Ligand N-acetyl-alpha-D-glucosamine 1-phosphate

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Basic Ligand Information

Molecular Structure
Picture of N-acetyl-alpha-D-glucosamine 1-phosphate (click for magnification)
Molecular Formula
BRENDA Name
InChIKey
C8H16NO9P
N-acetyl-alpha-D-glucosamine 1-phosphate
FZLJPEPAYPUMMR-FMDGEEDCSA-N
Synonyms:
2-(acetylamino)-2-deoxy-1-O-phosphono-alpha-D-glucopyranose, 2-amino-2-deoxy-alpha-D-glucopyranosyl 1-phosphate, N-acetyl-alpha-D-glucosaminyl-1-phosphate, N-acetyl-D-glucosamine-1-phosphate, N-acetyl-D-glucosamine 1-phosphate, N-acetyl-D-glucosamine phosphate, N-acetylglucosamine-1-phosphate, N-acetylglucosamine-phosphate, N-acetylglucosamine 1-phosphate, N-acetylglucosaminyl phosphate


Show all pahtways known for Show all BRENDA pathways known for N-acetyl-alpha-D-glucosamine 1-phosphate

Roles as Enzyme Ligand

In Vivo Substrate in Enzyme-catalyzed Reactions (26 results)

EC NUMBER
PROVEN IN VIVO REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE

In Vivo Product in Enzyme-catalyzed Reactions (23 results)

EC NUMBER
PROVEN IN VIVO REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
N,N'-diacetylchitobiose + phosphate = N-acetyl-D-glucosamine + N-acetyl-alpha-D-glucosamine 1-phosphate
show the reaction diagram
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ATP + N-acetyl-D-glucosamine = ADP + N-acetyl-D-glucosamine 1-phosphate
show the reaction diagram
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UDP-N-acetyl-alpha-D-glucosamine + H2O = UMP + N-acetyl-alpha-D-glucosaminyl-1-phosphate
show the reaction diagram
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Substrate in Enzyme-catalyzed Reactions (67 results)

EC NUMBER
REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
maltotetraose + 2-amino-2-deoxy-alpha-D-glucopyranosyl 1-phosphate = GlcNAc-alpha-(1->4)-Glc-alpha-(1->4)-Glc-alpha-(1->4)-Glc-alpha-(1->4)-Glcalpha + phosphate
show the reaction diagram
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UDP-alpha-D-glucose + N-acetyl-alpha-D-glucosamine 1-phosphate = alpha-D-glucose 1-phosphate + UDP-N-acetyl-alpha-D-glucosamine
show the reaction diagram
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dTTP + N-acetyl-alpha-D-glucosamine 1-phosphate = diphosphate + dTDP-N-acetyl-alpha-D-glucosamine
show the reaction diagram
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N-acetylglucosamine 1-phosphate + H2O = N-acetylglucosamine + phosphate
show the reaction diagram
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N-acetyl-alpha-D-glucosamine 1-phosphate = N-acetyl-D-glucosamine + phosphate
show the reaction diagram
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N-Acetyl-D-glucosamine 1-phosphate = ?
show the reaction diagram
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N-acetyl-D-glucosamine-1-phosphate = N-acetyl-D-glucosamine-6-phosphate
show the reaction diagram
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N-acetyl-D-glucosamine-1-phosphate = N-acetyl-D-glucosamine-6-phosphate
show the reaction diagram
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Product in Enzyme-catalyzed Reactions (58 results)

EC NUMBER
REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
phosphohistidinoprotein + N-acetyl-D-glucosamine = histidine-containing protein + N-acetyl-D-glucosamine phosphate
show the reaction diagram
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ATP + N-acetyl-alpha-D-glucosamine = ADP + N-acetyl-alpha-D-glucosamine 1-phosphate
show the reaction diagram
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ATP + N-acetyl-D-glucosamine = ADP + N-acetyl-D-glucosamine 1-phosphate
show the reaction diagram
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UDP-acetylglucosamine + phosphate = UDP + N-acetyl-alpha-D-glucosamine 1-phosphate
show the reaction diagram
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diphosphate + UDP-N-acetylglucosamine = UTP + N-acetylglucosamine 1-phosphate
show the reaction diagram
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UDP-N-acetyl-D-glucosamine = UMP + N-acetyl-D-glucosamine 1-phosphate
show the reaction diagram
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UDP-N-acetyl-alpha-D-glucosamine + H2O = UMP + N-acetyl-alpha-D-glucosaminyl-1-phosphate
show the reaction diagram
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Activator in Enzyme-catalyzed Reactions (1 result)

EC NUMBER
COMMENTARY
LITERATURE
ENZYME 3D STRUCTURE
activation at low UDP-N-acetylmannosamine concentrations
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Inhibitor in Enzyme-catalyzed Reactions (6 results)

EC NUMBER
COMMENTARY
LITERATURE
ENZYME 3D STRUCTURE

3D Structure of Enzyme-Ligand-Complex (PDB) (13 results)

Enzyme Kinetic Parameters

kcat Value (Turnover Number) (25 results)

EC NUMBER
TURNOVER NUMBER [1/S]
TURNOVER NUMBER MAXIMUM [1/S]
COMMENTARY
LITERATURE
12.4
-
GmlU uridyltransferase
0.2
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pH 8.0, 73°C

KM Value (38 results)

EC NUMBER
KM VALUE [MM]
KM VALUE MAXIMUM [MM]
COMMENTARY
LITERATURE
0.93
-
pH 7.0, 30°C, reverse phosphorolysis reaction
0.6
-
pH 8.0, 73°C

References & Links

Links to other databases for N-acetyl-alpha-D-glucosamine 1-phosphate

ChEBI
PubChem
ChEBI
PubChem