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Characterization and purification of neutrophil ecto-phosphatidic acid phosphohydrolase
1997
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Calcium mobilization via sphingosine kinase in signalling by the FceRI antigen receptor
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Biochemical characterization of the reverse activity of rat brain ceramidase. A CoA-independent and fumonisin B1-insensitive ceramide synthase
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Characterization of the Drosophila sphingosine kinases and requirement for Sk2 in normal reproductive function
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Arabidopsis sphingosine kinase and the effects of phytosphingosine-1-phosphate on stomatal aperture
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2007
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Structural and mechanistic analyses of endo-glycoceramidase II, a membrane-associated family 5 glycosidase in the Apo and GM3 ganglioside-bound forms
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Cloning and characterization of rat sphingosine kinase 1 with an N-terminal extension
2007
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Characterization of the yeast DGK1-encoded CTP-dependent diacylglycerol kinase
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Purification and characterization of a second type of neutral ceramidase from rat brain: a second more hydrophobic form of rat brain ceramidase
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Ceramide synthase is essential for endonuclease-mediated death of renal tubular epithelial cells induced by hypoxia-reoxygenation
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LASS3 (longevity assurance homologue 3) is a mainly testis-specific (dihydro)ceramide synthase with relatively broad substrate specificity
2006
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Substrate specificity, kinetic properties and inhibition by fumonisin B1 of ceramide synthase isoforms from Arabidopsis
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Ceramide synthase 1 is regulated by proteasomal mediated turnover
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Ceramide synthases as potential targets for therapeutic intervention in human diseases
2014
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N-(4-Hydroxyphenyl)retinamide elevates ceramide in neuroblastoma cell lines by coordinate activation of serine palmitoyltransferase and ceramide synthase
2001
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Ceramide synthase mediates daunorubicin-induced apoptosis an alternative mechanism for generating death signals
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Ceramide synthases 2, 5, and 6 confer distinct roles in radiation-induced apoptosis in HeLa cells
2010
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Subcellular localization and membrane topology of serine palmitoyltransferase, 3-dehydrosphinganine reductase, and sphinganine N-acyltransferase in mouse liver
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J. Biol. Chem.
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Fumonisin B1 inhibits sphingosine (sphinganine) N-acyltransferase and de novo sphingolipid biosynthesis in cultured neurons in situ
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Characterization of ceramide synthase 2 tissue distribution, substrate specificity, and inhibition by sphingosine 1-phosphate
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Ceramide synthesis is modulated by the sphingosine analog FTY720 via a mixture of uncompetitive and noncompetitive inhibition in an Acyl-CoA chain length-dependent manner
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FTY720 inhibits ceramide synthases and up-regulates dihydrosphingosine 1-phosphate formation in human lung endothelial cells
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Regulation of very-long acyl chain ceramide synthesis by acyl-CoA-binding protein
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2005
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J. Lipid Res.
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Partial purification and characterization of sphingosine N-acyltransferase (ceramide synthase) from bovine liver mitochondrion-rich fraction
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Lipids
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A three-step assay for ceramide synthase activity using a fluorescent substrate and HPLC
2015
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Assaying ceramide synthase activity in vitro and in living cells using liquid chromatography-mass spectrometry
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Ceramide synthase 6 modulates TRAIL sensitivity and nuclear translocation of active caspase-3 in colon cancer cells
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Upstream of growth and differentiation factor 1 (uog1), a mammalian homolog of the yeast longevity assurance gene 1 (LAG1), regulates N-stearoyl-sphinganine (C18-(dihydro)ceramide) synthesis in a fumonisin B1-independent manner in mammalian cells
2002
Venkataraman, K.; Riebeling, C.; Bodennec, J.; Riezman, H.; Allegood, J.C.; Sullards, M.C.; Merrill, A.H.Jr.; Futerman, A.H.
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