Ligand Gly-Phe

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Basic Ligand Information

Molecular Structure
Picture of Gly-Phe (click for magnification)
Molecular Formula
BRENDA Name
InChIKey
C11H14N2O3
Gly-Phe
JBCLFWXMTIKCCB-VIFPVBQESA-N
Synonyms:
GF, Gly-L-Phe, Gly-Phe-OH, glycine-L-phenylalanine

Roles as Enzyme Ligand

Substrate in Enzyme-catalyzed Reactions (4 results)

EC NUMBER
REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
Gly-Phe + H2O = Gly + Phe
show the reaction diagram
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Gly-Phe + H2O = Gly + Phe
show the reaction diagram
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Gly-Phe + H2O = Gly + Phe
show the reaction diagram
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Gly-Phe + H2O = Gly + Phe
show the reaction diagram
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Product in Enzyme-catalyzed Reactions (27 results)

EC NUMBER
REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
Arg-Gly-Phe + H2O = Arg + Gly-Phe
show the reaction diagram
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Gly-Gly-Phe + H2O = Gly + Gly-Phe
show the reaction diagram
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Met-S-Gly-Phe + H2O = Met + Gly-Phe
show the reaction diagram
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Gly-Gly-Phe + H2O = Gly + Gly-Phe
show the reaction diagram
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Gly-Phe 4-nitroanilide + H2O = Gly-Phe + 4-nitroaniline
show the reaction diagram
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Arg-Pro-Pro-Gly-Phe + H2O = Arg-Pro-Pro + Gly-Phe
show the reaction diagram
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Gly-Phe-4-nitroanilide + H2O = Gly-Phe + 4-nitroaniline
show the reaction diagram
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Phe-Gly-Gly-Phe + H2O = Phe-Gly + Gly-Phe
show the reaction diagram
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Gly-Phe-2-naphthylamide + H2O = Gly-Phe + 2-naphthylamine
show the reaction diagram
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Gly-Phe-Leu-Ala + H2O = Gly-Phe + Leu-Ala
show the reaction diagram
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Phenyloxycarbonyl-Gly-Leu-Gly-Phe + H2O = Phenyloxycarbonyl-Gly-Leu + Gly-Phe
show the reaction diagram
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Gly-Phe-NH2 + H2O = Gly-Phe + NH3
show the reaction diagram
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Activator in Enzyme-catalyzed Reactions (1 result)

EC NUMBER
COMMENTARY
LITERATURE
ENZYME 3D STRUCTURE
most effective D-amino acid and dipeptide acceptor, respectively
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Inhibitor in Enzyme-catalyzed Reactions (4 results)

EC NUMBER
COMMENTARY
LITERATURE
ENZYME 3D STRUCTURE
46% inhibition at 1 mM
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IC50: 10.471 mM
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Enzyme Kinetic Parameters

kcat Value (Turnover Number) (3 results)

EC NUMBER
TURNOVER NUMBER [1/S]
TURNOVER NUMBER MAXIMUM [1/S]
COMMENTARY
LITERATURE
0.5
-
Zn2+-Zn2+-enzyme form

KM Value (5 results)

EC NUMBER
KM VALUE [MM]
KM VALUE MAXIMUM [MM]
COMMENTARY
LITERATURE
1
-
Zn2+-Zn2+-enzyme form
0.99
-
-
1.7
-
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IC50 Value (1 result)

EC NUMBER
IC50 VALUE
IC50 VALUE MAXIMUM
COMMENTARY
LITERATURE
10.471
-
IC50: 10.471 mM

References & Links

Links to other databases for Gly-Phe

ChEBI
PubChem
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PubChem