Ligand histone H3 N6,N6,N6-trimethyl-L-lysine27

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Basic Ligand Information

Molecular Structure
Picture of histone H3 N6,N6,N6-trimethyl-L-lysine27 (click for magnification)
Molecular Formula
BRENDA Name
InChIKey
C35H62N12O9R2
histone H3 N6,N6,N6-trimethyl-L-lysine27
Synonyms:
a [histone H3]-N6,N6,N6-trimethyl-L-lysine27, [histone H3]-N6,N6,N6-trimethyl-L-lysine27, [histone H3]-N6,N6,N6-trimethyl-L-lysine 27

Roles as Enzyme Ligand

In Vivo Substrate in Enzyme-catalyzed Reactions (2 results)

EC NUMBER
PROVEN IN VIVO REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
[histone H3]-N6,N6,N6-trimethyl-L-lysine 27 + 2-oxoglutarate + O2 = [histone H3]-N6,N6-dimethyl-L-lysine 27 + succinate + formaldehyde + CO2
show the reaction diagram
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histone H3 N6,N6,N6-trimethyl-L-lysine27 + 2-oxoglutarate + O2 = histone H3 N6,N6-dimethyl-L-lysine27 + succinate + formaldehyde + CO2
show the reaction diagram
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In Vivo Product in Enzyme-catalyzed Reactions (3 results)

EC NUMBER
PROVEN IN VIVO REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE

Substrate in Enzyme-catalyzed Reactions (4 results)

EC NUMBER
REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
histone H3 N6,N6,N6-trimethyl-L-lysine27 + 2-oxoglutarate + O2 = histone H3 N6,N6-dimethyl-L-lysine27 + succinate + formaldehyde + CO2
show the reaction diagram
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Product in Enzyme-catalyzed Reactions (3 results)

EC NUMBER
REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE

Activator in Enzyme-catalyzed Reactions (1 result)

EC NUMBER
COMMENTARY
LITERATURE
ENZYME 3D STRUCTURE
the basal enzyme activity is stimulated by [histone H3]-N6,N6,N6-trimethyl-L-lysine27
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Enzyme Kinetic Parameters

References & Links

Links to other databases for histone H3 N6,N6,N6-trimethyl-L-lysine27

ChEBI
PubChem
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