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BRENDA support

Ligand benzyl alcohol

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Basic Ligand Information

Molecular Structure
Picture of benzyl alcohol (click for magnification)
Molecular Formula
BRENDA Name
InChIKey
C7H8O
benzyl alcohol
WVDDGKGOMKODPV-UHFFFAOYSA-N
Synonyms:
1-phenylmethanol, aromatic alcohol, aromatic primary alcohol, benzylalcohol, benzyl alkohol, benzylalkohol, phenylmethanol
Pathway Source
Pathways
BRENDA
aerobic toluene degradation
KEGG
Degradation of aromatic compounds, Microbial metabolism in diverse environments, Toluene degradation
MetaCyc
benzoate biosynthesis I (CoA-dependent, beta-oxidative), salicin biosynthesis, salicortin biosynthesis, tea aroma glycosidic precursor bioactivation, toluene degradation to benzoate more


Show all pahtways known for Show all BRENDA pathways known for benzyl alcohol

Roles as Enzyme Ligand

In Vivo Substrate in Enzyme-catalyzed Reactions (6 results)

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EC NUMBER
PROVEN IN VIVO REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
benzyl alcohol + NADP+ = benzaldehyde + NADPH
show the reaction diagram
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benzyl alcohol + O2 = benzaldehyde + H2O2
show the reaction diagram
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benzoyl-CoA + benzyl alcohol = benzyl benzoate + CoA
show the reaction diagram
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acetyl-CoA + benzyl alcohol = CoA + benzyl acetate
show the reaction diagram
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In Vivo Product in Enzyme-catalyzed Reactions (7 results)

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EC NUMBER
PROVEN IN VIVO REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
benzaldehyde + NADPH + H+ = benzylalcohol + NADP+
show the reaction diagram
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benzaldehyde + NAD(P)H + H+ = benzyl alcohol + NAD(P)+
show the reaction diagram
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benzyl 6-O-(beta-D-xylopyranosyl)-beta-D-glucopyranoside + H2O = benzyl alcohol + 6-O-(beta-D-xylopyranosyl)-beta-D-glucopyranose
show the reaction diagram
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2-oxopentanedioic acid 5-benzyl ester + H2O = 2-oxoglutarate + benzyl alcohol
show the reaction diagram
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Substrate in Enzyme-catalyzed Reactions (65 results)

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EC NUMBER
REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
benzylalcohol + NADP+ = benzaldehyde + NADPH
show the reaction diagram
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benzyl alcohol + oxidized 3-acetylpyridine adenine dinucleotide + H+ = benzaldehyde + reduced 3-acetylpyridine adenine dinucleotide
show the reaction diagram
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benzyl alcohol + NADP+ = ?
show the reaction diagram
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benzyl alcohol + NAD+ = benzaldehyde + NADH + H+
show the reaction diagram
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benzylalcohol + NAD+ = benzaldehyde + NADH
show the reaction diagram
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benzyl alcohol + NADP+ = benzaldehyde + NADPH
show the reaction diagram
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benzyl alcohol + ferricytochrome c = benzaldehyde + ferrocytochrome c + H+
show the reaction diagram
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benzyl alcohol + O2 = benzaldehyde + H2O2
show the reaction diagram
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benzyl alcohol + O2 = benzaldehyde + H2O2
show the reaction diagram
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benzyl alcohol + O2 = benzaldehyde + H2O2
show the reaction diagram
-
benzyl alcohol + O2 = benzaldehyde + H2O2
show the reaction diagram
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benzyl alcohol + 2,6-dichlorophenolindophenol = benzaldehyde + reduced 2,6-dichlorophenolindophenol
show the reaction diagram
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benzyl alcohol + N,N,N',N'-tetramethyl-p-phenylenediamine = benzaldehyde + ?
show the reaction diagram
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benzyl alcohol + H2O2 = benzaldehyde + H2O
show the reaction diagram
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benzyl alcohol + NAD+ = benzaldehyde + NADH
show the reaction diagram
-
benzyl alcohol + NAD+ + H2O = ? + NADH
show the reaction diagram
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acetyl-CoA + benzyl alcohol = CoA + benzyl acetate
show the reaction diagram
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acetyl-CoA + benzyl alcohol = CoA + benzyl acetate
show the reaction diagram
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UDP-glucose + benzyl alcohol = UDP + benzyl-beta-D-glucoside
show the reaction diagram
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UDPglucose + benzyl alcohol = UDP + benzyl beta-D-glucoside
show the reaction diagram
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3'-phosphoadenylylsulfate + benzyl alcohol = adenosine 3',5'-bisphosphate + benzyl sulfate
show the reaction diagram
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3'-phosphoadenylylsulfate + benzyl alcohol = adenosine 3',5'-bisphosphate + benzyl sulfate
show the reaction diagram
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4-nitrophenyl sulfate + benzyl alcohol = 4-nitrophenol + benzyl sulfate
show the reaction diagram
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Product in Enzyme-catalyzed Reactions (160 results)

