Ligand 5-methylaminomethyl-2-(S-geranyl)thiouridine34 in tRNA
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Basic Ligand Information
5-methylaminomethyl-2-(S-geranyl)thiouridine34 in tRNA
Roles as Enzyme Ligand
Substrate in Enzyme-catalyzed Reactions (1 result)
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selenophosphate + 5-methylaminomethyl-2-(S-geranyl)thiouridine34 in tRNA = 5-methylaminomethyl-2-(Se-phospho)selenouridine34 in tRNA + (2E)-3,7-dimethylocta-2,6-diene-1-thiol
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Product in Enzyme-catalyzed Reactions (1 result)
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geranyl diphosphate + 5-methylaminomethyl-2-thiouridine34 in tRNA = 5-methylaminomethyl-2-(S-geranyl)thiouridine34 in tRNA + diphosphate
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Enzyme Kinetic Parameters
References & Links
Literature References (2)
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Escherichia coli tRNA 2-selenouridine synthase (SelU) converts S2U-RNA to Se2U-RNA via S-geranylated-intermediate
2018
Sierant, M.; Leszczynska, G.; Sadowska, K.; Komar, P.; Radzikowska-Cieciura, E.; Sochacka, E.; Nawrot, B.
FEBS Lett.
592
2248-2258
Transfer RNA bound to mnmh protein is enriched with geranylated tRNA-a possible intermediate in its selenation
2016
Jager, G.; Chen, P.; Bjork, G.R.
PLoS One
11
e0153488
Links to other databases for 5-methylaminomethyl-2-(S-geranyl)thiouridine34 in tRNA