Ligand ginsenoside Rg1

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Basic Ligand Information

Molecular Structure
Picture of ginsenoside Rg1 (click for magnification)
Molecular Formula
BRENDA Name
InChIKey
C42H72O14
ginsenoside Rg1
YURJSTAIMNSZAE-HHNZYBFYSA-N
Synonyms:
(20S)-ginsenoside Rg1
Pathway Source
Pathways


Show all pahtways known for Show all BRENDA pathways known for ginsenoside Rg1

Roles as Enzyme Ligand

In Vivo Substrate in Enzyme-catalyzed Reactions (5 results)

EC NUMBER
PROVEN IN VIVO REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
ginsenoside Rg1 + H2O = ginsenoside Rh1 + D-glucose
show the reaction diagram
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ginsenoside Rg1 + H2O = protopanaxatriol + 2 D-glucose
show the reaction diagram
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ginsenoside Rg1 + H2O = ginsenoside Rh1 + D-glucose
show the reaction diagram
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In Vivo Product in Enzyme-catalyzed Reactions (4 results)

EC NUMBER
PROVEN IN VIVO REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
UDP-alpha-D-glucose + ginsenoside F1 = UDP + (20S)-ginsenoside Rg1
show the reaction diagram
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UDP-alpha-D-glucose + ginsenoside F1 = UDP + (20S)-ginsenoside Rg1
show the reaction diagram
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Substrate in Enzyme-catalyzed Reactions (8 results)

EC NUMBER
REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
UDP-galactose + ginsenoside Rg1 = UDP + beta-D-galactosyl-1,4-ginsenoside Rg1
show the reaction diagram
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UDP-galactose + ginsenoside Rg1 = ?
show the reaction diagram
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ginsenoside Rg1 + H2O = protopanaxatriol + 2 D-glucose
show the reaction diagram
-
ginsenoside Rg1 + H2O = ginsenoside Rh1 + D-glucose
show the reaction diagram
-

Product in Enzyme-catalyzed Reactions (8 results)

EC NUMBER
REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
UDP-alpha-D-glucose + ginsenoside F1 = UDP + (20S)-ginsenoside Rg1
show the reaction diagram
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-

Inhibitor in Enzyme-catalyzed Reactions (3 results)

EC NUMBER
COMMENTARY
LITERATURE
ENZYME 3D STRUCTURE
noncompetitive inhibition
-
from Panax ginseng roots, Rg1 alleviates left ventricular hypertrophy induced by abdominal aorta coarctation, and the protection appears to be due, at least in part, to its inhibitory effects on calcineurin and MAP kinase signaling pathways, overview
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inhibit ubiquitin-activating enzyme, from Panax ginseng roots, a traditional herbal medicine or food, causes 89.2% inhibition at 0.05 mM
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Enzyme Kinetic Parameters

kcat Value (Turnover Number) (1 result)

EC NUMBER
TURNOVER NUMBER [1/S]
TURNOVER NUMBER MAXIMUM [1/S]
COMMENTARY
LITERATURE
5.75
-
recombinant enzyme, pH 6.5, 30°C

KM Value (2 results)

EC NUMBER
KM VALUE [MM]
KM VALUE MAXIMUM [MM]
COMMENTARY
LITERATURE

IC50 Value (2 results)

EC NUMBER
IC50 VALUE
IC50 VALUE MAXIMUM
COMMENTARY
LITERATURE
0.00785
-
pH 7.5, 37°C
0.0035
-
recombinant enzyme, pH 7.6, 37°C

References & Links

Links to other databases for ginsenoside Rg1

ChEBI
PubChem
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PubChem