Ligand 3-deazaadenosine

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Basic Ligand Information

Molecular Structure
Picture of 3-deazaadenosine (click for magnification)
Molecular Formula
BRENDA Name
InChIKey
C11H14N4O4
3-deazaadenosine
DBZQFUNLCALWDY-PNHWDRBUSA-N
Synonyms:
3'-deazaadenosine, 3-deaza-adenosine, deazaadenosine

Roles as Enzyme Ligand

Substrate in Enzyme-catalyzed Reactions (7 results)

EC NUMBER
REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE

Activator in Enzyme-catalyzed Reactions (2 results)

EC NUMBER
COMMENTARY
LITERATURE
ENZYME 3D STRUCTURE
about 10% increased activity at 0.1 mM
-

Inhibitor in Enzyme-catalyzed Reactions (14 results)

EC NUMBER
COMMENTARY
LITERATURE
ENZYME 3D STRUCTURE
about 5% inhibition at 0.1 mM
-

3D Structure of Enzyme-Ligand-Complex (PDB) (13 results)

Enzyme Kinetic Parameters

kcat Value (Turnover Number) (1 result)

EC NUMBER
TURNOVER NUMBER [1/S]
TURNOVER NUMBER MAXIMUM [1/S]
COMMENTARY
LITERATURE
0.009
-
at pH 7.0 and 35°C

KM Value (3 results)

EC NUMBER
KM VALUE [MM]
KM VALUE MAXIMUM [MM]
COMMENTARY
LITERATURE
0.0022
-
at pH 7.0 and 35°C

Ki Value (7 results)

EC NUMBER
KI VALUE [MM]
KI VALUE MAXIMUM [MM]
COMMENTARY
LITERATURE
0.9
-
pH 8.6
0.0002
-
pH 7.2, 35°C, His-tagged enzyme form

IC50 Value (1 result)

EC NUMBER
IC50 VALUE
IC50 VALUE MAXIMUM
COMMENTARY
LITERATURE
0.00552
-
at pH 8.0 and 37°C

References & Links

Links to other databases for 3-deazaadenosine

ChEBI
PubChem
-
PubChem