Ligand ubiquinone-2

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Basic Ligand Information

Molecular Structure
Picture of ubiquinone-2 (click for magnification)
Molecular Formula
BRENDA Name
InChIKey
C19H26O4
ubiquinone-2
SQQWBSBBCSFQGC-JLHYYAGUSA-N
Synonyms:
2,3-dimethoxy-5-methyl-6-geranyl-1,4-benzoquinone, coenzyme Q2, oxidized coenzyme Q2, ubiqinone-2, ubiquinone 2, ubiquinone Q2

Roles as Enzyme Ligand

In Vivo Product in Enzyme-catalyzed Reactions (3 results)

EC NUMBER
PROVEN IN VIVO REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
2 ubiquinol-2 + O2 = 2 ubiquinone-2 + 2 H2O
show the reaction diagram
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Substrate in Enzyme-catalyzed Reactions (20 results)

EC NUMBER
REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
sn-glycerol 3-phosphate + coenzyme Q2 = glycerone phosphate + reduced coenzyme Q2
show the reaction diagram
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D-sorbitol + ubiquinone-2 = ?
show the reaction diagram
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superoxide + ubiquinone Q2 + H+ = O2 + ubiquinol Q2
show the reaction diagram
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N-benzyldihydronicotinamide + oxidized coenzyme Q2 = N-benzylnicotinamide + reduced coenzyme Q2
show the reaction diagram
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reduced electron-transferring flavoprotein + ubiquinone-2 = electron-transferring flavoprotein + ubiquinol-2
show the reaction diagram
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NADH + H+ + ubiquinone-2 = NAD+ + ubiquinol-2
show the reaction diagram
sulfide + ubiquinone-2 = sulfur + ubiquinol-2
show the reaction diagram
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Product in Enzyme-catalyzed Reactions (8 results)

EC NUMBER
REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
2 ubiquinol-2 + O2 = 2 ubiquinone-2 + 2 H2O
show the reaction diagram
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nicotinamide riboside + reduced coenzyme Q2 = dihydronicotinamide riboside + coenzyme Q2
show the reaction diagram
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ubiquinol-2 + O2 + H+[side 1] = ubiquinone-2 + H2O + H+[side 2]
show the reaction diagram
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Enzyme Cofactor/Cosubstrate (2 results)

EC NUMBER
COMMENTARY
LITERATURE
ENZYME 3D STRUCTURE
electron acceptor
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0.2 mM quinone stimulates reaction with D-alanine and oxidized 2,6-dichloroindophenol 26fold
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Inhibitor in Enzyme-catalyzed Reactions (1 result)

EC NUMBER
COMMENTARY
LITERATURE
ENZYME 3D STRUCTURE
product inhibition
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3D Structure of Enzyme-Ligand-Complex (PDB) (51 results)

Enzyme Kinetic Parameters

kcat Value (Turnover Number) (3 results)

EC NUMBER
TURNOVER NUMBER [1/S]
TURNOVER NUMBER MAXIMUM [1/S]
COMMENTARY
LITERATURE
640
-
pH 7.0, temperature not specified in the publication

KM Value (27 results)

EC NUMBER
KM VALUE [MM]
KM VALUE MAXIMUM [MM]
COMMENTARY
LITERATURE
0.023
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0.0257
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0.0387
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using N-benzyl dihydronicotinamide as cosubstrate, at 25°C, in 50 mM Tris-HCl, pH 8.5
0.0079
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in 50 mM sodium phosphate buffer (pH 6.0) and 1 mM EDTA, temperature not specified in the publication
0.014
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apparent value, at pH 7.0, temperature not specified in the publication

References & Links

Links to other databases for ubiquinone-2

ChEBI
PubChem
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PubChem