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Ligand HLKSKKGQSTSRHK(K-Ac)LMFK Please wait a moment until all data is loaded. This message will disappear when all data is loaded.
Basic Ligand Information Molecular Structure
C1 0 2 H1 7 5 N3 3 O2 6 S
HLKSKKGQSTSRHK(K-Ac)LMFK
BBWLGWPIULFHLA-OOAXPKAFSA-N
Roles as Enzyme Ligand
Substrate in Enzyme-catalyzed Reactions (1 result)
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HLKSKKGQSTSRHK(K-Ac)LMFK + NAD+ + H2O = HLKSKKGQSTSRHKKLMFK + 2''-O-acetyl-ADP-D-ribose + nicotinamide
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Enzyme Kinetic Parameters
References & Links Literature References (1)
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Transition state of ADP-ribosylation of acetyllysine catalyzed by Archaeoglobus fulgidus Sir2 determined by kinetic isotope effects and computational approaches
2010
Cen, Y.; Sauve, A.A.
J. Am. Chem. Soc.
132
12286-12298
Links to other databases for HLKSKKGQSTSRHK(K-Ac)LMFK