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Ligand ethyl 4-hydroxy-3-methoxycinnamate

Basic Ligand Information

Molecular Structure

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Roles as Enzyme Ligand

Substrate in Enzyme-catalyzed Reactions (2 results)

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Show Substrate (2 entries)

EC NUMBER

REACTION

REACTION DIAGRAM

LITERATURE

ENZYME 3D STRUCTURE

3.1.1.20

ferulic ethyl ester + H2O = ethanol + ferulate

729042, 729082

-

3.1.1.73

ferulic acid ethyl ester + H2O = ferulic acid + ethanol

737924, 737894

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Inhibitor in Enzyme-catalyzed Reactions (1 result)

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Show Inhibitors (1 entry)

EC NUMBER

COMMENTARY

LITERATURE

ENZYME 3D STRUCTURE

1.4.3.4

IC50: 0.0057 mM, monoamine oxidase B; IC50: 0.0247 mM, monoamine oxidase A

672530

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Enzyme Kinetic Parameters

k_cat Value (Turnover Number) (1 result)

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Show Turnover Number (1 entry)

EC NUMBER

TURNOVER NUMBER [1/S]

TURNOVER NUMBER MAXIMUM [1/S]

COMMENTARY

LITERATURE

3.1.1.73

0.9

-

pH 8.8, 40°C

737924

K_M Value (1 result)

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Show KM Value (1 entry)

EC NUMBER

KM VALUE [MM]

KM VALUE MAXIMUM [MM]

COMMENTARY

LITERATURE

3.1.1.73

0.5

-

pH 8.8, 40°C

737924

IC₅₀ Value (2 results)

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Show IC50 Value (2 entries)

EC NUMBER

IC50 VALUE

IC50 VALUE MAXIMUM

COMMENTARY

LITERATURE

1.4.3.4

0.0057

-

IC50: 0.0057 mM, monoamine oxidase B

672530

1.4.3.4

0.0247

-

IC50: 0.0247 mM, monoamine oxidase A

672530

1.4.3.4

2 entries

References & Links

Literature References (5)

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Show Reference (5 entries)

BRENDA REFERENCE ID

PUBMED ID

TITLE

YEAR

AUTHORS

JOURNAL

VOLUME

PAGES

672530

15936201

Eugenol and its structural analogs inhibit monoamine oxidase A and exhibit antidepressant-like activity

2005

Tao, G.; Irie, Y.; Li, D.J.; Keung, W.M.

Bioorg. Med. Chem.

13

4777-4788

729042

24610854

Tannin degradation by a novel tannase enzyme present in some Lactobacillus plantarum strains

2014

Jimenez, N.; Esteban-Torres, M.; Mancheno, J.M.; de Las Rivas, B.; Munoz, R.

Appl. Environ. Microbiol.

80

2991-2997

729082

24577784

Characterization of a bacterial tannase from Streptococcus gallolyticus UCN34 suitable for tannin biodegradation

2014

Jimenez, N.; Barcenilla, J.M.; de Felipe, F.L.; de Las Rivas, B.; Munoz, R.

Appl. Microbiol. Biotechnol.

98

6329-6337

737894

26272349

Heterologous production of a feruloyl esterase from Pleurotus sapidus synthesizing feruloyl-saccharide esters

2015

Kelle, S.; Nieter, A.; Krings, U.; Zelena, K.; Linke, D.; Berger, R.

Biotechnol. Appl. Biochem.

63

852-862

737924

26956238

Discovery of novel feruloyl esterase activity of BioH in Escherichia coli BL21(DE3)

2016

Kang, L.; Bai, Y.; Cai, Y.; Zheng, X.

Biotechnol. Lett.

38

1009-1013

Links to other databases for ethyl 4-hydroxy-3-methoxycinnamate

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Show Links (1 entry)

ChEBI

PubChem

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