Ligand reduced NADPH-cytochrome P450 reductase
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Basic Ligand Information
reduced NADPH-cytochrome P450 reductase
Roles as Enzyme Ligand
Substrate in Enzyme-catalyzed Reactions (1 result)
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squalene + reduced NADPH-cytochrome P450 reductase + O2 = (3S)-2,3-epoxy-2,3-dihydrosqualene + oxidized NADPH-cytochrome P450 reductase + H2O
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Enzyme Kinetic Parameters
KM Value (1 result)
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0.000014
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recombinant enzyme, Km for electron transfer partner NADPH-cytochrone P 450 reductase
References & Links
Literature References (1)
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Cloning, heterologous expression, and enzymological characterization of human squalene monooxygenase
2000
Laden, B.P.; Tang, Y.; Porter, T.D.
Arch. Biochem. Biophys.
374
381-388
Links to other databases for reduced NADPH-cytochrome P450 reductase