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BRENDA support

Ligand antithrombin III

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Basic Ligand Information

Molecular Formula
BRENDA Name
InChIKey
antithrombin III

Roles as Enzyme Ligand

In Vivo Substrate in Enzyme-catalyzed Reactions (1 result)

EC NUMBER
PROVEN IN VIVO REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
Antithrombin III + H2O = ?
show the reaction diagram
-

Substrate in Enzyme-catalyzed Reactions (5 results)

EC NUMBER
REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
Antithrombin III + H2O = ?
show the reaction diagram
-
Antithrombin III + H2O = ?
show the reaction diagram
-
Antithrombin III + H2O = ?
show the reaction diagram
-
Antithrombin III + H2O = ?
show the reaction diagram
-
thrombospondin-1 + alpha-thrombin + antithrombin III = thrombospondin-1-S-S-alpha-thrombin-S-S-antithrombin III
show the reaction diagram
-

Inhibitor in Enzyme-catalyzed Reactions (25 results)

EC NUMBER
COMMENTARY
LITERATURE
ENZYME 3D STRUCTURE
most efficient endogenous inhibitor
-
50% inhibition at 0.8 microM in 6 min
-
inhibitory in the presence of heparin on activity of MASP-1
-

Enzyme Kinetic Parameters

Ki Value (2 results)

EC NUMBER
KI VALUE [MM]
KI VALUE MAXIMUM [MM]
COMMENTARY
LITERATURE
0.0000014
-
pH 7.4, 37°C
0.0091
-
-

References & Links

Links to other databases for antithrombin III

EXTERNAL LINKS