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EC NUMBER
REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
benzaldehyde + NADPH = benzyl alcohol + NADP+
show the reaction diagram
-
benzaldehyde + NADPH + H+ = benzyl alcohol + NADP+
show the reaction diagram
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benzaldehyde + NADPH = benzyl alcohol + NADP+
show the reaction diagram
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benzaldehyde + NADPH + H+ = benzyl alcohol + NADP+
show the reaction diagram
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benzaldehyde + NADPH = benzyl alcohol + NADP+
show the reaction diagram
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benzaldehyde + NADPH = benzyl alcohol + NADP+
show the reaction diagram
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benzaldehyde + NADH + H+ = benzyl alcohol + NAD+
show the reaction diagram
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toluene + O2 + 2 reduced ferredoxin [iron-sulfur] cluster + 2 H+ = benzyl alcohol + 2 oxidized ferredoxin [iron-sulfur] cluster + H2O
show the reaction diagram
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benzoic acid + NADPH + H+ + ATP = benzaldehyde + benzyl alcohol + NADP+ + AMP + diphosphate
show the reaction diagram
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benzaldehyde + NADH + H+ = benzyl alcohol + NAD+
show the reaction diagram
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benzyl acetate + H2O = benzyl alcohol + acetate
show the reaction diagram
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benzyl propionate + H2O = benzyl alcohol + propionate
show the reaction diagram
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n-butyl benzyl phthalate + H2O = 1,3-isobenzofurandione + n-butanol + benzyl alcohol
show the reaction diagram
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L-Leu-benzyl ester + H2O = L-Leu + benzylalcohol
show the reaction diagram
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N-benzoyl-Arg benzyl ester + H2O = N-benzoyl-Arg + benzyl alcohol
show the reaction diagram
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2-oxopentanedioic acid 5-benzyl ester + H2O = 2-oxoglutarate + benzyl alcohol
show the reaction diagram
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Inhibitor in Enzyme-catalyzed Reactions (14 results)

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EC NUMBER
COMMENTARY
LITERATURE
ENZYME 3D STRUCTURE
competitive mechanism, substrate inhibition
-
0.5 mM, 10% inhibition
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100 mM, 52% inhibition, reversible, may be due to changes in membrane fluidity
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complete inhibition at 1% (v/v)
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slight inhibition
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Ki: 2.6 mM
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3D Structure of Enzyme-Ligand-Complex (PDB) (27 results)

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Enzyme Kinetic Parameters

kcat Value (Turnover Number) (80 results)

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EC NUMBER
TURNOVER NUMBER [1/S]
TURNOVER NUMBER MAXIMUM [1/S]
COMMENTARY
LITERATURE
8.4
-
pH 7.5, 37°C, recombinant enzyme
0.0733
-
-
93.3
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at pH 6.5 and 65°C
0.013
-
isoform SULT1A1, at pH 7.0 and 37°C

KM Value (148 results)

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EC NUMBER
KM VALUE [MM]
KM VALUE MAXIMUM [MM]
COMMENTARY
LITERATURE
0.007
-
-
76
-
pH and temperature not specified in the publication
26.6
-
-
0.001
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pH 7.0, 20°C
5.5
-
-
0.3
-
-

Ki Value (5 results)

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EC NUMBER
KI VALUE [MM]
KI VALUE MAXIMUM [MM]
COMMENTARY
LITERATURE
10
-
-
9.28
-
at 25°C, pH not specified in the publication
1.4
-
-
2.6
-
-
0.01529
-
-

References & Links

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Links to other databases for benzyl alcohol

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ChEBI
PubChem
ChEBI
PubChem