemistry (Moscow)
63
195-199
Uridine phosphorylase association with vimentin. Intracellular distribution and localization
2001
Russell, R.L.; Cao, D.; Zhang, D.; Handschumacher, R.E.; Pizzorno, G.
J. Biol. Chem.
276
13302-13307
Purification, cloning, and expression of murine uridine phosphorylase
1995
Watanabe, S.; Hino, A.; Wada, K.; Eliason, J.F.; Uchida, T.
J. Biol. Chem.
270
12191-12196
An intestinal phosphorylase for uric ribonucleoside
1963
Laster, L.; Blair, A.
J. Biol. Chem.
238
3348-3357
Purification and comparative properties of a pyrimidine nucleoside phosphorylase from Bacillus stearothermophilus
1969
Saunders, P.P.; Wilson, B.A.; Saunders, G.F.
J. Biol. Chem.
244
3691-3697
The crystal structure of pyrimidine nucleoside phosphorylase in a closed conformation
1998
Pugmire, M.J.; Ealick, S.E.
Structure
6
1467-1479
Pyrimidine nucleoside phosphorylase from Haemophilus influenzae
1978
Scocca, J.J.
Methods Enzymol.
51
432-437
-
Purification and characterization of thermostable pyrimidine nucleoside phosphorylase from Bacillus stearothermophilus
1990
Hori, N.; Watanabe, M.; Yamazaki, Y.; Mikami, Y.
Agric. Biol. Chem.
54
763-768
-
Bacterial synthesis of nucleosides by the pentosyl transfer reaction from nucleoside to base
1973
Kamimura, A.; Mitsugi, K.; Okumura, S.
Agric. Biol. Chem.
37
2063-2072
Thymidine phosphotransferase and nucleotide phosphohydrolase of the fern Asplenium nidus. General properties and inhibition by adenosine 3:5-cyclic monophosphate
1976
Grivell, A.R.; Jackson, J.F.
Biochem. J.
155
571-581
Human placental adenosine kinase. Kinetic mechanism and inhibition
1980
Palella, T.D.; Andres, C.M.; Fox, I.H.
J. Biol. Chem.
255
5264-5269
Isolation and characterization of adenosine kinase from Leishmania donovani
1987
Datta, A.K.; Bhaumik, D.; Chatterjee, R.
J. Biol. Chem.
262
5515-5521
Expression, purification and characterization of recombinant Saccharomyces cerevisiae adenosine kinase
2003
Xiao-Bing, L.V.; Hai-Zhen, W.U.; Jiang, Y.E.; Yi, F.; Hui-Zhan, Z.
Acta Biochim. Biophys. Sin.
35
666-670
-
Uridine kinase from ehrlich ascites tumor: purification and properties
1960
Sköld, O.
J. Biol. Chem.
235
3273-3279
Regulation of a thermostable pyrimidine ribonucleoside kinase by cytidine triphosphate
1972
Orengo, A.; Saunders, G.F.
Biochemistry
11
1761-1767
Properties of uridine-cytidine kinase derived from L1210 leukemia cells
1980
Ahmed, N.K.; Baker, D.R.
Cancer Res.
40
3559-3563
Characteristics of the enzyme uridine-cytidine kinase isolated from a cultured human cell line
1977
Drake, J.C.; Stoller, R.G.; Chabner, B.A.
Biochem. Pharmacol.
26
64-66
The partial purification and properties of uridine kinase from Ehrlich ascites tumor cells
1973
Krystal, G.; Scholefield, P.G.
Can. J. Biochem.
51
379-389
Uridine-cytidine kinase from Novikoff ascites rat tumor and Bacillus stearothermophilus
1978
Orengo, A.; Kobayashi, S.H.
Methods Enzymol.
51
299-307
Uridine-cytidine kinase from Escherichia coli
1978
Valentin-Hansen, P.
Methods Enzymol.
51
308-314
Uridine-cytidine kinase from a murine neoplasm
1978
Anderson, E.P.
Methods Enzymol.
51
314-321
Regulation of enzymic activity by metabolites. I. Uridine-cytidine kinase of Novikoff ascites rat tumor
1969
Orengo, A.
J. Biol. Chem.
244
2204-2209
Uridine kinase from Ehrlich ascites carcinoma. Purification and properties of homogeneous enzyme
1985
Payne, R.C.; Cheng, N.; Traut, T.W.
J. Biol. Chem.
260
10242-10247
Uridine--cytidine kinase from foetal and adult rat liver. Purification and study of some properties
1976
Fulchignoni-Lataud, M.C.; Tuilie, M.; Roux, J.M.
Eur. J. Biochem.
69
217-222
Uridine-cytidine kinase. Purification from a murine neoplasm and characterization of the enzyme
1975
Liacouras, A.S.; Anderson, E.P.
Arch. Biochem. Biophys.
168
66-73
Uridine-cytidine kinase. Kinetic studies and reaction mechanism
1975
Liacouras, A.S.; Garvey, T.Q.; Millar, F.K.; Anderson, E.P.
Arch. Biochem. Biophys.
168
74-80
Pb-precipitated protein fraction from calf brain containing highly active uridine kinase with different molecular properties
1975
Cihak, A.
FEBS Lett.
51
133-136
Stability of the insoluble form of uridine kinase coupled to Zn2+ or Pb2+ ions
1976
Cihak, A.
Hoppe-Seyler's Z. Physiol. Chem.
357
345-350
Increased uridine kinase (ATP: uridine 5'-phosphotransferase; EC 2.7.1.48) activity in human and rat tumors
1998
Shen, F.; Look, K.Y.; Yeh, Y.A.; Weber, G.
