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Ligand N1-methylguanine in DNA

Basic Ligand Information

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Roles as Enzyme Ligand

Substrate in Enzyme-catalyzed Reactions (1 result)

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EC NUMBER

REACTION

REACTION DIAGRAM

LITERATURE

ENZYME 3D STRUCTURE

1.14.11.33

N1-methylguanine in DNA + 2-oxoglutarate + O2 = guanine in DNA + formaldehyde + succinate + CO2

740305

-

Enzyme Kinetic Parameters

References & Links

Literature References (1)

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BRENDA REFERENCE ID

PUBMED ID

TITLE

YEAR

AUTHORS

JOURNAL

VOLUME

PAGES

740305

26919079

Adaptive response enzyme AlkB preferentially repairs 1-methylguanine and 3-methylthymine adducts in double-stranded DNA

2016

Chen, F.; Tang, Q.; Bian, K.; Humulock, Z.; Yang, X.; Jost, M.; Drennan, C.; Essigmann, J.; Li, D.

Chem. Res. Toxicol.

29

687-693

Links to other databases for N1-methylguanine in DNA

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