Ligand CDP-glucose

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Basic Ligand Information

Molecular Structure
Picture of CDP-glucose (click for magnification)
Molecular Formula
BRENDA Name
InChIKey
C15H25N3O16P2
CDP-glucose
CGPHZDRCVSLMCF-JZMIEXBBSA-N
Synonyms:
CDP-alpha-D-glucose, CDP-D-glucose, CDPglucose

Roles as Enzyme Ligand

In Vivo Substrate in Enzyme-catalyzed Reactions (2 results)

EC NUMBER
PROVEN IN VIVO REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
CDP-glucose + H2O = CMP + D-glucose-1-phosphate
show the reaction diagram
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CDP-glucose = ?
show the reaction diagram
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In Vivo Product in Enzyme-catalyzed Reactions (1 result)

EC NUMBER
PROVEN IN VIVO REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
CTP + alpha-D-glucose 1-phosphate = diphosphate + CDP-glucose
show the reaction diagram
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Substrate in Enzyme-catalyzed Reactions (25 results)

EC NUMBER
REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
CDP-glucose + NAD+ + H2O = CDP-glucuronate + NADH
show the reaction diagram
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CDP-glucose + D-glucose 6-phosphate = trehalose 6-phosphate + CDP
show the reaction diagram
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CDP-glucose + hydroquinone = CDP + hydroquinone-O-beta-D-glucopyranoside
show the reaction diagram
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CDP-glucose + (1,4-alpha-glucosyl)n = CDP + ?
show the reaction diagram
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CDP-alpha-D-glucose + D-glucose = alpha,alpha-trehalose + CDP
show the reaction diagram
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CDP-glucose + p-nitrophenol = CDP + p-nitrophenyl beta-D-glucoside
show the reaction diagram
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CDP-glucose + N-acylsphingosine = CDP + D-glucosyl-N-acylsphingosine
show the reaction diagram
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CDP-glucose + 4',7-dihydroxyflavone = CDP + 7-O-beta-D-glucosyl-4',7-dihydroxyflavone
show the reaction diagram
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CDP-glucose + alpha-D-galactose 1-phosphate = alpha-D-glucose 1-phosphate + CDP-galactose
show the reaction diagram
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diphosphate + CDP-glucose = CTP + alpha-D-glucose 1-phosphate
show the reaction diagram
diphosphate + CDP-glucose = CTP + alpha-D-glucose 1-phosphate
show the reaction diagram
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CDP-glucose + H2O = CMP + glucose 5-phosphate
show the reaction diagram
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CDP-D-glucose = ?
show the reaction diagram
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Product in Enzyme-catalyzed Reactions (8 results)

EC NUMBER
REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
CDP + sucrose = CDP-alpha-D-glucose + D-fructose
show the reaction diagram
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alpha,alpha-trehalose + CDP = CDP-alpha-D-glucose + D-glucose
show the reaction diagram
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CTP + alpha-D-glucose 1-phosphate = diphosphate + CDP-alpha-D-glucose
show the reaction diagram
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Inhibitor in Enzyme-catalyzed Reactions (9 results)

EC NUMBER
COMMENTARY
LITERATURE
ENZYME 3D STRUCTURE
competitive against UDP-N-acetyl-D-glucosamine
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slight inhibition
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product inhibition, competitive with respect to CTP, kinetics
inhibits uridylyl removing activity
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competitive
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3D Structure of Enzyme-Ligand-Complex (PDB) (1 result)

EC NUMBER
ENZYME 3D STRUCTURE

Enzyme Kinetic Parameters

kcat Value (Turnover Number) (4 results)

EC NUMBER
TURNOVER NUMBER [1/S]
TURNOVER NUMBER MAXIMUM [1/S]
COMMENTARY
LITERATURE
125
-
pH 6.0, 37°C

KM Value (12 results)

EC NUMBER
KM VALUE [MM]
KM VALUE MAXIMUM [MM]
COMMENTARY
LITERATURE
0.33
-
-

Ki Value (2 results)

EC NUMBER
KI VALUE [MM]
KI VALUE MAXIMUM [MM]
COMMENTARY
LITERATURE
3.9
-
recombinant enzyme
0.35
-
pH 8.5, 37°C

References & Links

Links to other databases for CDP-glucose

ChEBI
PubChem
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PubChem