Ligand D-tagatose

Please wait a moment until all data is loaded. This message will disappear when all data is loaded.

Basic Ligand Information

Molecular Structure
Picture of D-tagatose (click for magnification)
Molecular Formula
BRENDA Name
InChIKey
C6H12O6
D-tagatose
LKDRXBCSQODPBY-OEXCPVAWSA-N
Synonyms:
tagatose
Pathway Source
Pathways

Roles as Enzyme Ligand

In Vivo Substrate in Enzyme-catalyzed Reactions (2 results)

EC NUMBER
LITERATURE
REACTION DIAGRAM
PROVEN IN VIVO REACTION
ENZYME 3D STRUCTURE
show the reaction diagram
ATP + D-tagatose = ADP + D-tagatose 6-phosphate
-
show the reaction diagram
D-tagatose = D-sorbose
-

In Vivo Product in Enzyme-catalyzed Reactions (6 results)

EC NUMBER
LITERATURE
REACTION DIAGRAM
PROVEN IN VIVO REACTION
ENZYME 3D STRUCTURE
-
show the reaction diagram
D-altritol + NAD+ = D-tagatose + NADH + H+
-
-
show the reaction diagram
D-galactose = D-tagatose
-
-
show the reaction diagram
D-talose = D-tagatose
-

Substrate in Enzyme-catalyzed Reactions (20 results)

EC NUMBER
LITERATURE
REACTION DIAGRAM
REACTION
ENZYME 3D STRUCTURE
show the reaction diagram
D-tagatose + NADH = D-galactitol + NAD+
-
show the reaction diagram
D-tagatose + NADPH = ?
-
show the reaction diagram
tagatose + NADPH = ? + NADP+
-
show the reaction diagram
D-tagatose + acceptor = ?
-
show the reaction diagram
UDP-alpha-D-glucose + D-tagatose = ?
-
show the reaction diagram
sucrose + D-tagatose = alpha-D-glucopyranosyl-(1,1)-beta-D-tagatopyranose
-
show the reaction diagram
D-tagatose + alpha-D-glucose-1-phosphate = alpha-D-glucopyranosyl-(1->2)-beta-D-tagatose + phosphate
-
show the reaction diagram
ATP + D-tagatose = ADP + D-tagatose 6-phosphate
-
show the reaction diagram
ATP + D-tagatose = ?
-
show the reaction diagram
ATP + D-tagatose = ?
-
show the reaction diagram
D-tagatose + maltotriose = maltosyl-tagatose
-
show the reaction diagram
D-tagatose = D-fructose
-
show the reaction diagram
D-tagatose = D-sorbose
-
show the reaction diagram
D-tagatose = D-sorbose
-
show the reaction diagram
D-tagatose = D-sorbose
-
show the reaction diagram
D-tagatose = D-talose
-
show the reaction diagram
D-tagatose = D-galactose
-
show the reaction diagram
D-tagatose = D-talose
-

Product in Enzyme-catalyzed Reactions (22 results)

EC NUMBER
LITERATURE
REACTION DIAGRAM
REACTION
ENZYME 3D STRUCTURE
-
show the reaction diagram
D-altritol + NAD+ = D-tagatose + NADH + H+
-
-
show the reaction diagram
D-talitol + NADH + H+ = D-tagatose + NAD+
-
-
show the reaction diagram
DL-glycerol 3-phosphate + L-glyceraldehyde = L-fructose + D-tagatose
-
-
show the reaction diagram
D-fructose = D-tagatose
-
-
show the reaction diagram
D-sorbose = D-tagatose
-
-
show the reaction diagram
D-sorbose = D-tagatose
-
-
show the reaction diagram
D-sorbose = D-tagatose
-
-
show the reaction diagram
D-galactose = D-tagatose
-
-
show the reaction diagram
D-talose = D-tagatose
-
-
show the reaction diagram
D-galactose = D-tagatose
-
show the reaction diagram
D-galactose = D-tagatose
-
-
show the reaction diagram
D-talose = D-tagatose
-
-
show the reaction diagram
D-talose = D-tagatose
-
-
show the reaction diagram
D-galactose = D-tagatose
-
-
show the reaction diagram
D-talose = D-tagatose
-

Inhibitor in Enzyme-catalyzed Reactions (2 results)

COMMENTARY
EC NUMBER
LITERATURE
ENZYME 3D STRUCTURE
ZINC03830878, weak inhibition
-

Enzyme Kinetic Parameters

kcat Value (Turnover Number) (19 results)

COMMENTARY
EC NUMBER
LITERATURE
TURNOVER NUMBER [1/S]
TURNOVER NUMBER MAXIMUM [1/S]
at pH 7.5 and 85°C
1.5
-
in McIlvaine buffer (pH 7.5), at 35°C
0.00545
-
pH 7.0, 55°C, recombinant enzyme
4.7
-
recombinant wild-type enzyme, pH 8.5, 35°C
48.31
-
recombinant mutant R118W, pH 8.5, 35°C
51.25
-
pH 8.0, 60°C
0.057
-
pH 8.0, 45°C, mutant enzyme I66F
64
-
pH 8.0, 45°C, wild-type enzyme
194
-
pH 8.0, 45°C, mutant enzyme I66Y
56
-
pH 8.0, 45°C, mutant enzyme I66W
11
-
pH 8.0, 45°C, mutant enzyme I66V
100
-
pH 8.0, 45°C, mutant enzyme I66L
50
-
pH 8.0, 45°C, mutant enzyme I66G
33
-
pH 8.0, 45°C, mutant enzyme I66C
44
-
pH 8.0, 45°C, mutant enzyme I66A
23
-
pH 8.0, 45°C, mutant enzyme A107P
136
-
pH 7.0, 37°C, whole cells
0.82
-
pH 7.0, 37°C, purified enzyme
0.06
-
in 50 mM glycine-NaOH buffer (pH 9.0), at 40°C
40.8
-

KM Value (26 results)

COMMENTARY
EC NUMBER
KM VALUE [MM]
KM VALUE MAXIMUM [MM]
LITERATURE
at 22°C, pH 7.5
0.8
-
25°C, pH 7
0.9
-
25°C, pH 7.5, MgATP2-: 4mM
0.9
-
at pH 7.5 and 85°C
53
-
in McIlvaine buffer (pH 7.5), at 35°C
2
37
pH 7.0, 55°C, recombinant enzyme
339
-
recombinant wild-type enzyme, pH 8.5, 35°C
137.9
-
recombinant mutant R118W, pH 8.5, 35°C
0.98
-
pH 8.0, 60°C
140
-
pH 7.5, 30°C
55
-
pH 8.0, 45°C, mutant enzyme A107P
429
-
pH 8.0, 45°C, mutant enzyme I66A
1640
-
pH 8.0, 45°C, mutant enzyme I66C
6
11
pH 8.0, 45°C, mutant enzyme I66F
694
-
pH 8.0, 45°C, mutant enzyme I66G
1369
-
pH 8.0, 45°C, mutant enzyme I66L
1408
-
pH 8.0, 45°C, mutant enzyme I66V
1146
-
pH 8.0, 45°C, mutant enzyme I66W
213
-
pH 8.0, 45°C, mutant enzyme I66Y
696
-
pH 8.0, 45°C, wild-type enzyme
91
-
pH 7.0, 37°C, whole cells
114
-
pH 7.0, 37°C, purified enzyme
11
-
in 50 mM glycine-NaOH buffer (pH 9.0), at 40°C
39.2
-

References & Links

Links to other databases for D-tagatose

ChEBI
PubChem
-
PubChem