Ligand L-Vinylglycine

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Basic Ligand Information

Molecular Structure
Picture of L-Vinylglycine (click for magnification)
Molecular Formula
BRENDA Name
InChIKey
C4H7NO2
L-Vinylglycine
RQVLGLPAZTUBKX-UHFFFAOYSA-N
Synonyms:
2-Amino-3-butenoate, 2-amino-3-butenoic acid, DL-vinylglycine, Vinylglycine

Roles as Enzyme Ligand

In Vivo Substrate in Enzyme-catalyzed Reactions (1 result)

EC NUMBER
PROVEN IN VIVO REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
vinylglycine = alpha-ketobutyrate + ammonia
show the reaction diagram
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In Vivo Product in Enzyme-catalyzed Reactions (1 result)

EC NUMBER
PROVEN IN VIVO REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
(R,S)-S-adenosyl-L-methionine = vinylglycine + methylthioadenosine
show the reaction diagram
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Substrate in Enzyme-catalyzed Reactions (16 results)

EC NUMBER
REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
2-amino-3-butenoic acid = 2-oxobutyric acid + NH3
show the reaction diagram
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DL-vinylglycine = ?
show the reaction diagram
-
L-vinylglycine = ?
show the reaction diagram
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ATP + UDP-N-acetyl-alpha-D-muramoyl-L-alanyl-D-glutamate + L-vinylglycine = ADP + phosphate + UDP-N-acetyl-alpha-D-muramoyl-L-alanyl-L-vinylglycine
show the reaction diagram
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L-2-aminoadipate + vinylglycine + L-valine + ATP = L-delta-(aminoadipyl)-L-vinylglycinyl-D-valine + AMP + diphosphate
show the reaction diagram
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ATP + UDP-N-acetylmuramate + L-vinylglycine = ADP + phosphate + UDP-N-acetylmuramoyl-L-vinylglycine
show the reaction diagram
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Product in Enzyme-catalyzed Reactions (1 result)

EC NUMBER
REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
(R,S)-S-adenosyl-L-methionine = vinylglycine + methylthioadenosine
show the reaction diagram
-

Inhibitor in Enzyme-catalyzed Reactions (12 results)

EC NUMBER
COMMENTARY
LITERATURE
ENZYME 3D STRUCTURE
irreversible inactivation
-
22% inhibition at 10 mM
-
microspectrophotometric measurements
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3D Structure of Enzyme-Ligand-Complex (PDB) (1 result)

EC NUMBER
ENZYME 3D STRUCTURE

Enzyme Kinetic Parameters

kcat Value (Turnover Number) (10 results)

EC NUMBER
TURNOVER NUMBER [1/S]
TURNOVER NUMBER MAXIMUM [1/S]
COMMENTARY
LITERATURE
0.61
-
pH 8.0, 25°C
15.3
-
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KM Value (9 results)

EC NUMBER
KM VALUE [MM]
KM VALUE MAXIMUM [MM]
COMMENTARY
LITERATURE
2.7
-
pH 8.0. 25°C
5.18
-
-
0.44
-
-

References & Links

Links to other databases for L-Vinylglycine

ChEBI
PubChem
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PubChem