Ligand D-ornithine

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Basic Ligand Information

Molecular Structure
Picture of D-ornithine (click for magnification)
Molecular Formula
BRENDA Name
InChIKey
C5H12N2O2
D-ornithine
AHLPHDHHMVZTML-SCSAIBSYSA-N
Synonyms:
D-Orn


Show all pahtways known for Show all BRENDA pathways known for D-ornithine

Roles as Enzyme Ligand

In Vivo Substrate in Enzyme-catalyzed Reactions (5 results)

EC NUMBER
PROVEN IN VIVO REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
D-ornithine + H2O + O2 = 5-amino-2-oxopentanoate + NH3 + H2O2
show the reaction diagram
-
D-ornithine = putrescine + CO2
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-
ATP + D-ornithine + citrate = AMP + diphosphate + N5-[(S)-citryl]-D-ornithine
show the reaction diagram
-

In Vivo Product in Enzyme-catalyzed Reactions (1 result)

EC NUMBER
PROVEN IN VIVO REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
L-Ornithine = D-Ornithine
show the reaction diagram
-
-

Substrate in Enzyme-catalyzed Reactions (19 results)

EC NUMBER
REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
D-ornithine + H2O + iodonitrotetrazolium chloride = ? + NH3 + reduced iodonitrotetrazolium chloride
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D-ornithine + pyruvate + NADPH + H+ = N5-(L-1-carboxyethyl)-D-ornithine + NADP+ + H2O
show the reaction diagram
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D-ornithine = putrescine + CO2
show the reaction diagram
-
D-ornithine = putrescine + CO2
show the reaction diagram
-
D-ornithine = L-ornithine
show the reaction diagram
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D-ornithine = L-ornithine
show the reaction diagram
-
D-ornithine = L-ornithine
show the reaction diagram
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ATP + UDP-MurNAc-L-Ala-D-Glu + D-ornithine = ?
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ATP + D-ornithine + citrate = AMP + diphosphate + N5-[(S)-citryl]-D-ornithine
show the reaction diagram
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D-ornithine + ATP + H2O = ?
show the reaction diagram
-

Product in Enzyme-catalyzed Reactions (10 results)

EC NUMBER
REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
N-carbamoyl-D-ornithine + H2O = D-ornithine + CO2 + NH3
show the reaction diagram
-
-
D-arginine + H2O = D-ornithine + urea
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D-arginine + H2O = D-ornithine + urea
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D-arginine + H2O = D-ornithine + urea
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-
L-Ornithine = D-Ornithine
show the reaction diagram
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L-Ornithine = D-Ornithine
show the reaction diagram
-
-

Inhibitor in Enzyme-catalyzed Reactions (9 results)

EC NUMBER
COMMENTARY
LITERATURE
ENZYME 3D STRUCTURE
uncompetitive inhibition
-

Enzyme Kinetic Parameters

kcat Value (Turnover Number) (35 results)

EC NUMBER
TURNOVER NUMBER [1/S]
TURNOVER NUMBER MAXIMUM [1/S]
COMMENTARY
LITERATURE
6.2
-
-
0.42
-
pH 8.0, 37°C, recombinant wild-type enzyme
1.83
-
pH 8.0, 30°C, recombinant wild-type enzyme

KM Value (33 results)

EC NUMBER
KM VALUE [MM]
KM VALUE MAXIMUM [MM]
COMMENTARY
LITERATURE
1.48
-
-
4.2
-
pH 8.0, 37°C, recombinant wild-type enzyme
22
-
pH 8.0, 30°C, recombinant wild-type enzyme

Ki Value (2 results)

EC NUMBER
KI VALUE [MM]
KI VALUE MAXIMUM [MM]
COMMENTARY
LITERATURE
0.1
-
at pH 8.5 and 55°C
0.38
-
pH 7.8, 25°C

References & Links

Links to other databases for D-ornithine

ChEBI
PubChem
ChEBI
PubChem