Cancer Biochem. Biophys.
16
1-15
Cloning and expression of uridine/cytidine kinase cDNA from human fibrosarcoma cells
2001
Koizumi, K.; Shimamoto, Y.; Azuma, A.; Wataya, Y.; Matsuda, A.; Sasaki, T.; Fukushima, M.
Int. J. Mol. Med.
8
273-278
Phosphorylation of uridine and cytidine nucleoside analogs by two human uridine-cytidine kinases
2001
Van Rompay, A.R.; Norda, A.; Linden, K.; Johansson, M.; Karlsson, A.
Mol. Pharmacol.
59
1181-1186
Purification and characterization of deoxycytidine kinase from acute myeloid leukemia cell mitochondria
1993
Wang, L.M.; Kucera, G.L.; Capizzi, R.L.
Biochim. Biophys. Acta
1202
309-316
Purification and properties of a nucleoside phosphotransferase from carrot
1967
Brunngraber, E.F.; Chargaff, E.
J. Biol. Chem.
242
4834-4840
Nucleoside phosphotransferase from carrot
1978
Brunngraber, E.F.
Methods Enzymol.
51
387-394
Nucleoside phosphotransferase from barley. Characterization and evidence for ping pong kinetics involving phosphoryl enzyme
1982
Prasher, D.C.; Carr, M.C.; Ives, D.H.; Tsai, T.C.; Frey, P.A.
J. Biol. Chem.
257
4931-4939
Nucleoside phosphotransferase from malt sprouts. I. Isolation, characterization and specificity of the enzyme
1986
Billich, A.; Stockhowe, U.; Witzel, H.
Biol. Chem. Hoppe-Seyler
367
267-278
Nucleoside phosphotransferase from yellow lupin seedling cotyledons
1979
Guranowski, A.
Biochim. Biophys. Acta
569
13-22
A novel selective nucleoside phosphorylating enzyme from Morganella morganii
1999
Asano, Y.; Mihara, Y.; Yamada, H.
J. Biosci. Bioeng.
87
732-738
-
Characterization of nucleoside phosphotransferase from Leishmania tropica
1995
Shin, I.S.; Wataya, Y.
Nucleosides Nucleotides
14
13-22
Inhibition of UDP-N-acetylglucosamine pyrophosphorylase by uridine
1980
Yamamoto, K.; Moriguchi, M.; Kawai, H.; Tochikura, T.
Biochim. Biophys. Acta
614
367-372
Occurrence of IMP-GMP 5'-nucleotidase in three fish species: a comparative study on Trachurus japonicus, Oncorhynchus masou masou and Triakis scyllium
2002
Itoh, R.; Kimura, K.
Comp. Biochem. Physiol. B
132
401-408
Human cytosolic 5'-nucleotidase I: characterization and role in nucleoside analog resistance
2001
Hunsucker, S.A.; Spychala, J.; Mitchell, B.S.
J. Biol. Chem.
276
10498-10504
Characterization of a cell-wall acid phosphatase (PhoAp) in Aspergillus fumigatus
2002
Bernard, M.; Mouyna, I.; Dubreucq, G.; Debeaupuis, J.P.; Fontaine, T.; Vorgias, C.; Fuglsang, C.; Latge, J.P.
Microbiology
148
2819-2829
The class C acid phosphatase of Helicobacter pylori is a 5' nucleotidase
2004
Reilly, T.J.; Calcutt, M.J.
Protein Expr. Purif.
33
48-56
Cloning, preliminary characterization and crystallization of nucleoside hydrolases from Caenorhabditis elegans and Campylobacter jejuni
2003
Versees, W.; van Holsbeke, E.; de Vos, S.; Decanniere, K.; Zegers, I.; Steyaert, J.
Acta Crystallogr. Sect. D
D59
1087-1089
Purification, characterization, and gene cloning of purine nucleosidase from Ochrobactrum anthropi
2001
Ogawa, J.; Takeda, S.; Xie, S.X.; Hatanaka, H.; Ashikari, T.; Amachi, T.; Shimizu, S.
Appl. Environ. Microbiol.
67
1783-1787
The URH1 uridine ribohydrolase of Saccharomyces cerevisiae
2002
Kurtz, J.E.; Exinger, F.; Erbs, P.; Jund, R.
Curr. Genet.
41
132-141
Structure and function of a novel purine specific nucleoside hydrolase from Trypanosoma vivax
2001
Versees, W.; Decanniere, K.; Pelle, R.; Depoorter, J.; Brosens, E.; Parkin, D.W.; Steyaert, J.
J. Mol. Biol.
307
1363-1379
Crystal structure to 1.7 ANG of the Escherichia coli pyrimidine nucleoside hydrolase YeiK, a novel candidate for cancer gene therapy
2004
Giabbai, B.; Degano, M.
Structure
12
739-749
Structural basis for inhibition of Escherichia coli uridine phosphorylase by 5-substituted acyclouridines
2005
Bu, W.; Settembre, E.C.; el Kouni, M.H.; Ealick, S.E.
Acta Crystallogr. Sect. D
61
863-872
Identification of a novel human uridine phosphorylase
2003
Johansson, M.
Biochem. Biophys. Res. Commun.
307
41-46
Synthesis and evaluation of 6-methylene-bridged uracil derivatives. Part 1: discovery of novel orally active inhibitors of human thymidine phosphorylase
2004
Yano, S.; Kazuno, H.; Suzuki, N.; Emura, T.; Wierzba, K.; Yamashita, J.; Tada, Y.; Yamada, Y.; Fukushima, M.; Asao, T.
Bioorg. Med. Chem.
