Ligand 1-methyl-L-tryptophan

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Basic Ligand Information

Molecular Structure
Picture of 1-methyl-L-tryptophan (click for magnification)
Molecular Formula
BRENDA Name
InChIKey
C12H14N2O2
1-methyl-L-tryptophan
ZADWXFSZEAPBJS-JTQLQIEISA-N
Synonyms:
1-L-methyltryptophan, 1-methyl-tryptophan, 1-Methyltryptophan, 1-methyl tryptophan

Roles as Enzyme Ligand

Substrate in Enzyme-catalyzed Reactions (6 results)

EC NUMBER
REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
1-methyl-L-tryptophan + O2 = ?
show the reaction diagram
-
dimethylallyl diphosphate + 1-methyl-L-tryptophan = diphosphate + 1-methyl-4-(3-methylbut-2-enyl)-L-tryptophan
show the reaction diagram
-
dimethylallyl diphosphate + 1-methyl-L-tryptophan = diphosphate + 1-methyl-7-(3-methylbut-2-enyl)-L-tryptophan
show the reaction diagram
-
dimethylallyl diphosphate + 1-methyl-L-tryptophan = diphosphate + 1-methyl-5-(3-methylbut-2-enyl)-L-tryptophan
show the reaction diagram
-

Inhibitor in Enzyme-catalyzed Reactions (19 results)

EC NUMBER
COMMENTARY
LITERATURE
ENZYME 3D STRUCTURE
product inhibition
-

3D Structure of Enzyme-Ligand-Complex (PDB) (1 result)

EC NUMBER
ENZYME 3D STRUCTURE

Enzyme Kinetic Parameters

kcat Value (Turnover Number) (4 results)

EC NUMBER
TURNOVER NUMBER [1/S]
TURNOVER NUMBER MAXIMUM [1/S]
COMMENTARY
LITERATURE
0.0255
-
pH 7.8, 30°C

KM Value (4 results)

EC NUMBER
KM VALUE [MM]
KM VALUE MAXIMUM [MM]
COMMENTARY
LITERATURE
1.43
-
pH 7.8, 30°C

Ki Value (17 results)

EC NUMBER
KI VALUE [MM]
KI VALUE MAXIMUM [MM]
COMMENTARY
LITERATURE
0.031
-
mixed inhibition

IC50 Value (1 result)

EC NUMBER
IC50 VALUE
IC50 VALUE MAXIMUM
COMMENTARY
LITERATURE
0.00175
-
at 25°C in 0.2 M sodium phosphate buffer, pH 7.0

References & Links

Links to other databases for 1-methyl-L-tryptophan

ChEBI
PubChem
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PubChem