Ligand 3-(methylthio)propanoate

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Basic Ligand Information

Molecular Structure
Picture of 3-(methylthio)propanoate (click for magnification)
Molecular Formula
BRENDA Name
InChIKey
C4H8O2S
3-(methylthio)propanoate
CAOMCZAIALVUPA-UHFFFAOYSA-N
Synonyms:
3-(methylsulfanyl)propanoate, 3-(methylthio)propionate, 3-methyl-thiopropionate, 3-methylthiopropionate, methyl-3-mercaptopropanoic acid, methyl-3-mercaptopropionate, methylmercaptopropionate

Roles as Enzyme Ligand

In Vivo Substrate in Enzyme-catalyzed Reactions (3 results)

EC NUMBER
PROVEN IN VIVO REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
methylmercaptopropionate + coenzyme M = methyl-CoM + mercaptopropionate
show the reaction diagram
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In Vivo Product in Enzyme-catalyzed Reactions (3 results)

EC NUMBER
PROVEN IN VIVO REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
L-2-hydroxy-4-methylthiobutanoic acid + O2 = 3-(methylthio)propanoate + HCO3-
show the reaction diagram
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1,2-dihydroxy-5-(methylthio)pent-1-en-3-one + O2 = 3-(methylthio)propanoate + formate + CO
show the reaction diagram
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1,2-dihydroxy-5-(methylthio)pent-1-en-3-one + O2 = 3-(methylthio)propanoate + formate + CO
show the reaction diagram
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-

Substrate in Enzyme-catalyzed Reactions (6 results)

EC NUMBER
REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
methylmercaptopropionate + coenzyme M = methyl-CoM + mercaptopropionate
show the reaction diagram
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methylmercaptopropionate + HS-CoB = ?
show the reaction diagram
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ATP + 3-methylthiopropionate + CoA = ADP + phosphate + 3-methylthiopropionyl-CoA
show the reaction diagram
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ATP + 3-methylthiopropionate + CoA = ADP + phosphate + 3-methylthiopropionyl-CoA
show the reaction diagram
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Product in Enzyme-catalyzed Reactions (7 results)

EC NUMBER
REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
L-2-hydroxy-4-methylthiobutanoic acid + O2 = 3-(methylthio)propanoate + HCO3-
show the reaction diagram
-
1,2-dihydroxy-5-(methylthio)pent-1-en-3-one + O2 = 3-(methylthio)propanoate + formate + CO
show the reaction diagram
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a [methyl-Co(III) methanol-specific corrinoid protein] + 3-mercaptopropanoic acid = methyl-3-mercaptopropanoic acid + a [Co(I) methanol-specific corrinoid protein]
show the reaction diagram
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[methyl-Co(III) trimethylamine-specific corrinoid protein] + 3-mercaptopropionate = methyl-3-mercaptopropionate + [Co(I) trimethylamine-specific corrinoid protein]
show the reaction diagram
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3-(S,S-dimethylsulfonio)propanoate + tetrahydrofolate = 3-(methylthio)propanoate + 5-methyltetrahydrofolate
show the reaction diagram
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Inhibitor in Enzyme-catalyzed Reactions (3 results)

EC NUMBER
COMMENTARY
LITERATURE
ENZYME 3D STRUCTURE

Enzyme Kinetic Parameters

kcat Value (Turnover Number) (3 results)

EC NUMBER
TURNOVER NUMBER [1/S]
TURNOVER NUMBER MAXIMUM [1/S]
COMMENTARY
LITERATURE

KM Value (4 results)

EC NUMBER
KM VALUE [MM]
KM VALUE MAXIMUM [MM]
COMMENTARY
LITERATURE
10
-
pH 7.0, 37°C

Ki Value (2 results)

EC NUMBER
KI VALUE [MM]
KI VALUE MAXIMUM [MM]
COMMENTARY
LITERATURE

References & Links

Links to other databases for 3-(methylthio)propanoate

ChEBI
PubChem
ChEBI
PubChem