12
3431-3441
-
Application of biocatalysts and biotransformation to the synthesis of pharmaceuticals
1997
Zaks, A.; Dodds, D.R.
Drug Discov. Today
2
513-531
-
Mutagenesis of Escherichia coli uridine phosphorylase by random pentapeptide insertions
2004
Oliva, I.; Zuffi, G.; Orsini, G.; Tonon, G.; de Gioia, L.; Ghisotti, D.
Enzyme Microb. Technol.
35
309-314
Identification of a liver-specific uridine phosphorylase that is regulated by multiple lipid-sensing nuclear receptors
2004
Zhang, Y.; Repa, J.J.; Inoue, Y.; Hayhurst, G.P.; Gonzalez, F.J.; Mangelsdorf, D.J.
Mol. Endocrinol.
18
851-862
Structure of human uridine-cytidine kinase 2 determined by SIRAS using a rotating-anode X-ray generator and a single samarium derivative
2005
Appleby, T.C.; Larson, G.; Cheney, I.W.; Walker, H.; Wu, J.Z.; Zhong, W.; Hong, Z.; Yao, N.
Acta Crystallogr. Sect. D
61
278-284
A crucial role of uridine/cytidine kinase 2 in antitumor activity of 3'-ethynyl nucleosides
2004
Murata, D.; Endo, Y.; Obata, T.; Sakamoto, K.; Syouji, Y.; Kadohira, M.; Matsuda, A.; Sasaki, T.
Drug Metab. Dispos.
32
1178-1182
Deoxyribonucleoside kinases belonging to the thymidine kinase 2 (TK2)-like group vary significantly in substrate specificity, kinetics and feed-back regulation
2002
Knecht, W.; Petersen, G.E.; Munch-Petersen, B.; Piskur, J.
J. Mol. Biol.
315
529-540
Mg2+ as activator of uridine phosphorylation in coordination with other cellular responses to growth factors
2005
Vidair, C.; Rubin, H.
Proc. Natl. Acad. Sci. USA
102
662-666
Structural basis for the specificity, catalysis, and regulation of human uridine-cytidine kinase
2004
Suzuki, N.N.; Koizumi, K.; Fukushima, M.; Matsuda, A.; Inagaki, F.
Structure
12
751-764
Cloning, purification, crystallization and X-ray analysis of the Escherichia coli pyrimidine nucleoside hydrolase YeiK
2004
Giabbai, B.; Degano, M.
Acta Crystallogr. Sect. D
60
524-527
New insight in to the mechanism of nucleoside hydrolases from crystal structure of the Escherichia coli YbeK protein bound to the reaction product
2006
Muzzolini, L.; Versees, W.; Tornaghi, P.; Van Holsbeke, E.; Steyaert, J.; Degano, M.
Biochemistry
45
773-782
Purification and characterization of RihC, a xanthosine-inosine-uridine-adenosine-preferring hydrolase from Salmonella enterica serovar Typhimurium
2005
Hansen, M.R.; Dandanell, G.
Biochim. Biophys. Acta
1723
55-62
Genes encoding ribonucleoside hydrolase 1 and 2 from Corynebacterium ammoniagenes
2006
Kim, H.S.; Lee, J.H.; Lee, W.S.; Bang, W.G.
Microbiology
152
1169-1177
Isoenzymatic forms of human cytidine deaminase
2004
Vincenzetti, S.; Mariani, P.L.; Cammertoni, N.; Polzonetti, V.; Natalini, P.; Quadrini, B.; Volpini, R.; Vita, A.
Protein Eng. Des. Sel.
17
871-877
Structure-activity relationship for nucleoside analogs as inhibitors or substrates of adenosine kinase from Mycobacterium tuberculosis. I. Modifications to the adenine moiety
2006
Long, M.C.; Parker, W.B.
Biochem. Pharmacol.
71
1671-1682
Substrate specificity of Escherichia coli thymidine phosphorylase
2007
Panova, N.G.; Alexeev, C.S.; Kuzmichov, A.S.; Shcheveleva, E.V.; Gavryushov, S.A.; Polyakov, K.M.; Kritzyn, A.M.; Mikhailov, S.N.; Esipov, R.S.; Miroshnikov, A.I.
Biochemistry
72
21-28
Unusual sugar nucleotide recognition elements of mesophilic vs. thermophilic glycogen synthases
2005
Zea, C.J.; Pohl, N.L.
Biopolymers
79
106-113
Metabolic effects of novel N-1-sulfonylpyrimidine derivatives on human colon carcinoma cells
2005
Glavas-Obrovac, L.; Karner, I.; Stefanic, M.; Kasnar-Samprec, J.; Zinic, B.
Farmaco
60
479-483
The role of thymidine phosphorylase and uridine phosphorylase in (fluoro)pyrimidine metabolism in peripheral blood mononuclear cells
2006
Temmink, O.H.; de Bruin, M.; Laan, A.C.; Turksma, A.W.; Cricca, S.; Masterson, A.J.; Noordhuis, P.; Peters, G.J.
Int. J. Biochem. Cell Biol.
38
1759-1765
Toxoplasma gondii purine nucleoside phosphorylase biochemical characterization, inhibitor profiles, and comparison with the Plasmodium falciparum ortholog
2006
Chaudhary, K.; Ting, L.M.; Kim, K.; Roos, D.S.
J. Biol. Chem.
281
25652-25658
Modulation of uridine phosphorylase gene expression by tumor necrosis factor-alpha enhances the antiproliferative activity of the capecitabine intermediate 5-deoxy-5-fluorouridine in breast cancer cells
2006
Wan, L.; Cao, D.; Zeng, J.; Yan, R.; Pizzorno, G.
Mol. Pharmacol.
