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Ligand dihydro-4-coumaroyl-CoA Please wait a moment until all data is loaded. This message will disappear when all data is loaded.
Basic Ligand Information Molecular Structure
C3 0 H4 4 N7 O1 8 P3 S
dihydro-4-coumaroyl-CoA
KGYNXBHEANIYOS-FUEUKBNZSA-N
3-(4-hydroxyphenyl)-propionyl-CoA, 3-(4-hydroxyphenyl)propanoyl-CoA, 3-(4-hydroxyphenyl)propionyl-CoA, 4-hydroxyphenylpropanoyl-CoA, dihydro-p-coumaroyl-CoA, phloretyl-CoA
Roles as Enzyme Ligand
In Vivo Product in Enzyme-catalyzed Reactions (1 result)
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trans-4-coumaroyl-CoA + NADPH + H+ = dihydro-4-coumaroyl-CoA + NADP+
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Substrate in Enzyme-catalyzed Reactions (8 results)
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4-hydroxyphenylpropanoyl-CoA + 3-(3,4-dihydroxyphenyl)lactate = CoA + 2-O-(4-hydroxyphenylpropanoyl)-3-(3,4-dihydroxyphenyl)lactate
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4-hydroxyphenylpropanoyl-CoA + 3-(4-hydroxyphenyl)lactate = CoA + 2-O-(4-hydroxyphenylpropanoyl)-3-(4-hydroxyphenyl)lactate
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4-hydroxyphenylpropanoyl-CoA + 3-phenyllactate = CoA + 2-O-(4-hydroxyphenylpropanoyl)-3-phenyllactate
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4-hydroxyphenylpropanoyl-CoA + mandelate = CoA + 2-O-(4-hydroxyphenylpropanoyl)mandelate
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4-hydroxyphenylpropanoyl-CoA + tyrosol = CoA + 2-O-(4-hydroxyphenylpropanoyl)tyrosol
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(4-coumaroyl)acetyl-CoA + 3-(4-hydroxyphenyl)propionyl-CoA + H2O = 2 CoA + tetrahydrobisdemethoxycurcumin + CO2
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malonyl-CoA + dihydro-p-coumaroyl-CoA = ?
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dihydro-4-coumaroyl-CoA + malonyl-CoA = 3,4',5-trihydroxybibenzyl + CoA + CO2
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Product in Enzyme-catalyzed Reactions (3 results)
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trans-4-coumaroyl-CoA + NADPH + H+ = dihydro-4-coumaroyl-CoA + NADP+
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(E)-cinnamoyl-CoA + 3-(4-hydroxyphenyl)-propionate = (E)-cinnamate + 3-(4-hydroxyphenyl)-propionyl-CoA
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ATP + dihydro-4-coumarate + CoA = AMP + diphosphate + dihydro-4-coumaroyl-CoA
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Enzyme Kinetic Parameters
References & Links Literature References (4)
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Purification and properties of a stilbene synthase from induced cell suspension cultures of peanut
1984
Schöppner, A.; Kindl, H.
J. Biol. Chem.
259
6806-6811
Cloning and characterization of chalcone synthase from the moss, Physcomitrella patens
2006
Jiang, C.; Schommer, C.K.; Kim, S.Y.; Suh, D.Y.
Phytochemistry
67
2531-2540
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Identification of a new curcumin synthase from ginger and construction of a curcuminoid-producing unnatural fusion protein diketide-CoA synthase - curcumin synthase
2016
Zhang, L.; Gao, B.; Wang, X.; Zhang, Z.; Liu, X.; Wang, J.; Mo, T.; Liu, Y.; Shi, S.; Tu, P.
RSC Adv.
6
12519-12524
Synthesis of rosmarinic acid analogues in Escherichia coli
2016
Zhuang, Y.; Jiang, J.; Bi, H.; Yin, H.; Liu, S.; Liu, T.
Biotechnol. Lett.
38
619-627
Links to other databases for dihydro-4-coumaroyl-CoA