Ligand 1-myristin

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Basic Ligand Information

Molecular Structure
Picture of 1-myristin (click for magnification)
Molecular Formula
BRENDA Name
InChIKey
C17H34O4
1-myristin
DCBSHORRWZKAKO-UHFFFAOYSA-N
Synonyms:
1-monomyristoyl-glycerol, 1-monomyristoyl-rac-glycerol, 1-monomyristoylglycerol, 1-myristoyl-rac-glycerol, 1-myristoylglycerol, glycerol myristate, monomyristin, monomyristoylglycerol

Roles as Enzyme Ligand

Substrate in Enzyme-catalyzed Reactions (8 results)

EC NUMBER
REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
ATP + 1-myristoylglycerol = ADP + 1-myristoylglycerol 3-phosphate
show the reaction diagram
-
1-monomyristoyl-glycerol + H2O = myristic acid + glycerol
show the reaction diagram
-
glycerol myristate + H2O = glycerol + myristate
show the reaction diagram
-

Product in Enzyme-catalyzed Reactions (2 results)

EC NUMBER
REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
glycerol + myristic acid = monomyristin + H2O
show the reaction diagram
-
-
1-myristoyl-sn-glycerol 3-phosphate + H2O = 1-myristoylglycerol + phosphate
show the reaction diagram
-
-

Inhibitor in Enzyme-catalyzed Reactions (3 results)

EC NUMBER
COMMENTARY
LITERATURE
ENZYME 3D STRUCTURE
IC50 in the range 1-100 mM
-
IC50 value for the membraneous and the cytosolic enzyme is 0.032 mM, complete inhibition is possible
-
IC50: 0.018, complete inhibition is possible
-

Enzyme Kinetic Parameters

KM Value (1 result)

EC NUMBER
KM VALUE [MM]
KM VALUE MAXIMUM [MM]
COMMENTARY
LITERATURE
0.12
-
-

IC50 Value (3 results)

EC NUMBER
IC50 VALUE
IC50 VALUE MAXIMUM
COMMENTARY
LITERATURE
1
100
IC50 in the range 1-100 mM
0.032
-
IC50 value for the membraneous and the cytosolic enzyme is 0.032 mM, complete inhibition is possible
0.018
-
IC50: 0.018 mM, complete inhibition is possible

References & Links

Links to other databases for 1-myristin

ChEBI
PubChem
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PubChem