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Basic Ligand Information
Roles as Enzyme Ligand
Enzyme Kinetic Parameters
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Ligand N-methyldihydronicotinamide

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Basic Ligand Information

Molecular Structure

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Molecular Formula

BRENDA Name

InChIKey

C₇H₁₀N₂O

N-methyldihydronicotinamide

YVLIYQJWVPMVPQ-UHFFFAOYSA-N

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Roles as Enzyme Ligand

Substrate in Enzyme-catalyzed Reactions (4 results)

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Show Substrate (4 entries)

EC NUMBER

REACTION

REACTION DIAGRAM

LITERATURE

ENZYME 3D STRUCTURE

1.10.5.1

N-methyldihydronicotinamide + 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide = N-methylnicotinamide + ?

724559

1.10.5.1

N-methyldihydronicotinamide + 3-hydroxy-1-methylindoline-5,6-dione = N-methylnicotinamide + 3-hydroxy-1-methylindoline-5,6-diol

698793

1.10.5.1

N-methyldihydronicotinamide + menadione = ?

659968, 660397, 657888

1.10.5.1

N-methyldihydronicotinamide + menadione = N-methylnicotinamide + menadiol

724559, 696093

1.10.5.1

4 entries

Enzyme Kinetic Parameters

References & Links

Literature References (6)

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Show Reference (6 entries)

BRENDA REFERENCE ID

PUBMED ID

TITLE

YEAR

AUTHORS

JOURNAL

VOLUME

PAGES

657888

16253210

NRH:quinone reductase 2: an enzyme of surprises and mysteries

2005

Vella, F.; Ferry, G.; Delagrange, P.; Boutin, J.A.

Biochem. Pharmacol.

1-12

659968

12435804

Discovery of novel targets of quinoline drugs in the human purine binding proteome

2002

Graves, P.R.; Kwiek, J.J.; Fadden, P.; et al.

Mol. Pharmacol.

1364-1372

660397

9050836

Unexpected genetic and structural relationships of a long-forgotten flavoenzyme to NAD(P)H:quinone reductase (DT-diaphorase)

1997

Zhao, Q.; Yang, X.L.; Holtzclaw, W.D.; Talalay, P.

Proc. Natl. Acad. Sci. USA

1669-1674

696093

18254726

Kinetic, thermodynamic and X-ray structural insights into the interaction of melatonin and analogues with quinone reductase 2

2008

Calamini, B.; Santarsiero, B.D.; Boutin, J.A.; Mesecar, A.D.

Biochem. J.

413

81-91

698793

18579530

Quinone reductase 2 is a catechol quinone reductase

2008

Fu, Y.; Buryanovskyy, L.; Zhang, Z.

J. Biol. Chem.

283

23829-23835

724559

23953689

Design, synthesis, biological and structural evaluation of functionalized resveratrol analogues as inhibitors of quinone reductase 2

2013

John, S.E.St.; Jensen, K.C.; Kang, S.; Chen, Y.; Calamini, B.; Mesecar, A.D.; Lipton, M.A.

Bioorg. Med. Chem.

6022-6037

Links to other databases for N-methyldihydronicotinamide

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Show Links (1 entry)

ChEBI

PubChem