69
1389-1395
Key role of uridine kinase and uridine phosphorylase in the homeostatic regulation of purine and pyrimidine salvage in brain
2007
Balestri, F.; Barsotti, C.; Lutzemberger, L.; Camici, M.; Ipata, P.L.
Neurochem. Int.
51
517-523
Evaluation of uridine metabolism in human and animal spermatozoa
2006
Niemeyer, T.; Dietz, C.; Fairbanks, L.; Schroeder-Printzen, I.; Henkel, R.; Loeeffler, M.
Nucleosides Nucleotides Nucleic Acids
25
1215-1219
Functional characterization of a gene encoding a dual domain for uridine kinase and uracil phosphoribosyltransferase in Arabidopsis thaliana
2007
Islam, M.R.; Kim, H.; Kang, S.W.; Kim, J.S.; Jeong, Y.M.; Hwang, H.J.; Lee, S.Y.; Woo, J.C.; Kim, S.G.
Plant Mol. Biol.
63
465-477
Pyrimidine-specific ribonucleoside hydrolase from the archaeon Sulfolobus solfataricus - biochemical characterization and homology modeling
2008
Porcelli, M.; Concilio, L.; Peluso, I.; Marabotti, A.; Facchiano, A.; Cacciapuoti, G.
FEBS J.
275
1900-1914
Characterization of a Giardia lamblia WB C6 clone resistant to the isoflavone formononetin
2007
Sterk, M.; Mueller, J.; Hemphill, A.; Mueller, N.
Microbiology
153
4150-4158
Isolation, crystallization and preliminary crystallographic analysis of Salmonella typhimurium uridine phosphorylase crystallized with 2,2-anhydrouridine
2007
Timofeev, V.I.; Lashkov, A.A.; Gabdoulkhakov, A.G.; Pavlyuk, B.P.; Kachalova, G.S.; Betzel, C.; Morgunova, E.Y.; Zhukhlistova, N.E.; Mikhailov, A.M.
Acta Crystallogr. Sect. F
63
852-854
Up-regulated expression of the uridine phosphorylase gene in human gastric tumors is correlated with a favorable prognosis
2007
Kawamura, K.; Takiguchi, N.; Wada, A.; Takenobu, H.; Kimura, H.; Soda, H.; Nagata, M.; Asano, T.; Tagawa, M.
Anticancer Res.
26
4647-4651
Kinetic parameters and recognition of thymidine analogues with varying functional groups by thymidine phosphorylase
2008
Hatano, A.; Harano, A.; Takigawa, Y.; Naramoto, Y.; Toda, K.; Nakagomi, Y.; Yamada, H.
Bioorg. Med. Chem.
16
3866-3870
Uridine protects cortical neurons from glucose deprivation-induced death: possible role of uridine phosphorylase
2008
Choi, J.W.; Shin, C.Y.; Choi, M.S.; Yoon, S.Y.; Ryu, J.H.; Lee, J.C.; Kim, W.K.; El Kouni, M.H.; Ko, K.H.
J. Neurotrauma
25
695-707
Pyrimidine acyclic nucleoside phosphonates and phosphorylated analogs. Part 2. Syntheses and investigation of their inhibitory effects towards human thymidine phosphorylase
2008
Pomeisl, K.; Holy, A.; Votruba, I.
Nucleic Acids Symp. Ser.
52
657-658
Modulation of human cytidine deaminase by specific amino acids involved in the intersubunit interactions
2007
Vincenzetti, S.; Quadrini, B.; Mariani, P.; De Sanctis, G.; Cammertoni, N.; Polzonetti, V.; Pucciarelli, S.; Natalini, P.; Vita, A.
Proteins
70
144-156
Tissue levels of pyrimidine nucleoside phosphorylase activity in human and rodent bladder cancer and normal bladder tissue
2007
Fujimoto, K.; Matsumura, Y.; Tani, Y.; Ozono, S.; Hirao, Y.; Okajima, E.
Int. J. Urol.
14
754-759
Human uridine-cytidine kinase phosphorylation of ribavirin: a convenient method for activation of ribavirin for conjugation to proteins
2008
Jukic, L.V.; Duvnjak, M.; Wu, C.H.; Wu, G.Y.
J. Biomed. Sci.
15
205-213
Structural basis for substrate specificity in group I nucleoside hydrolases
2008
Iovane, E.; Giabbai, B.; Muzzolini, L.; Matafora, V.; Fornili, A.; Minici, C.; Giannese, F.; Degano, M.
Biochemistry
47
4418-4426
A novel nucleoside kinase from Burkholderia thailandensis: a member of the phosphofructokinase B-type family of enzymes
2008
Ota, H.; Sakasegawa, S.; Yasuda, Y.; Imamura, S.; Tamura, T.
FEBS J.
275
5865-5872
Nicotinamide riboside and nicotinic acid riboside salvage in fungi and mammals. Quantitative basis for Urh1 and purine nucleoside phosphorylase function in NAD+ metabolism
2009
Belenky, P.; Christensen, K.C.; Gazzaniga, F.; Pletnev, A.A.; Brenner, C.
J. Biol. Chem.
284
158-164
Uridine-ribohydrolase is a key regulator in the uridine degradation pathway of Arabidopsis
2009
Jung, B.; Floerchinger, M.; Kunz, H.H.; Traub, M.; Wartenberg, R.; Jeblick, W.; Neuhaus, H.E.; Moehlmann, T.
Plant Cell
21
876-891
Crystallization and preliminary X-ray c uridine phosphorylase complexed with 5-fluorouracil
2009
Lashkov, A.A.; Gabdoulkhakov, A.G.; Shtil, A.A.; Mikhailov, A.M.
