Ligand N-methyl-L-phenylalanine
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Basic Ligand Information
Molecular Structure

C10H13NO2
N-methyl-L-phenylalanine
SCIFESDRCALIIM-VIFPVBQESA-N
N-methyl L-phenylalanine, N-methylphenylalanine
Roles as Enzyme Ligand
Substrate in Enzyme-catalyzed Reactions (3 results)
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N-methyl-L-phenylalanine + O2 + H2O = L-phenylalanine + formaldehyde + H2O2
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N-methyl L-phenylalanine + 2,6-dichlorophenolindophenol + H2O = L-phenylalanine + formaldehyde + reduced 2,6-dichlorophenolindophenol
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N-methyl-L-phenylalanine = trans-cinnamate + methylamine
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Product in Enzyme-catalyzed Reactions (2 results)
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phenylpyruvate + methylamine + NADPH = N-methylphenylalanine + NADP+ + H2O
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phenylpyruvate + methylamine + NADPH + H+ = N-methyl-L-phenylalanine + NADP+
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3D Structure of Enzyme-Ligand-Complex (PDB) (25 results)
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Enzyme Kinetic Parameters
kcat Value (Turnover Number) (1 result)
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KM Value (2 results)
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References & Links
Literature References (3)
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Specificity of rabbit kidney demethylase
1954
Moritani, M.; Tung, T.C.; Fujii, S.; Mito, H.; Izumiya, N.; Kenmochi, K.; Hirohata, R.
J. Biol. Chem.
209
485-492
N-methylglutamate dehydrogenase: kinetic studies on the solubilized enzyme
1972
Hersh, L.B.; Stark, M.J.; Worthen, S.; Fiero, M.K.
Arch. Biochem. Biophys.
150
219-226
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Mechanistic investigation of phenylalanine ammonia lyase by using N-methylated phenylalanines
2003
Viergutz, S.; Poppe, L.; Tomin, A.; Retey, J.
Helv. Chim. Acta
86
3601-3612
Links to other databases for N-methyl-L-phenylalanine