Ligand [histone H3]-N6,N6-dimethyl-L-lysine27

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Basic Ligand Information

Molecular Formula
BRENDA Name
InChIKey
[histone H3]-N6,N6-dimethyl-L-lysine27

Roles as Enzyme Ligand

In Vivo Substrate in Enzyme-catalyzed Reactions (2 results)

EC NUMBER
PROVEN IN VIVO REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
[histone H3]-N6,N6-dimethyl-L-lysine27 + 2-oxoglutarate + O2 = [histone H3]-N6-methyl-L-lysine27 + succinate + formaldehyde + CO2
show the reaction diagram
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S-adenosyl-L-methionine + [histone H3]-N6,N6-dimethyl-L-lysine27 = S-adenosyl-L-homocysteine + [histone H3]-N6,N6,N6-trimethyl-L-lysine27
show the reaction diagram
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In Vivo Product in Enzyme-catalyzed Reactions (2 results)

EC NUMBER
PROVEN IN VIVO REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
S-adenosyl-L-methionine + [histone H3]-N6-methyl-L-lysine27 = S-adenosyl-L-homocysteine + [histone H3]-N6,N6-dimethyl-L-lysine27
show the reaction diagram
-
-
S-adenosyl-L-methionine + [histone H3]-N6-methyl-L-lysine27 = S-adenosyl-L-homocysteine + [histone H3]-N6,N6-dimethyl-L-lysine27
show the reaction diagram
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-

Substrate in Enzyme-catalyzed Reactions (2 results)

EC NUMBER
REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
[histone H3]-N6,N6-dimethyl-L-lysine27 + 2-oxoglutarate + O2 = [histone H3]-N6-methyl-L-lysine27 + succinate + formaldehyde + CO2
show the reaction diagram
-
S-adenosyl-L-methionine + [histone H3]-N6,N6-dimethyl-L-lysine27 = S-adenosyl-L-homocysteine + [histone H3]-N6,N6,N6-trimethyl-L-lysine27
show the reaction diagram
-

Product in Enzyme-catalyzed Reactions (2 results)

EC NUMBER
REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
S-adenosyl-L-methionine + [histone H3]-N6-methyl-L-lysine27 = S-adenosyl-L-homocysteine + [histone H3]-N6,N6-dimethyl-L-lysine27
show the reaction diagram
-
-
S-adenosyl-L-methionine + [histone H3]-N6-methyl-L-lysine27 = S-adenosyl-L-homocysteine + [histone H3]-N6,N6-dimethyl-L-lysine27
show the reaction diagram
-
-

Enzyme Kinetic Parameters

References & Links

Links to other databases for [histone H3]-N6,N6-dimethyl-L-lysine27

ChEBI
PubChem
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