Acta Crystallogr. Sect. F
65
601-603
The kinetic mechanism of human uridine phosphorylase 1: Towards the development of enzyme inhibitors for cancer chemotherapy
2010
Renck, D.; Ducati, R.G.; Palma, M.S.; Santos, D.S.; Basso, L.A.
Arch. Biochem. Biophys.
497
35-42
Inhibition of CTP synthase from Escherichia coli by xanthines and uric acids
2010
Roy, A.C.; Lunn, F.A.; Bearne, S.L.
Bioorg. Med. Chem. Lett.
20
141-144
Implications of the structure of human uridine phosphorylase 1 on the development of novel inhibitors for improving the therapeutic window of fluoropyrimidine chemotherapy
2009
Roosild, T.P.; Castronovo, S.; Fabbiani, M.; Pizzorno, G.
BMC Struct. Biol.
9
14
-
Syntheses of 5-chlorouracils/thymines with 1-[phosphono(methyl/difluoromethyl)]-1,2-unsaturated-moiety-substituted methyl groups at N(1) and human thymidine phosphorylase inhibitory activity
2009
Birck, M.; Clinch, K.; Gainsford, G.; Schramm, V.; Tyler, P.
Helv. Chim. Acta
92
823-838
The crystal structure and activity of a putative trypanosomal nucleoside phosphorylase reveal it to be a homodimeric uridine phosphorylase
2010
Larson, E.T.; Mudeppa, D.G.; Gillespie, J.R.; Mueller, N.; Napuli, A.J.; Arif, J.A.; Ross, J.; Arakaki, T.L.; Lauricella, A.; Detitta, G.; Luft, J.; Zucker, F.; Verlinde, C.L.; Fan, E.; Van Voorhis, W.C.; Buckner, F.S.; Rathod, P.K.; Hol, W.G.; Merritt, E.A.
J. Mol. Biol.
396
1244-1259
Peroxisome proliferator-activated receptor gamma coactivator-1alpha enhances antiproliferative activity of 5-deoxy-5-fluorouridine in cancer cells through induction of uridine phosphorylase
2009
Kong, X.; Fan, H.; Liu, X.; Wang, R.; Liang, J.; Gupta, N.; Chen, Y.; Fang, F.; Chang, Y.
Mol. Pharmacol.
76
854-860
Quantum mechanics/molecular mechanics investigation of the mechanism of phosphate transfer in human uridine-cytidine kinase 2
2009
Smith, A.J.; Li, Y.; Houk, K.N.
Org. Biomol. Chem.
7
2716-2724
Thymidine kinase and uridine-cytidine kinase from Entamoeba histolytica: cloning, characterization, and search for specific inhibitors
2009
Lossani, A.; Torti, A.; Gatti, S.; Bruno, A.; Maserati, R.; Wright, G.E.; Focher, F.
Parasitology
136
595-602
Uridine ribohydrolase and the balance between nucleotide degradation and salvage
2009
Mach, J.
Plant Cell
21
699
Structure and mechanism of the 6-oxopurine nucleosidase from Trypanosoma brucei brucei
2010
Vandemeulebroucke, A.; Minici, C.; Bruno, I.; Muzzolini, L.; Tornaghi, P.; Parkin, D.W.; Versees, W.; Steyaert, J.; Degano, M.
Biochemistry
49
8999-9010
Arabidopsis thaliana nucleosidase mutants provide new insights into nucleoside degradation
2011
Riegler, H.; Geserick, C.; Zrenner, R.
New Phytol.
191
349-359
Arabidopsis nucleoside hydrolases involved in intracellular and extracellular degradation of purines
2011
Jung, B.; Hoffmann, C.; Moehlmann, T.
Plant J.
65
703-711
Nicotinamide riboside kinase structures reveal new pathways to NAD+
2007
Tempel, W.; Rabeh, W.M.; Bogan, K.L.; Belenky, P.; Wojcik, M.; Seidle, H.F.; Nedyalkova, L.; Yang, T.; Sauve, A.A.; Park, H.W.; Brenner, C.
PLoS Biol.
5
e263
Characterization of pyrimidine nucleoside phosphorylase of Mycoplasma hyorhinis: implications for the clinical efficacy of nucleoside analogues
2012
Vande Voorde, J.; Gago, F.; Vrancken, K.; Liekens, S.; Balzarini, J.
Biochem. J.
445
113-123
Inhibition of pyrimidine and purine nucleoside phosphorylases by a 3,5-dichlorobenzoyl-substituted 2-deoxy-D-ribose-1-phosphate derivative
2012
Vande Voorde, J.; Quintiliani, M.; McGuigan, C.; Liekens, S.; Balzarini, J.
Biochem. Pharmacol.
83
1358-1363
2',5'-Oligoadenylates and related 2',5'-oligonucleotide analogues. 1. Substrate specificity of the interferon-induced murine 2',5'-oligoadenylate synthetase and enzymatic synthesis of oligomers
1983
Hughes, B.; Srivastava, P.; Muse, D.; Robins, R.
Biochemistry
22
2116-2126
A single amino acid limits the substrate specificity of Thermus thermophilus uridine-cytidine kinase to cytidine
2011
Tomoike, F.; Nakagawa, N.; Kuramitsu, S.; Masui, R.
Biochemistry
50
4597-4607
The crystal structure of Streptococcus pyogenes uridine phosphorylase reveals a distinct subfamily of nucleoside phosphorylases
2011
Tran, T.H.; Christoffersen, S.; Allan, P.W.; Parker, W.B.; Piskur, J.; Serra, I.; Terreni, M.; Ealick, S.E.
