Ligand N-linolenoylethanolamide
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Basic Ligand Information
Molecular Structure

C20H35NO2
N-linolenoylethanolamide
HBJXRRXWHSHZPU-PDBXOOCHSA-N
N-(alpha-linolenoyl)ethanolamine, N-alpha-linolenoylethanolamide
Roles as Enzyme Ligand
In Vivo Substrate in Enzyme-catalyzed Reactions (1 result)
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N-alpha-linolenoylethanolamide + H2O = alpha-linoleate + ethanolamine
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Substrate in Enzyme-catalyzed Reactions (2 results)
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N-linolenoylethanolamide + O2 = ?
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N-alpha-linolenoylethanolamide + H2O = alpha-linoleate + ethanolamine
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Activator in Enzyme-catalyzed Reactions (1 result)
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Enzyme Kinetic Parameters
KM Value (1 result)
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0.015
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in 0.1 M borate (pH 9.0), temperature not specified in the publication
References & Links
Literature References (3)
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Lauroylethanolamide is a potent competitive inhibitor of lipoxygenase activity
2010
Keereetaweep, J.; Kilaru, A.; Feussner, I.; Venables, B.J.; Chapman, K.D.
FEBS Lett.
584
3215-3222
N-acylethanolamines bind to SIRT6
2016
Rahnasto-Rilla, M.; Kokkola, T.; Jarho, E.; Lahtela-Kakkonen, M.; Moaddel, R.
ChemBioChem
17
77-81
Development of new inhibitors for N-acylethanolamine-hydrolyzing acid amidase as promising tool against bladder cancer
2017
Vago, R.; Bettiga, A.; Salonia, A.; Ciuffreda, P.; Ottria, R.
Bioorg. Med. Chem.
25
1242-1249
Links to other databases for N-linolenoylethanolamide