Ligand dolichol

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Basic Ligand Information

Molecular Structure
Picture of dolichol (click for magnification)
Molecular Formula
BRENDA Name
InChIKey
C100H164O
dolichol
KEVPZUBEAUSPNJ-MUXRWCLXSA-N
Synonyms:
ditrans,polycis-dolichol, dolichyl


Show all pahtways known for Show all BRENDA pathways known for dolichol

Roles as Enzyme Ligand

In Vivo Substrate in Enzyme-catalyzed Reactions (7 results)

EC NUMBER
PROVEN IN VIVO REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
CTP + dolichol = CDP + dolichyl phosphate
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In Vivo Product in Enzyme-catalyzed Reactions (1 result)

EC NUMBER
PROVEN IN VIVO REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
dolichyl phosphooligosaccharide + [flagellum protein FlaB2]-L-asparagine101 = dolichol + flagellum protein FlaB2 with the oligosaccharide chain attached by N-beta-D-glycosyl linkage to a protein L-asparagine
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Substrate in Enzyme-catalyzed Reactions (11 results)

EC NUMBER
REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
dolichol + O2 = ?
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3-sn-phosphatidylcholine + dolichol = 1-acyl-sn-glycero-3-phosphocholine + acyldolichol
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ATP + dolichol = ADP + dolichyl phosphate
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Product in Enzyme-catalyzed Reactions (10 results)

EC NUMBER
REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
dolichyl phosphate + H2O = dolichol + phosphate
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Activator in Enzyme-catalyzed Reactions (3 results)

EC NUMBER
COMMENTARY
LITERATURE
ENZYME 3D STRUCTURE
stimulates enzyme in the presence of inhibitory concentrations of phosphatidylcholine
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at a relative concentration of 30 mol% the lipid stimulates the reaction rate by a factor of 2.7
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Inhibitor in Enzyme-catalyzed Reactions (3 results)

EC NUMBER
COMMENTARY
LITERATURE
ENZYME 3D STRUCTURE
0.1 mM, strong, competitive inhibition
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Enzyme Kinetic Parameters

KM Value (8 results)

EC NUMBER
KM VALUE [MM]
KM VALUE MAXIMUM [MM]
COMMENTARY
LITERATURE
0.3
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References & Links

Links to other databases for dolichol

ChEBI
PubChem
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PubChem