Biochemistry
50
6549-6558
Uridine phosphorylase from Trypanosoma cruzi: kinetic and chemical mechanisms
2011
Silva, R.G.; Schramm, V.L.
Biochemistry
50
9158-9166
Exploring new inhibitors of Plasmodium falciparum purine nucleoside phosphorylase
2010
Cui, H.; Ruda, G.F.; Carrero-Lerida, J.; Ruiz-Perez, L.M.; Gilbert, I.H.; Gonzalez-Pacanowska, D.
Eur. J. Med. Chem.
45
5140-5149
The structural and molecular biology of type I galactosemia: enzymology of galactose 1-phosphate uridylyltransferase
2011
McCorvie, T.J.; Timson, D.J.
IUBMB Life
63
694-700
Trypanosoma brucei thymidine kinase is tandem protein consisting of two homologous parts, which together enable efficient substrate binding
2012
Ranjbarian, F.; Vodnala, M.; Vodnala, S.M.; Rofougaran, R.; Thelander, L.; Hofer, A.
J. Biol. Chem.
287
17628-17636
Structural and mechanistic characterization of leukocyte-type core 2 ?1,6-N-acetylglucosaminyltransferase: a metal-ion-independent GT-A glycosyltransferase
2011
Pak, J.E.; Satkunarajah, M.; Seetharaman, J.; Rini, J.M.
J. Mol. Biol.
414
798-811
-
Comparative investigations on thermostable pyrimidine nucleoside phosphorylases from Geobacillus thermoglucosidasius and Thermus thermophilus
2012
Szeker, K.; Zhou, X.; Schwab, T.; Casanueva, A.; Cowan, D.; Mikhailopulo, I.; Neubauer, P.
J. Mol. Catal. B
84
27-34
A high-throughput screen for directed evolution of the natural product sulfotransferase LipB
2011
Koryakina, I.; Neville, J.; Nonaka, K.; van Lanen, S.G.; Williams, G.J.
J. Biomol. Screen.
16
845-851
Biosynthesis of nucleoside analogues via thermostable nucleoside phosphorylase
2013
Zhu, S.; Song, D.; Gong, C.; Tang, P.; Li, X.; Wang, J.; Zheng, G.
Appl. Microbiol. Biotechnol.
97
6769-6778
Characterization of inosine-uridine nucleoside hydrolase (RihC) from Escherichia coli
2014
Arivett, B.; Farone, M.; Masiragani, R.; Burden, A.; Judge, S.; Osinloye, A.; Minici, C.; Degano, M.; Robinson, M.; Kline, P.
Biochim. Biophys. Acta
1844
656-662
Structure and function of nucleoside hydrolases from Physcomitrella patens and maize catalyzing the hydrolysis of purine, pyrimidine, and cytokinin ribosides
2013
Kopecna, M.; Blaschke, H.; Kopecny, D.; Vigouroux, A.; Koncitikova, R.; Novak, O.; Kotland, O.; Strnad, M.; Morera, S.; von Schwartzenberg, K.
Plant Physiol.
163
1568-1583
A pentose bisphosphate pathway for nucleoside degradation in Archaea
2015
Aono, R.; Sato, T.; Imanaka, T.; Atomi, H.
Nat. Chem. Biol.
11
355-360
High-syn conformation of uridine and asymmetry of the hexameric molecule revealed in the high-resolution structures of Shewanella oneidensis MR-1 uridine phosphorylase in the free form and in complex with uridine
2014
Safonova, T.N.; Mikhailov, S.N.; Veiko, V.P.; Mordkovich, N.N.; Manuvera, V.A.; Alekseev, C.S.; Kovalchuk, M.V.; Popov, V.O.; Polyakov, K.M.
Acta Crystallogr. Sect. D
70
3310-3319
Concerted action of two subunits of the functional dimer of Shewanella oneidensis MR-1 uridine phosphorylase derived from a comparison of the C212S mutant and the wild-type enzyme
2016
Safonova, T.N.; Mordkovich, N.N.; Veiko, V.P.; Okorokova, N.A.; Manuvera, V.A.; Dorovatovskii, P.V.; Popov, V.O.; Polyakov, K.M.
Acta Crystallogr. Sect. D
72
203-210
Crystallization and preliminary X-ray study of Vibrio cholerae uridine phosphorylase in complex with 6-methyluracil
2014
Prokofev, I.I.; Lashkov, A.A.; Gabdulkhakov, A.G.; Dontsova, M.V.; Seregina, T.A.; Mironov, A.S.; Betzel, C.; Mikhailov, A.M.
Acta Crystallogr. Sect. F
70
60-63
Analysis of two Schistosoma mansoni uridine phosphorylases isoforms suggests the emergence of a protein with a non-canonical function
2016
da Silva Neto, A.M.; Torini de Souza, J.R.; Romanello, L.; Cassago, A.; Serrao, V.H.; DeMarco, R.; Brandao-Neto, J.; Garratt, R.C.; Pereira, H.D.
Biochimie
125
12-22
-
In silico analysis of the three-dimensional structures of the homodimer of uridine phosphorylase from Yersinia pseudotuberculosis in the ligand-free state and in a complex with 5-fluorouracil
2013
Lashkov, A.; Sotnichenko, S.; Mikhailov, A.
Crystallogr. Rep.
58
280-286
-
Three-dimensional structures of unligated uridine phosphorylase from Yersinia pseudotuberculosis at 1.4 Ã
resolution and its complex with an antibacterial drug
2015
Balaev, V.; Lashkov, A.; Gabdulkhakov, A.; Dontsova, M.; Mironov, A.; Betzel, C.; Mikhailov, A.
