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Ligand UDP-2,3-diacetamido-2,3-dideoxy-alpha-D-glucuronate Please wait a moment until all data is loaded. This message will disappear when all data is loaded.
Basic Ligand Information Molecular Structure
C1 9 H2 8 N4 O1 8 P2
UDP-2,3-diacetamido-2,3-dideoxy-alpha-D-glucuronate
GZLIMKLKXDFTJR-LTMKHLKMSA-N
Roles as Enzyme Ligand
In Vivo Substrate in Enzyme-catalyzed Reactions (2 results)
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UDP-2,3-diacetamido-2,3-dideoxy-alpha-D-glucuronate + dolichyl N-acetyl-alpha-D-glucosaminyl phosphate = UDP + dolichyl 3-O-(2,3-diacetamido-2,3-dideoxy-beta-D-glucuronsyl)-N-acetyl-alpha-D-glucosaminyl phosphate
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UDP-2,3-diacetamido-2,3-dideoxy-alpha-D-glucuronate = UDP-2,3-diacetamido-2,3-dideoxy-alpha-D-mannuronate
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In Vivo Product in Enzyme-catalyzed Reactions (1 result)
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acetyl-CoA + UDP-2-acetamido-3-amino-2,3-dideoxy-alpha-D-glucuronate = CoA + UDP-2,3-diacetamido-2,3-dideoxy-alpha-D-glucuronate
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Substrate in Enzyme-catalyzed Reactions (2 results)
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UDP-2,3-diacetamido-2,3-dideoxy-alpha-D-glucuronate + dolichyl N-acetyl-alpha-D-glucosaminyl phosphate = UDP + dolichyl 3-O-(2,3-diacetamido-2,3-dideoxy-beta-D-glucuronsyl)-N-acetyl-alpha-D-glucosaminyl phosphate
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UDP-2,3-diacetamido-2,3-dideoxy-alpha-D-glucuronate = UDP-2,3-diacetamido-2,3-dideoxy-alpha-D-mannuronate
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Product in Enzyme-catalyzed Reactions (1 result)
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acetyl-CoA + UDP-2-acetamido-3-amino-2,3-dideoxy-alpha-D-glucuronate = CoA + UDP-2,3-diacetamido-2,3-dideoxy-alpha-D-glucuronate
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Enzyme Kinetic Parameters
References & Links Literature References (2)
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Identification and biochemical characterization of two novel UDP-2,3-diacetamido-2,3-dideoxy-alpha -D-glucuronic acid 2-epimerases from respiratory pathogens
2007
Westman, E.L.; McNally, D.J.; Rejzek, M.; Miller, W.L.; Kannathasan, V.S.; Preston, A.; Maskell, D.J.; Field, R.A.; Brisson, J.R.; Lam, J.S.
Biochem. J.
405
123-130
Biochemical evidence for an alternate pathway in N-linked glycoprotein biosynthesis
2013
Larkin, A.; Chang, M.M.; Whitworth, G.E.; Imperiali, B.
Nat. Chem. Biol.
9
367-373
Links to other databases for UDP-2,3-diacetamido-2,3-dideoxy-alpha-D-glucuronate