Ligand quercetin O-glucuronide
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Basic Ligand Information
Molecular Structure

C21H18O13
quercetin O-glucuronide
DUBCCGAQYVUYEU-MBIBTLSJSA-N
quercetin-3-O-D-glucuronide, quercetin-3-O-glucuronide, quercetin 3-glucuronide, quercetin 3-O-glucuronate
Roles as Enzyme Ligand
Product in Enzyme-catalyzed Reactions (3 results)
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3 quercetin + 3 UDP-glucuronate = 3 UDP + quercetin 7-glucuronide + quercetin 3-glucuronide + quercetin 3'-glucuronide
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quercetin + UDPglucuronate = UDP + quercetin O-glucuronide
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quercetin + UDP-glucuronate = quercetin 3-O-glucuronate + UDP
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Inhibitor in Enzyme-catalyzed Reactions (2 results)
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uncompetitive inhibition
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better binding affinities than quercetin
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Enzyme Kinetic Parameters
Ki Value (1 result)
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References & Links
Literature References (3)
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The glucuronidation of exogenous and endogenous compounds by stably expressed rat and human UDP-glucuronosyltransferase 1.1
1996
King, C.D.; Green, M.D.; Rios, G.R.; Coffman, B.L.; Owens, I.S.; Bishop, W.P.; Tephly, T.R.
Arch. Biochem. Biophys.
332
92-100
Flavonols as potential antiviral drugs targeting SARS-CoV-2 proteases (3CLpro and PLpro), spike protein, RNA-dependent RNA polymerase (RdRp) and angiotensin-converting enzyme II receptor (ACE2)
2020
Mouffouk, C.; Mouffouk, S.; Mouffouk, S.; Hambaba, L.; Haba, H.
Eur. J. Pharmacol.
891
173759
Inhibition of the MurA enzyme in Fusobacterium nucleatum by potential inhibitors identified through computational and in vitro approaches
2017
Kumar, A.; Saranathan, R.; Prashanth, K.; Tiwary, B.K.; Krishna, R.
Mol. Biosyst.
13
939-954
Links to other databases for quercetin O-glucuronide