Crystallogr. Rep.
60
525-531
Physicochemical characterization of uridine phosphorylase from Shewanella oneidensis MR-1
2013
Mordkovich, N.; Safonova, T.; Manuvera, V.; Veiko, V.; Polyakov, K.; Alekseev, K.; Mikhailov, S.; Popov, V.
Dokl. Biochem. Biophys.
451
187-189
Human uridine phosphorylase-1 inhibitors: a new approach to ameliorate 5-fluorouracil-induced intestinal mucositis
2014
Renck, D.; Santos, A.A.; Machado, P.; Petersen, G.O.; Lopes, T.G.; Santos, D.S.; Campos, M.M.; Basso, L.A.
Invest. New Drugs
32
1301-1307
Enzymatic synthesis of 2-deoxyuridine by whole cell catalyst co-expressing uridine phosphorylase and thymidine phosphorylase through auto-induction system
2014
Xiong, S.; Wang, Y.; Wang, X.; Wang, J.; Li, J.; Zhang, G.; Zhang, R.; Xie, L.; Wang, H.
J. Biosci. Bioeng.
118
723-727
Design of novel potent inhibitors of human uridine phosphorylase-1: synthesis, inhibition studies, thermodynamics, and in vitro influence on 5-fluorouracil cytotoxicity
2013
Renck, D.; Machado, P.; Souto, A.A.; Rosado, L.A.; Erig, T.; Campos, M.M.; Farias, C.B.; Roesler, R.; Timmers, L.F.; de Souza, O.N.; Santos, D.S.; Basso, L.A.
J. Med. Chem.
56
8892-8902
-
A comparison between immobilized pyrimidine nucleoside phosphorylase from Bacillus subtilis and thymidine phosphorylase from Escherichia coli in the synthesis of 5-substituted pyrimidine 2'-deoxyribonucleosides
2013
Serra, I.; Bavaro, T.; Cecchini, D.; Daly, S.; Albertini, A.; Terreni, M.; Ubiali, D.
J. Mol. Catal. B
95
16-22
The pyrimidine nucleoside phosphorylase of Mycoplasma hyorhinis and how it may affect nucleoside-based therapy
2014
Vande Voorde, J.; Liekens, S.; Gago, F.; Balzarini, J.
Nucleosides Nucleotides Nucleic Acids
33
394-402
Gene amplification and point mutations in pyrimidine metabolic genes in 5-fluorouracil resistant Leishmania infantum
2013
Ritt, J.; Raymond, F.; Leprohon, P.; Légaré, D.; Corbeil, J.; Ouellette, M.
PLoS Negl. Trop. Dis.
7
e2564
-
Immobilized Drosophila melanogaster deoxyribonucleoside kinase (DmdNK) as a high performing biocatalyst for the synthesis of purine arabinonucleotides
2014
Serra, I.; Conti, S.; PiÃ
¡kur, J.; Clausen, A.; Munch-Petersen, B.; Terreni, M.; Ubiali, D.
Adv. Synth. Catal.
356
563-570
The pivotal role of uridine-cytidine kinases in pyrimidine metabolism and activation of cytotoxic nucleoside analogues in neuroblastoma
2016
van Kuilenburg, A.B.; Meinsma, R.
Biochim. Biophys. Acta
1862
1504-1512
Phosphorylation of uridine and cytidine by uridine-cytidine kinase
2014
Qian, Y.; Ding, Q.; Li, Y.; Zou, Z.; Yan, B.; Ou, L.
J. Biotechnol.
188
81-87
Nucleoside kinases in adult Schistosoma mansoni: phosphorylation of pyrimidine nucleosides
2014
Naguib, F.N.; El Kouni, M.H.
Mol. Biochem. Parasitol.
194
53-55
In silico discovery of potential uridine-cytidine kinase 2 inhibitors from the rhizome of Alpinia mutica
2016
Malami, I.; Abdul, A.B.; Abdullah, R.; Bt Kassim, N.K.; Waziri, P.; Christopher Etti, I.
Molecules
21
417
Structural and kinetic characterization of thymidine kinase from Leishmania major
2015
Timm, J.; Bosch-Navarrete, C.; Recio, E.; Nettleship, J.E.; Rada, H.; Gonzalez-Pacanowska, D.; Wilson, K.S.
PLoS Negl. Trop. Dis.
9
e0003781
Structural and biochemical studies on the reaction mechanism of uridine-cytidine kinase
2015
Tomoike, F.; Nakagawa, N.; Kuramitsu, S.; Masui, R.
Protein J.
34
411-420
Purification of a non-specific nucleoside hydrolase from Alaska pea seeds
2019
Thicklin, L.; Shamsuddin, A.; Alahmry, F.; Gezley, C.; Brown, E.; Stone, J.; Burns-Carver, E.; Kline, P.C.
Protein Expr. Purif.
154
140-146
-
Thermodynamics, functional and structural characterization of inosine-uridine nucleoside hydrolase from Leishmania braziliensis
2017
Dalberto, P.; Martinelli, L.; Bachega, J.; Timmers, L.; Pinto, A.; Dadda, A.; Petersen, G.; Subtil, F.; Galina, L.; Villela, A.; Pissinate, K.; Machado, P.; Bizarro, C.; De Souza, O.; De Carvalho Filho, E.; Basso, L.; Santos, D.
RSC Adv.
7
48861-48875
Role of the uridine/cytidine kinase 2 mutation in cellular sensitiveness toward 3-ethynylcytidine treatment of human cancer cells
2017
Sato, A.; Takano, T.; Hiramoto, A.; Naito, T.; Matsuda, A.; Fukushima, M.; Wataya, Y.; Kim, H.S.
