Ligand methyl-CoM

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Basic Ligand Information

Molecular Structure
Picture of methyl-CoM (click for magnification)
Molecular Formula
BRENDA Name
InChIKey
C3H8O3S2
methyl-CoM
FGMRHOCVEPGURB-UHFFFAOYSA-N
Synonyms:
(2-methylthio)ethanesulfonate, 2-(methylsulfanyl)ethane-1-sulfonate, 2-(methylthio)ethanesulfonate, 2-(methylthio)ethanesulfonate (methyl-CoM), 2-(methylthio)ethansulfonate, CH3-S-CoM, CH3-SCoM, methyl-coenzyme M, methyl coenzyme M, methylcoenzyme M


Show all pahtways known for Show all BRENDA pathways known for methyl-CoM

Roles as Enzyme Ligand

In Vivo Substrate in Enzyme-catalyzed Reactions (9 results)

EC NUMBER
PROVEN IN VIVO REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
5,6,7,8-tetrahydromethanopterin + methyl-coenzyme M = 5-methyl-5,6,7,8-tetrahydromethanopterin + coenzyme M + H+
show the reaction diagram
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In Vivo Product in Enzyme-catalyzed Reactions (15 results)

EC NUMBER
PROVEN IN VIVO REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
a [methyl-Co(III) methanol-specific corrinoid protein] + coenzyme M = methyl-CoM + a [Co(I) methanol-specific corrinoid protein]
show the reaction diagram
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Substrate in Enzyme-catalyzed Reactions (17 results)

EC NUMBER
REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
5,6,7,8-tetrahydromethanopterin + methyl-coenzyme M = 5-methyl-5,6,7,8-tetrahydromethanopterin + coenzyme M + H+
show the reaction diagram
-

Product in Enzyme-catalyzed Reactions (19 results)

EC NUMBER
REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
a [methyl-Co(III) methanol-specific corrinoid protein] + coenzyme M = methyl-CoM + a [Co(I) methanol-specific corrinoid protein]
show the reaction diagram
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CoM-S-S-CoB + methane = methyl-CoM + CoB
show the reaction diagram
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Enzyme Kinetic Parameters

KM Value (11 results)

EC NUMBER
KM VALUE [MM]
KM VALUE MAXIMUM [MM]
COMMENTARY
LITERATURE
3.7
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References & Links

Links to other databases for methyl-CoM

ChEBI
PubChem
ChEBI
PubChem