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Ligand 3-[(Z)-2-isocyanoethenyl]-1H-indole
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Basic Ligand Information
Related pathways
MetaCyc
12-epi-fischerindole biosynthesis, 12-epi-hapalindole biosynthesis, hapalindole H biosynthesis
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open all tablesRoles as Enzyme Ligand
In Vivo Product in Enzyme-catalyzed Reactions (1 result)
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EC NUMBER 
PROVEN IN VIVO REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
(2S)-3-(1H-indol-3-yl)-2-isocyanopropanoate + 2-oxoglutarate + O2 = 3-[(Z)-2-isocyanoethenyl]-1H-indole + succinate + 2 CO2 + H2O
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Substrate in Enzyme-catalyzed Reactions (2 results)
EC NUMBER
REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
dimethylallyl diphosphate + cis-indole nitrile = 3-[(Z)-2-isocyanoethenyl]-2-(3-methylbut-2-en-1-yl)-1H-indole + 3-[(Z)-2-isocyanoethenyl]-3-(3-methylbut-2-en-1-yl)-3H-indole + diphosphate
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geranyl diphosphate + cis-indole nitrile = 2-[(2E)-3,7-dimethylocta-2,6-dien-1-yl]-3-[(Z)-2-isocyanoethenyl]-1H-indole + 3-[(2E)-3,7-dimethylocta-2,6-dien-1-yl]-3-[(Z)-2-isocyanoethenyl]-3H-indole + diphosphate
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Product in Enzyme-catalyzed Reactions (1 result)
EC NUMBER
REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
(2S)-3-(1H-indol-3-yl)-2-isocyanopropanoate + 2-oxoglutarate + O2 = 3-[(Z)-2-isocyanoethenyl]-1H-indole + succinate + 2 CO2 + H2O
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Enzyme Kinetic Parameters
References & Links
Literature References (2)
Links to other databases for 3-[(Z)-2-isocyanoethenyl]-1H-indole
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Release 2026.1 (March 2026)
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