Ligand Ngamma-monomethyl-L-arginine

Please wait a moment until all data is loaded. This message will disappear when all data is loaded.

Basic Ligand Information

Molecular Structure
Picture of Ngamma-monomethyl-L-arginine (click for magnification)
Molecular Formula
BRENDA Name
InChIKey
C7H16N4O2
Ngamma-monomethyl-L-arginine
NTNWOCRCBQPEKQ-YFKPBYRVSA-N
Synonyms:
(2S)-2-amino-5-(N'-methylcarbamimidamido)pentanoic acid, L-omega-monomethyl L-arginine, N-monomethyl-L-arginine, N5-(methylcarbamimidoyl)-L-ornithine, N5-(N-methylcarbamimidoyl)-L-ornithine, NG,NG-monomethyl-L-arginine, NG-methyl-L-arginine, NG-methyl arginine, NG-methylarginine, Ng-monomethy-L-arginine, NG-monomethyl-L-arginine, NG-monomethylarginine, Ngamma-amino-L-arginine, Ngamma-methyl-L-arginine, Ngamma-monomethyl-L-Arg, Nomega-methyl-Arg, Nomega-methyl-L-arginine, Nomega-monomethyl-L-arginine

Roles as Enzyme Ligand

Substrate in Enzyme-catalyzed Reactions (12 results)

EC NUMBER
REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
Ngamma-monomethyl-L-Arg = N-(3-aminopropyl)-N'-methylguanidine + CO2
show the reaction diagram
-
ATP + NG-methyl-L-arginine + tRNACCCG = AMP + diphosphate + L-arginyl-tRNACCCG
show the reaction diagram
-

Inhibitor in Enzyme-catalyzed Reactions (16 results)

EC NUMBER
COMMENTARY
LITERATURE
ENZYME 3D STRUCTURE
1 mM, 14% inhibition
-
poor arginase 1 inhibitor
-

3D Structure of Enzyme-Ligand-Complex (PDB) (116 results)

EC NUMBER
ENZYME 3D STRUCTURE

Enzyme Kinetic Parameters

kcat Value (Turnover Number) (7 results)

EC NUMBER
TURNOVER NUMBER [1/S]
TURNOVER NUMBER MAXIMUM [1/S]
COMMENTARY
LITERATURE
1.22
-
pH 7.5, 37°C

KM Value (10 results)

EC NUMBER
KM VALUE [MM]
KM VALUE MAXIMUM [MM]
COMMENTARY
LITERATURE
0.163
-
pH 7.5, 37°C

Ki Value (11 results)

EC NUMBER
KI VALUE [MM]
KI VALUE MAXIMUM [MM]
COMMENTARY
LITERATURE

References & Links

Links to other databases for Ngamma-monomethyl-L-arginine

ChEBI
PubChem
-
PubChem