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Ligand aureobasidin A
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Basic Ligand Information
MetaCyc
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Inhibitor in Enzyme-catalyzed Reactions (10 results)
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EC NUMBER 
COMMENTARY
LITERATURE
ENZYME 3D STRUCTURE
IC50 value 2.1 ng/ml. All Candida species tested are well susceptible to aureobasidin A with MICs below 2 microg/ml
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IC50 value 2.5 ng/ml. All Candida species tested are well susceptible to aureobasidin A with MICs below 2 microg/ml
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IC50 value 2.6 ng/ml. Strain is intrinsically resistant to aureobasidin A (MIC above 50 microg/ml), but has IPC synthase activity sensitive to aureobasidin A
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IC50 value 3.4 ng/ml. All Candida species tested are well susceptible to aureobasidin A with MICs below 2 microg/ml
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inhibits Aur1, activates vacuolar acidification and strongly induces the cell wall integrity pathway
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strongly inhibits the activity of IPC synthase in wild-type, which leads to distinct changes in cell morphology, including the delay in conidial germination, excessive branching near the tip of the germ tube and mycelium, and the inhibition of the mycelium growth. Aureobasidin A prevents the infection of wild-type in tomato fruits via reducing oxalic acid secretion and the activity of cellulase and pectinase
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Enzyme Kinetic Parameters
Ki Value (2 results)
EC NUMBER
KI VALUE [MM]
KI VALUE MAXIMUM [MM]
COMMENTARY
LITERATURE
IC50 Value (2 results)
EC NUMBER
IC50 VALUE
IC50 VALUE MAXIMUM
COMMENTARY
LITERATURE
References & Links
Literature References (7)
Links to other databases for aureobasidin A
ChEBI
PubChem
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