Anticancer Drugs
28
781-786
-
Study of structural-functional organization of nucleoside phosphorylases of gammaproteobacteria. Special aspects of functioning of uridine phosphorylase phosphate-binding site
2018
Mordkovich, N.; Safonova, T.; Antipov, A.; Manuvera, V.; Polyakov, K.; Okorokova, N.; Veiko, V.
Appl. Biochem. Microbiol.
54
12-20
Indispensable residue for uridine binding in the uridine-cytidine kinase family
2017
Tomoike, F.; Nakagawa, N.; Fukui, K.; Yano, T.; Kuramitsu, S.; Masui, R.
Biochem. Biophys. Rep.
11
93-98
Thermophilic nucleoside phosphorylases their properties, characteristics and applications
2020
Kamel, S.; Thiele, I.; Neubauer, P.; Wagner, A.
Biochim. Biophys. Acta
1868
140304
Involvement of the uridine cytidine kinase 2 enzyme in cancer cell death a molecular crosstalk between the enzyme and cellular apoptosis induction
2019
Malami, I.; Abdul, A.B.
Biomed. Pharmacother.
109
1506-1510
Discovery of small molecule inhibitors of human uridine-cytidine kinase 2 by high-throughput screening
2019
Okesli-Armlovich, A.; Gupta, A.; Jimenez, M.; Auld, D.; Liu, Q.; Bassik, M.C.; Khosla, C.
Bioorg. Med. Chem. Lett.
29
2559-2564
Molecular mechanisms of substrate specificities of uridine-cytidine kinase
2016
Tanaka, W.; Shoji, M.; Tomoike, F.; Ujiie, Y.; Hanaoka, K.; Harada, R.; Kayanuma, M.; Kamiya, K.; Ishida, T.; Masui, R.; Kuramitsu, S.; Shigeta, Y.
Biophys. Physicobiol.
13
77-84
A thermostable pyrimidine nucleoside phosphorylase from Brevibacillus borstelensis LK01 for synthesizing halogenated nucleosides
2017
Liu, K.; Zhou, Y.; Zhang, J.; Chu, J.; Zhang, Y.; He, B.
Biotechnol. Lett.
39
1903-1910
-
Structural and functional analysis of pyrimidine nucleoside phosphorylases of the NP-I and NP-II families in complexes with 6-methyluracil
2018
Prokofev, I.; Lashkov, A.; Gabdulkhakov, A.; Balaev, V.; Mironov, A.; Betzel, C.; Mikhailov, A.
Crystallogr. Rep.
63
418-427
-
X-ray structure and molecular dynamics study of uridine phosphorylase from Vibrio cholerae in complex with 2,2-anhydrouridine
2020
Eistrikh-Heller, P.; Rubinsky, S.; Prokofev, I.; Gabdulkhakov, A.; Mironov, A.; Lashkov, A.
Crystallogr. Rep.
65
269-277
-
Discovery of two diacetylene glycosides as human uridine-cytidine kinase 2 inhibitors An in silico approach
2016
Mohamed, M.; Dirar, A.; Hamdoun, S.
J. Appl. Pharm. Sci.
6
034-039
Overexpression of uridine-cytidine kinase 2 correlates with breast cancer progression and poor prognosis
2017
Shen, G.; He, P.; Mao, Y.; Li, P.; Luh, F.; Ding, G.; Liu, X.; Yen, Y.
J. Breast Cancer
20
132-141
Uridine phosphorylase 1 associates to biological and clinical significance in thyroid carcinoma cell lines
2019
Guan, Y.; Bhandari, A.; Zhang, X.; Wang, O.
J. Cell. Mol. Med.
23
7438-7448
Purification, activity, and expression levels of two uridine-cytidine kinase isoforms in neuroblastoma cell lines
2016
Meinsma, R.; van Kuilenburg, A.B.
Nucleosides Nucleotides Nucleic Acids
35
613-618
Substrate specificity of E. coli uridine phosphorylase. Further evidences of high-syn conformation of the substrate in uridine phosphorolysis
2017
Alexeev, C.S.; Sivets, G.G.; Safonova, T.N.; Mikhailov, S.N.
Nucleosides Nucleotides Nucleic Acids
36
107-121
The cytidine analog fluorocyclopentenylcytosine (RX-3117) is activated by uridine-cytidine kinase 2
2016
Sarkisjan, D.; Julsing, J.R.; Smid, K.; de Klerk, D.; van Kuilenburg, A.B.; Meinsma, R.; Lee, Y.B.; Kim, D.J.; Peters, G.J.
PLoS ONE
11
e0162901
Distinct substrate specificity and physicochemical characterization of native human hepatic thymidine phosphorylase
2018
Oh, T.; El Kouni, M.H.
PLoS ONE
13
e0202826
-
Dynamic modelling of phosphorolytic cleavage catalyzed by pyrimidine-nucleoside phosphorylase
2019
Giessmann, R.; Krausch, N.; Kaspar, F.; Bournazou, M.; Wagner, A.; Neubauer, P.; Gimpel, M.
Processes
7
380
Structural and catalytic analysis of two diverse uridine phosphorylases in Phytophthora capsici
2020
Yang, C.; Li, J.; Huang, Z.; Zhang, X.; Gao, X.; Zhu, C.; Morris, P.F.; Zhang, X.
Sci. Rep.
10
9051
Molecular cloning and expression of the pyrimidine nucleoside phosphorylase gene from Bacillus stearothermophilus TH 6-2
1996
Okuyama, K.; Hamamoto, T.; Noguchi, T.; Midorikawa, Y.
Biosci. Biotechnol. Biochem.
60
1655-1659
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