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Ligand (6E)-8-methylnon-6-enoyl-CoA

Basic Ligand Information

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Roles as Enzyme Ligand

In Vivo Substrate in Enzyme-catalyzed Reactions (1 result)

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Show Natural Substrate (1 entry)

EC NUMBER

PROVEN IN VIVO REACTION

REACTION DIAGRAM

LITERATURE

ENZYME 3D STRUCTURE

2.3.2.35

(6E)-8-methylnon-6-enoyl-CoA + vanillylamine = CoA + capsaicin

742723, 757779, 758008, 757493, 756306, 758210

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Substrate in Enzyme-catalyzed Reactions (1 result)

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Show Substrate (1 entry)

EC NUMBER

REACTION

REACTION DIAGRAM

LITERATURE

ENZYME 3D STRUCTURE

2.3.2.35

(6E)-8-methylnon-6-enoyl-CoA + vanillylamine = CoA + capsaicin

742723, 757779, 758008, 757493, 756306, 758210

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Enzyme Kinetic Parameters

K_M Value (1 result)

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Show KM Value (1 entry)

EC NUMBER

KM VALUE [MM]

KM VALUE MAXIMUM [MM]

COMMENTARY

LITERATURE

2.3.2.35

0.0082

-

at pH 6.8 and 37°C

758210

References & Links

Literature References (6)

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Show Reference (6 entries)

BRENDA REFERENCE ID

PUBMED ID

TITLE

YEAR

AUTHORS

JOURNAL

VOLUME

PAGES

742723

24984087

Enzymatic changes in phenylalanine ammonia-lyase, cinnamic-4-hydroxylase, capsaicin synthase, and peroxidase activities in capsicum under drought stress

2014

Phimchan, P.; Chanthai, S.; Bosland, P.W.; Techawongstien, S.

J. Agric. Food Chem.

62

7057-7062

756306

25884984

Evidence of capsaicin synthase activity of the Pun1-encoded protein and its role as a determinant of capsaicinoid accumulation in pepper

2015

Ogawa, K.; Murota, K.; Shimura, H.; Furuya, M.; Togawa, Y.; Matsumura, T.; Masuta, C.

BMC Plant Biol.

15

93

757493

12756913

Putrescine facilitated enhancement of capsaicin production in cell suspension cultures of Capsicum frutescens

2003

Sudha, G.; Ravishankar, G.A.

J. Plant Physiol.

160

339-346

757779

24441736

Genome sequence of the hot pepper provides insights into the evolution of pungency in Capsicum species

2014

Kim, S.; Park, M.; Yeom, S.I.; Kim, Y.M.; Lee, J.M.; Lee, H.A.; Seo, E.; Choi, J.; Cheong, K.; Kim, K.T.; Jung, K.; Lee, G.W.; Oh, S.K.; Bae, C.; Kim, S.B.; Lee, H.Y.; Kim, S.Y.; Kim, M.S.; Kang, B.C.; Jo, Y.D.; Yang, H.B.; Jeong, H.J.; Kang, W.H.; Kwon, J.K.; Shin, C.; Lim, J.Y.; Park, J.H.; Huh, J.H.; Kim, J.S.; Kim, B.D.; Cohen, O.; Paran, I.

Nat. Genet.

46

270-278

758008

15918882

The Pun1 gene for pungency in pepper encodes a putative acyltransferase

2005

Stewart Jr., C.; Kang, B.; Liu, K.; Mazourek, M.; Moore, S.; Eun, Y.; Kim, B.; Paran, I.; Jahn, M.

Plant J.

42

675-688

758210

16938870

Characterization of capsaicin synthase and identification of its gene (csy1) for pungency factor capsaicin in pepper (Capsicum sp.)

2006

Prasad, B.C.; Kumar, V.; Gururaj, H.B.; Parimalan, R.; Giridhar, P.; Ravishankar, G.A.

Proc. Natl. Acad. Sci. USA

103

13315-13320

Links to other databases for (6E)-8-methylnon-6-enoyl-CoA

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Show Links (1 entry)

ChEBI

PubChem

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