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wild-type enzyme, FMO3
0.145
-
wild-type enzyme, FMO1
0.34
-
mutant enzyme R502X, FMO1
0.3
-
mutant enzyme K158L/D132H, FMO3
0.22
-
mutant enzyme K158L, FMO3
0.2
-
mutant enzyme I303V, FMO1
0.351
-
mutant enzyme I303T, FMO1
0.24
-
mutant enzyme H97Q, FMO1
0.32
-
mutant enzyme D132H, FMO3
0.15
-
CYP3A4, sulfoxidation to fenthion-sulfoxide
0.131
-
sulfoxidation to fenthion-sulfoxide
0.01
-
sulfoxidation to fenthion-sulfoxide
0.0022
-
desulfuration by recombinant human CYPs to fenthion-oxon
0.0027
-
desulfuration by recombinant human CYPs to fenthion-oxon
0.0016
-
sulfoxidation to fenthion-sulfoxide
desulfuration by recombinant human CYPs to fenthion-oxon
CYP1A1, at pH 7.4 and 37°C
0.008
-
CYP3A4, desulfuration by recombinant human CYPs to fenthion-oxon
0.089
-
CYP3A4, at pH 7.4 and 37°C
0.131
-
CYP3A4, at pH 7.4 and 37°C
0.089
-
CYP3A4, at pH 7.4 and 37°C
CYP2C9, sulfoxidation to fenthion-sulfoxide
0.006
-
CYP2C9, desulfuration by recombinant human CYPs to fenthion-oxon
0.012
-
CYP2C9, at pH 7.4 and 37°C
0.012
-
CYP2C9, at pH 7.4 and 37°C
0.006
-
CYP2C9, at pH 7.4 and 37°C
CYP2C19, sulfoxidation to fenthion-sulfoxide
0.0044
-
CYP2C19, desulfuration by recombinant human CYPs to fenthion-oxon
0.0024
-
CYP2C19, at pH 7.4 and 37°C
0.0044
-
CYP2C19, at pH 7.4 and 37°C
0.0024
-
CYP2C19, at pH 7.4 and 37°C
CYP1A1, sulfoxidation to fenthion-sulfoxide
0.008
-
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