Ligand purine

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Basic Ligand Information

Molecular Structure
Picture of purine (click for magnification)
Molecular Formula
BRENDA Name
InChIKey
C5H4N4
purine
GACDQMDRPRGCTN-KQYNXXCUSA-N
Synonyms:
a purine base


Show all pahtways known for Show all BRENDA pathways known for purine

Roles as Enzyme Ligand

In Vivo Substrate in Enzyme-catalyzed Reactions (6 results)

EC NUMBER
PROVEN IN VIVO REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
purine + H2O + O2 = ?
show the reaction diagram
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purine + O2 + H2O = ? + H2O2
show the reaction diagram
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In Vivo Product in Enzyme-catalyzed Reactions (4 results)

EC NUMBER
PROVEN IN VIVO REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
alkylated DNA + H2O = 7-methyladenine + 7-methylguanine + 3-methyladenine + 3-methylguanine + purine + 6-chloropurine + xanthine + DNA
show the reaction diagram
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N-ribosylpurine + H2O = purine + D-ribose
show the reaction diagram
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Substrate in Enzyme-catalyzed Reactions (14 results)

EC NUMBER
REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
purine + O2 + H2O = ? + H2O2
show the reaction diagram
-
thymidine + purine = thymine + 9-(2-deoxy-beta-D-ribofuranosyl)-purine
show the reaction diagram
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Product in Enzyme-catalyzed Reactions (12 results)

EC NUMBER
REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
purine riboside + H2O = purine + D-ribose
show the reaction diagram
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alkylated DNA + H2O = 7-methyladenine + 7-methylguanine + 3-methyladenine + 3-methylguanine + purine + 6-chloropurine + xanthine + DNA
show the reaction diagram
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purine riboside + H2O = purine + D-ribose
show the reaction diagram
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adenine + H2O = purine + NH3
show the reaction diagram
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Activator in Enzyme-catalyzed Reactions (1 result)

EC NUMBER
COMMENTARY
LITERATURE
ENZYME 3D STRUCTURE
increases enzyme production
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Inhibitor in Enzyme-catalyzed Reactions (5 results)

EC NUMBER
COMMENTARY
LITERATURE
ENZYME 3D STRUCTURE
some inhibition
-
competitive inhibition
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Enzyme Kinetic Parameters

kcat Value (Turnover Number) (1 result)

EC NUMBER
TURNOVER NUMBER [1/S]
TURNOVER NUMBER MAXIMUM [1/S]
COMMENTARY
LITERATURE
0.7
-
electron acceptor: oxygen

KM Value (3 results)

EC NUMBER
KM VALUE [MM]
KM VALUE MAXIMUM [MM]
COMMENTARY
LITERATURE
0.0182
-
cosubstrate: NAD+
0.208
-
pH 8.5, 43°C
0.22
-
-

Ki Value (1 result)

EC NUMBER
KI VALUE [MM]
KI VALUE MAXIMUM [MM]
COMMENTARY
LITERATURE
1.1
-
pH 7.5, 25°C

References & Links

Links to other databases for purine

ChEBI
PubChem
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PubChem